3HDY
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![BU of 3hdy by Molmil](/molmil-images/mine/3hdy) | Crystal Structure of UDP-galactopyranose mutase (reduced form) in complex with substrate | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, GALACTOSE-URIDINE-5'-DIPHOSPHATE, ... | Authors: | Partha, S.K, van Straaten, K.E, Sanders, D.A.R. | Deposit date: | 2009-05-07 | Release date: | 2009-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of substrate binding to UDP-galactopyranose mutase: crystal structures in the reduced and oxidized state complexed with UDP-galactopyranose and UDP. J.Mol.Biol., 394, 2009
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8OTF
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2ZDV
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![BU of 2zdv by Molmil](/molmil-images/mine/2zdv) | Exploring Thrombin S1 pocket | Descriptor: | D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide, Hirudin variant-1, PHOSPHATE ION, ... | Authors: | Baum, B, Heine, A, Klebe, G. | Deposit date: | 2007-11-29 | Release date: | 2008-10-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Exploring Thrombin S1 pocket To be Published
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7PKY
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![BU of 7pky by Molmil](/molmil-images/mine/7pky) | Half-vault structure | Descriptor: | Major vault protein | Authors: | Guerra, P, Gonzalez-Alamos, M, Llauro, A, Casanas, A, Querol-Audi, J, de Pablo, P, Verdaguer, N. | Deposit date: | 2021-08-27 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Symmetry disruption commits vault particles to disassembly. Sci Adv, 8, 2022
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7RU7
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![BU of 7ru7 by Molmil](/molmil-images/mine/7ru7) | Crystal structure of BtrK, a decarboxylase involved in butirosin biosynthesis | Descriptor: | DI(HYDROXYETHYL)ETHER, L-glutamyl-[BtrI acyl-carrier protein] decarboxylase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Arenas, L.A.R, Paiva, F.C.R, Huang, F, Leadlay, P, Dias, M.V.B. | Deposit date: | 2021-08-16 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of BtrK, a decarboxylase involved in the (S)-4-amino-2-hydroxybutyrate (AHBA) formation during butirosin biosynthesis J.Mol.Struct., 1267, 2022
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7DVD
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![BU of 7dvd by Molmil](/molmil-images/mine/7dvd) | The crystal structure of p53 DNA binding domain and PUMA complex | Descriptor: | Bcl-2-binding component 3, isoforms 1/2, Cellular tumor antigen p53, ... | Authors: | Han, C.W, Lee, H.N, Jeong, M.S, Jang, S.B. | Deposit date: | 2021-01-13 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structural basis of the p53 DNA binding domain and PUMA complex. Biochem.Biophys.Res.Commun., 548, 2021
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8OTG
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![BU of 8otg by Molmil](/molmil-images/mine/8otg) | |
8OTH
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![BU of 8oth by Molmil](/molmil-images/mine/8oth) | |
7Q2X
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![BU of 7q2x by Molmil](/molmil-images/mine/7q2x) | Cryo-EM structure of clamped S.cerevisiae condensin-DNA complex (Form I) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Condensin complex subunit 1, ... | Authors: | Lee, B.-G, Rhodes, J, Lowe, J. | Deposit date: | 2021-10-26 | Release date: | 2022-03-23 | Last modified: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Clamping of DNA shuts the condensin neck gate. Proc.Natl.Acad.Sci.USA, 119, 2022
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7PLM
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![BU of 7plm by Molmil](/molmil-images/mine/7plm) | CryoEM reconstruction of pyruvate ferredoxin oxidoreductase (PFOR) in anaerobic conditions | Descriptor: | CALCIUM ION, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | Authors: | Cherrier, M.V, Vernede, X, Fenel, D, Martin, L, Arragain, B, Neumann, E, Fontecilla Camps, J.C, Schoehn, G, Nicolet, Y. | Deposit date: | 2021-08-31 | Release date: | 2022-03-23 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Oxygen-Sensitive Metalloprotein Structure Determination by Cryo-Electron Microscopy. Biomolecules, 12, 2022
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7AEB
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![BU of 7aeb by Molmil](/molmil-images/mine/7aeb) | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the baseplate complex in extended state applied 6-fold symmetry. | Descriptor: | Baseplate_J domain-containing protein, LysM domain-containing protein, Phage tail protein, ... | Authors: | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | Deposit date: | 2020-09-17 | Release date: | 2022-02-16 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis. Nat Microbiol, 7, 2022
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2Z7K
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![BU of 2z7k by Molmil](/molmil-images/mine/2z7k) | tRNA-Guanine transglycosylase (TGT) in complex with 2-Amino-lin-Benzoguanine | Descriptor: | 2,6-diamino-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | Authors: | Ritschel, T, Heine, A, Klebe, G. | Deposit date: | 2007-08-24 | Release date: | 2008-08-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT Chembiochem, 10, 2009
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7Q2Y
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![BU of 7q2y by Molmil](/molmil-images/mine/7q2y) | Cryo-EM structure of clamped S.cerevisiae condensin-DNA complex (form II) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Condensin complex subunit 1, ... | Authors: | Lee, B.-G, Rhodes, J, Lowe, J. | Deposit date: | 2021-10-26 | Release date: | 2022-03-23 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Clamping of DNA shuts the condensin neck gate. Proc.Natl.Acad.Sci.USA, 119, 2022
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7K79
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![BU of 7k79 by Molmil](/molmil-images/mine/7k79) | CBF3 | Descriptor: | Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, Suppressor of kinetochore protein 1 | Authors: | Ruifang, G, Yawen, B. | Deposit date: | 2020-09-22 | Release date: | 2021-03-31 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation. Nat Commun, 12, 2021
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7AE0
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![BU of 7ae0 by Molmil](/molmil-images/mine/7ae0) | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the sheath-tube module in extended state. | Descriptor: | Phage tail protein, Putative phage tail sheath protein FI | Authors: | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | Deposit date: | 2020-09-17 | Release date: | 2022-02-16 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis. Nat Microbiol, 7, 2022
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5KIR
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![BU of 5kir by Molmil](/molmil-images/mine/5kir) | The Structure of Vioxx Bound to Human COX-2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, GLYCEROL, ... | Authors: | Orlando, B.J, Malkowski, M.G. | Deposit date: | 2016-06-16 | Release date: | 2016-09-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.697 Å) | Cite: | Crystal structure of rofecoxib bound to human cyclooxygenase-2. Acta Crystallogr.,Sect.F, 72, 2016
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3HHD
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![BU of 3hhd by Molmil](/molmil-images/mine/3hhd) | Structure of the Human Fatty Acid Synthase KS-MAT Didomain as a Framework for Inhibitor Design. | Descriptor: | CHLORIDE ION, Fatty acid synthase | Authors: | Pappenberger, G.M, Benz, J, Thoma, R, Rudolph, M.G. | Deposit date: | 2009-05-15 | Release date: | 2010-02-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure of the human fatty acid synthase KS-MAT didomain as a framework for inhibitor design. J.Mol.Biol., 397, 2010
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7Q06
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![BU of 7q06 by Molmil](/molmil-images/mine/7q06) | Crystal structure of TPADO in complex with 2-OH-TPA | Descriptor: | 2-Hydroxyterephthalic acid, FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Zahn, M, Kincannon, W.M, DuBois, J.L, McGeehan, J.E. | Deposit date: | 2021-10-14 | Release date: | 2022-03-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Biochemical and structural characterization of an aromatic ring-hydroxylating dioxygenase for terephthalic acid catabolism. Proc.Natl.Acad.Sci.USA, 119, 2022
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2MFH
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![BU of 2mfh by Molmil](/molmil-images/mine/2mfh) | Csr/Rsm protein-RNA recognition - A molecular affinity ruler: RsmZ(36-44)/RsmE(dimer) 2:1 complex | Descriptor: | Carbon storage regulator homolog, RsmZ(36-44) RNA | Authors: | Duss, O, Diarra Dit Konte, N, Michel, E, Schubert, M, Allain, F.H.-T. | Deposit date: | 2013-10-11 | Release date: | 2014-02-26 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Molecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognition. Nucleic Acids Res., 42, 2014
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7Q05
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![BU of 7q05 by Molmil](/molmil-images/mine/7q05) | Crystal structure of TPADO in complex with TPA | Descriptor: | FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, Lysozyme, ... | Authors: | Zahn, M, Kincannon, W.M, DuBois, J.L, McGeehan, J.E. | Deposit date: | 2021-10-14 | Release date: | 2022-03-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Biochemical and structural characterization of an aromatic ring-hydroxylating dioxygenase for terephthalic acid catabolism. Proc.Natl.Acad.Sci.USA, 119, 2022
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5KKN
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![BU of 5kkn by Molmil](/molmil-images/mine/5kkn) | Crystal structure of human ACC2 BC domain in complex with ND-646, the primary amide of ND-630 | Descriptor: | 2-[1-[(2~{R})-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-bis(oxidanylidene)thieno[2,3-d]pyrimidin-3-yl]-2-methyl-propanamide, Acetyl-CoA carboxylase 2 | Authors: | Wang, R, Paul, D, Tong, L. | Deposit date: | 2016-06-22 | Release date: | 2016-07-13 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Proc.Natl.Acad.Sci.USA, 113, 2016
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2Z9W
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![BU of 2z9w by Molmil](/molmil-images/mine/2z9w) | Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxal | Descriptor: | 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE, Aspartate aminotransferase, GLYCEROL, ... | Authors: | Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. | Deposit date: | 2007-09-26 | Release date: | 2007-11-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J.Biol.Chem., 283, 2008
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5KKC
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![BU of 5kkc by Molmil](/molmil-images/mine/5kkc) | l-lactate dehydrogenase from rabbit muscle with the inhibitor 6DHNAD | Descriptor: | L-lactate dehydrogenase A chain, SULFATE ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(5-aminocarbonyl-2~{H}-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | Authors: | Meneely, K.M, Moran, G.R, Lamb, A.L. | Deposit date: | 2016-06-21 | Release date: | 2016-11-02 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.859 Å) | Cite: | Ligand binding phenomena that pertain to the metabolic function of renalase. Arch.Biochem.Biophys., 612, 2016
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7PH1
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![BU of 7ph1 by Molmil](/molmil-images/mine/7ph1) | Trypsin in complex with BPTI mutant (2S)-2-amino-4-monofluorobutanoic acid | Descriptor: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | Authors: | Dimos, N, Leppkes, J, Koksch, B, Loll, B. | Deposit date: | 2021-08-16 | Release date: | 2022-03-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Water Network in the Binding Pocket of Fluorinated BPTI-Trypsin Complexes─Insights from Simulation and Experiment. J.Phys.Chem.B, 126, 2022
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8OT6
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![BU of 8ot6 by Molmil](/molmil-images/mine/8ot6) | |