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4KKG
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BU of 4kkg by Molmil
Crystal structure of apo and AMP-bound JNK3
Descriptor: Mitogen-activated protein kinase 10
Authors:Han, B.G, Shim, M.B, Ahn, H.C.
Deposit date:2013-05-06
Release date:2014-05-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:crystal structure of apo and AMP-bound JNK3
To be Published
1XMV
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BU of 1xmv by Molmil
E. coli RecA in complex with MgADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RecA protein
Authors:Bell, C.E, Xing, X.
Deposit date:2004-10-04
Release date:2005-01-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of Escherichia coli RecA in Complex with MgADP and MnAMP-PNP(,).
Biochemistry, 43, 2004
2WZX
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BU of 2wzx by Molmil
AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA)IN COMPLEX WITH compound M-02
Descriptor: (3R)-1-[(4S)-azepan-4-ylcarbamoyl]-3-(sulfoamino)-L-proline, BETA-LACTAMASE, CHLORIDE ION
Authors:Fitzgerald, P.M.D, Sharma, N, Lu, J.
Deposit date:2009-12-03
Release date:2010-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Side Chain Sar of Bicyclic Beta-Lactamase Inhibitors (Blis). 1. Discovery of a Class C Bli for Combination with Imipinem.
Bioorg.Med.Chem.Lett., 20, 2010
5E7J
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BU of 5e7j by Molmil
Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 bound to AMP
Descriptor: ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DDX3X
Authors:Floor, S.N, Condon, K.J, Doudna, J.A.
Deposit date:2015-10-12
Release date:2015-12-02
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3.
J.Biol.Chem., 291, 2016
2VFL
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BU of 2vfl by Molmil
AKAP18 delta central domain - CMP
Descriptor: AKAP18 DELTA, CYTIDINE-5'-MONOPHOSPHATE
Authors:Gold, M.G, Smith, F.D, Scott, J.D, Barford, D.
Deposit date:2007-11-05
Release date:2008-05-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Akap18 Contains a Phosphoesterase Domain that Binds AMP
J.Mol.Biol., 375, 2008
2WZZ
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BU of 2wzz by Molmil
AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA)IN COMPLEX WITH compound M-03
Descriptor: (3R)-1-[(4R)-AZEPAN-4-YLCARBAMOYL]-3-(SULFOAMINO)-L-PROLINE, BETA-LACTAMASE, CHLORIDE ION
Authors:Fitzgerald, P.M.D, Sharma, N, Lu, J.
Deposit date:2009-12-03
Release date:2010-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Side Chain Sar of Bicyclic Beta-Lactamase Inhibitors (Blis). 1. Discovery of a Class C Bli for Combination with Imipinem.
Bioorg.Med.Chem.Lett., 20, 2010
4NO5
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BU of 4no5 by Molmil
Crystal structure of non-phosphorylated form of AMPD2 phosphopeptide bound to HLA-A2
Descriptor: 1,2-ETHANEDIOL, AMP deaminase 2, Beta-2-microglobulin, ...
Authors:Mohammed, F, Stones, D.H, Willcox, B.E.
Deposit date:2013-11-19
Release date:2014-12-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
2GSU
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BU of 2gsu by Molmil
Structure of Xac Nucleotide Pyrophosphatase/Phosphodiesterase in Complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, ZINC ION, phosphodiesterase-nucleotide pyrophosphatase
Authors:Zalatan, J.G, Fenn, T.D, Brunger, A.T, Herschlag, D.
Deposit date:2006-04-26
Release date:2006-08-01
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional comparisons of nucleotide pyrophosphatase/phosphodiesterase and alkaline phosphatase: implications for mechanism and evolution
Biochemistry, 45, 2006
7MWY
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BU of 7mwy by Molmil
Structure of the drosophila STING cyclic dinucleotide binding domain
Descriptor: STING
Authors:Slavik, K.M, Ragucci, A.E, Kranzusch, P.J.
Deposit date:2021-05-17
Release date:2021-07-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
8I3I
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BU of 8i3i by Molmil
Acyl-ACP synthetase structure bound to AMP-PNP in the presence of MgCl2
Descriptor: Acyl-acyl carrier protein synthetase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y.
Deposit date:2023-01-17
Release date:2024-01-24
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Acyl-ACP synthetase structure bound to AMP-PNP in the presence of MgCl2
To Be Published
7AHD
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BU of 7ahd by Molmil
OpuA (E190Q) occluded
Descriptor: ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHC
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BU of 7ahc by Molmil
OpuA apo inward-facing
Descriptor: ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component
Authors:Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
Deposit date:2020-09-24
Release date:2020-11-25
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7OML
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BU of 7oml by Molmil
Bacillus subtilis phosphoglucomutase GlmM (metal bound)
Descriptor: MAGNESIUM ION, Phosphoglucosamine mutase
Authors:Pathania, M, Grundling, A.G, Freemont, P.
Deposit date:2021-05-24
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM.
J.Biol.Chem., 297, 2021
7OJR
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BU of 7ojr by Molmil
Bacillus subtilis phosphoglucomutase GlmM (phosphate bound)
Descriptor: PHOSPHATE ION, Phosphoglucosamine mutase
Authors:Pathania, M, Grundling, A.G, Freemont, P.
Deposit date:2021-05-17
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM.
J.Biol.Chem., 297, 2021
2CGH
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BU of 2cgh by Molmil
crystal structure of biotin ligase from Mycobacterium tuberculosis
Descriptor: BIOTIN LIGASE
Authors:Ma, Q, Wilmanns, M.
Deposit date:2006-03-06
Release date:2007-05-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Active Site Conformational Changes Upon Reaction Intermediate Biotinyl-5'-AMP Binding in Biotin Protein Ligase from Mycobacterium Tuberculosis.
Protein Sci., 23, 2014
3NGN
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BU of 3ngn by Molmil
Crystal structure of the human CNOT6L nuclease domain in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, CCR4-NOT transcription complex subunit 6-like
Authors:Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z.
Deposit date:2010-06-12
Release date:2010-07-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J., 2010
6XB3
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BU of 6xb3 by Molmil
Structure of AcNPV poxin in post-reactive state with Gp[2'-5']Ap[3']
Descriptor: 2',5'-GpAp, Poxin
Authors:Eaglesham, J.B, McCarty, K.L, Kranzusch, P.J.
Deposit date:2020-06-05
Release date:2020-11-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict.
Elife, 9, 2020
4DH1
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BU of 4dh1 by Molmil
Low temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with low Mg2+, ATP and IP20
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Kovalevsky, A.Y, Langan, P.
Deposit date:2012-01-27
Release date:2012-06-27
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity.
Acta Crystallogr.,Sect.D, 68, 2012
3UK2
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BU of 3uk2 by Molmil
The structure of Pantothenate synthetase from Burkholderia thailandensis
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-11-08
Release date:2011-11-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
5FCB
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BU of 5fcb by Molmil
Murine SMPDL3A in complex with AMP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, Acid sphingomyelinase-like phosphodiesterase 3a, ...
Authors:Gorelik, A, Illes, K, Superti-Furga, G, Nagar, B.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A.
J.Biol.Chem., 291, 2016
3TW2
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BU of 3tw2 by Molmil
High resolution structure of human histidine triad nucleotide-binding protein 1 (hHINT1)/AMP complex in a monoclinic space group
Descriptor: ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1
Authors:Dolot, R.M, Wlodarczyk, A, Ozga, M, Krakowiak, A, Nawrot, B.
Deposit date:2011-09-21
Release date:2011-11-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:A new crystal form of human histidine triad nucleotide-binding protein 1 (hHINT1) in complex with adenosine 5'-monophosphate at 1.38 A resolution.
Acta Crystallogr.,Sect.F, 68, 2012
2QUR
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BU of 2qur by Molmil
Crystal Structure of F327A/K285P Mutant of cAMP-dependent Protein Kinase
Descriptor: 20-mer fragment from cAMP-dependent protein kinase inhibitor alpha, ADENOSINE-5'-DIPHOSPHATE, cAMP-dependent protein kinase, ...
Authors:Taylor, S.S, Yang, J, Wu, J.
Deposit date:2007-08-06
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Contribution of non-catalytic core residues to activity and regulation in protein kinase A.
J.Biol.Chem., 284, 2009
3SGI
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BU of 3sgi by Molmil
Crystal structure of DNA ligase A BRCT domain deleted mutant of Mycobacterium tuberculosis
Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase
Authors:Kukshal, V, Ravishankar, R.
Deposit date:2011-06-15
Release date:2012-06-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal Structure of Domain deleted mutant of Mycobacterium tuberculosis NAD+ dependent DNA ligase capture the AMP cofactor in a new state
To be Published
4LOH
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BU of 4loh by Molmil
Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(3',5')p]
Descriptor: Stimulator of interferon genes protein, cGAMP
Authors:Gao, P, Patel, D.J.
Deposit date:2013-07-12
Release date:2013-08-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA.
Cell(Cambridge,Mass.), 154, 2013
4LOJ
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BU of 4loj by Molmil
Crystal structure of mSting in complex with c[G(2',5')pA(3',5')p]
Descriptor: Stimulator of interferon genes protein, cGAMP
Authors:Gao, P, Patel, D.J.
Deposit date:2013-07-12
Release date:2013-08-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA.
Cell(Cambridge,Mass.), 154, 2013

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