1XKH
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![BU of 1xkh by Molmil](/molmil-images/mine/1xkh) | Pyoverdine outer membrane receptor FpvA from Pseudomonas aeruginosa PAO1 bound to pyoverdine | Descriptor: | (1S)-1-CARBOXY-5-[(3-CARBOXYPROPANOYL)AMINO]-8,9-DIHYDROXY-1,2,3,4-TETRAHYDROPYRIMIDO[1,2-A]QUINOLIN-11-IUM, Ferripyoverdine receptor, Pyoverdin C-E, ... | Authors: | Cobessi, D, Celia, H, Folschweiller, N, Schalk, I.J, Abdallah, M.A, Pattus, F. | Deposit date: | 2004-09-29 | Release date: | 2005-03-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | The Crystal Structure of the Pyoverdine Outer Membrane Receptor FpvA from Pseudomonas aeruginosa at 3.6A Resolution J.Mol.Biol., 347, 2005
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1XKI
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![BU of 1xki by Molmil](/molmil-images/mine/1xki) | Crystal structure of human tear lipocalin/von Ebners gland protein | Descriptor: | CHLORIDE ION, Von Ebner's gland protein, ZINC ION | Authors: | Breustedt, D.A, Korndoerfer, I.P, Redl, B, Skerra, A. | Deposit date: | 2004-09-29 | Release date: | 2004-10-19 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands J.Biol.Chem., 280, 2005
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1XKJ
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![BU of 1xkj by Molmil](/molmil-images/mine/1xkj) | BACTERIAL LUCIFERASE BETA2 HOMODIMER | Descriptor: | BETA2 LUCIFERASE | Authors: | Tanner, J.J, Krause, K.L. | Deposit date: | 1996-10-08 | Release date: | 1997-07-07 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of bacterial luciferase beta 2 homodimer: implications for flavin binding. Biochemistry, 36, 1997
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1XKK
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![BU of 1xkk by Molmil](/molmil-images/mine/1xkk) | EGFR kinase domain complexed with a quinazoline inhibitor- GW572016 | Descriptor: | Epidermal growth factor receptor, N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE, PHOSPHATE ION | Authors: | Wood, E.R, Truesdale, A.T, McDonald, O.B, Yuan, D, Hassell, A, Dickerson, S.H, Ellis, B, Pennisi, C, Horne, E, Lackey, K, Alligood, K.J, Rusnak, D.W, Gilmer, T.M, Shewchuk, L.M. | Deposit date: | 2004-09-29 | Release date: | 2004-12-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells. Cancer Res., 64, 2004
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1XKL
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![BU of 1xkl by Molmil](/molmil-images/mine/1xkl) | Crystal Structure of Salicylic Acid-binding Protein 2 (SABP2) from Nicotiana tabacum, NESG Target AR2241 | Descriptor: | 2-AMINO-4H-1,3-BENZOXATHIIN-4-OL, salicylic acid-binding protein 2 | Authors: | Forouhar, F, Chen, Y, Chiang, Y, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-09-29 | Release date: | 2004-11-30 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity Proc.Natl.Acad.Sci.USA, 102, 2005
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1XKM
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![BU of 1xkm by Molmil](/molmil-images/mine/1xkm) | NMR structure of antimicrobial peptide distinctin in water | Descriptor: | Distinctin chain A, Distinctin chain B | Authors: | Amodeo, P, Raimondo, D, Andreotti, G, Motta, A, Scaloni, A. | Deposit date: | 2004-09-29 | Release date: | 2005-04-05 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | A folding-dependent mechanism of antimicrobial peptide resistance to degradation unveiled by solution structure of distinctin. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1XKN
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![BU of 1xkn by Molmil](/molmil-images/mine/1xkn) | Crystal Structure of the Putative Peptidyl-arginine Deiminase from Chlorobium tepidum, NESG Target CtR21 | Descriptor: | CHLORIDE ION, SODIUM ION, putative peptidyl-arginine deiminase | Authors: | Forouhar, F, Befeler, A.R, Vorobiev, S.M, Hussain, M, Ciano, M, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-09-29 | Release date: | 2004-11-16 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of the Putative Peptidyl-arginine Deiminase from Chlorobium tepidum, NESG Target CtR21 To be Published
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1XKO
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![BU of 1xko by Molmil](/molmil-images/mine/1xko) | Structure of Thermotoga maritima CheX | Descriptor: | CHEMOTAXIS protein cheX | Authors: | Park, S.Y, Chao, X, Gonzalez-Bonet, G, Beel, B.D, Bilwes, A.M, Crane, B.R. | Deposit date: | 2004-09-29 | Release date: | 2004-12-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structure and Function of an Unusual Family of Protein Phosphatases; The Bacterial Chemotaxis Proteins CheC and CheX. Mol.Cell, 16, 2004
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1XKP
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![BU of 1xkp by Molmil](/molmil-images/mine/1xkp) | Crystal structure of the virulence factor YopN in complex with its heterodimeric chaperone SycN-YscB | Descriptor: | Chaperone protein sycN, Chaperone protein yscB, putative membrane-bound Yop targeting protein YopN | Authors: | Schubot, F.D, Jackson, M.W, Penrose, K.J, Cherry, S, Tropea, J.E, Plano, G.V, Waugh, D.S. | Deposit date: | 2004-09-29 | Release date: | 2005-03-22 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Three-dimensional structure of a macromolecular assembly that regulates type III secretion in Yersinia pestis. J.Mol.Biol., 346, 2005
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1XKQ
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![BU of 1xkq by Molmil](/molmil-images/mine/1xkq) | Crystal Structure of Short-Chain Dehydrogenase/Reductase of unknown Function from Caenorhabditis Elegans with Cofactor | Descriptor: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, short-chain reductase family member (5D234) | Authors: | Schormann, N, Zhou, J, Karpova, E, Zhang, Y, Symersky, J, Bunzel, B, Huang, W.-Y, Arabshahi, A, Qiu, S, Luan, C.-H, Gray, R, Carson, M, Tsao, J, Luo, M, Johnson, D, Lu, S, Lin, G, Luo, D, Cao, Z, Li, S, McKinstry, A, Shang, Q, Chen, Y.-J, Bray, T, Nagy, L, DeLucas, L, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-09-29 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Short-Chain Dehydrogenase/Reductase of unknown Function from Caenorhabditis Elegans with Cofactor To be Published
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1XKR
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![BU of 1xkr by Molmil](/molmil-images/mine/1xkr) | X-ray Structure of Thermotoga maritima CheC | Descriptor: | chemotaxis protein CheC | Authors: | Park, S.Y, Chao, X, Gonzalez-Bonet, G, Beel, B.D, Bilwes, A.M, Crane, B.R. | Deposit date: | 2004-09-29 | Release date: | 2004-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure and Function of an Unusual Family of Protein Phosphatases; The Bacterial Chemotaxis Proteins CheC and CheX Mol.Cell, 16, 2004
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1XKS
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![BU of 1xks by Molmil](/molmil-images/mine/1xks) | |
1XKT
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![BU of 1xkt by Molmil](/molmil-images/mine/1xkt) | Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain | Descriptor: | fatty acid synthase | Authors: | Chakravarty, B, Gu, Z, Chirala, S.S, Wakil, S.J, Quiocho, F.A. | Deposit date: | 2004-09-29 | Release date: | 2004-10-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain. Proc.Natl.Acad.Sci.Usa, 101, 2004
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1XKU
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![BU of 1xku by Molmil](/molmil-images/mine/1xku) | Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Decorin | Authors: | Scott, P.G, McEwan, P.A, Dodd, C.M, Bergmann, E.M, Bishop, P.N, Bella, J. | Deposit date: | 2004-09-29 | Release date: | 2004-11-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan Proc.Natl.Acad.Sci.Usa, 101, 2004
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1XKV
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![BU of 1xkv by Molmil](/molmil-images/mine/1xkv) | Crystal Structure Of ATP-Dependent Phosphoenolpyruvate Carboxykinase From Thermus thermophilus HB8 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent phosphoenolpyruvate carboxykinase, CALCIUM ION, ... | Authors: | Sugahara, M, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-09-29 | Release date: | 2005-10-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of ATP-dependent phosphoenolpyruvate carboxykinase from Thermus thermophilus HB8 showing the structural basis of induced fit and thermostability. Acta Crystallogr.,Sect.D, 61, 2005
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1XKW
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![BU of 1xkw by Molmil](/molmil-images/mine/1xkw) | Pyochelin outer membrane receptor FptA from Pseudomonas aeruginosa | Descriptor: | 1,2-ETHANEDIOL, Fe(III)-pyochelin receptor, LAURYL DIMETHYLAMINE-N-OXIDE, ... | Authors: | Cobessi, D, Celia, H, Pattus, F. | Deposit date: | 2004-09-30 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure at high resolution of ferric-pyochelin and its membrane receptor FptA from Pseudomonas aeruginosa J.Mol.Biol., 352, 2005
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1XKX
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![BU of 1xkx by Molmil](/molmil-images/mine/1xkx) | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. | Descriptor: | 2-(BETA-D-GLUCOPYRANOSYL)-5-METHYL-1-BENZIMIDAZOLE, Glycogen phosphorylase, muscle form, ... | Authors: | Chrysina, E.D, Kosmopoulou, M.N, Tiraidis, C, Kardakaris, R, Bischler, N, Leonidas, D.D, Hadady, Z, Somsak, L, Docsa, T, Gergely, P, Oikonomakos, N.G. | Deposit date: | 2004-09-30 | Release date: | 2005-03-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site Protein Sci., 14, 2005
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1XKY
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![BU of 1xky by Molmil](/molmil-images/mine/1xky) | Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis at 1.94A Resolution. | Descriptor: | POTASSIUM ION, dihydrodipicolinate synthase | Authors: | Levdikov, V, Blagova, E, Fogg, M.J, Brannigan, J.A, Milioti, N, Wilkinson, A.J, Wilson, K.S. | Deposit date: | 2004-09-30 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution Proteins, 62, 2006
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1XKZ
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![BU of 1xkz by Molmil](/molmil-images/mine/1xkz) | Crystal structure of the acylated beta-lactam sensor domain of Blar1 from S. aureus | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACYLATED CEFTAZIDIME, Regulatory protein blaR1, ... | Authors: | Birck, C, Cha, J.Y, Cross, J, Schulze-Briese, C, Meroueh, S.O, Schlegel, H.B, Mobashery, S, Samama, J.-P. | Deposit date: | 2004-09-30 | Release date: | 2004-11-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | X-ray crystal structure of the acylated beta-lactam sensor domain of BlaR1 from Staphylococcus aureus and the mechanism of receptor activation for signal transduction J.Am.Chem.Soc., 126, 2004
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1XL0
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![BU of 1xl0 by Molmil](/molmil-images/mine/1xl0) | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. | Descriptor: | (1R)-1,5-anhydro-1-(5-methyl-1,3,4-oxadiazol-2-yl)-D-glucitol, Glycogen phosphorylase, muscle form, ... | Authors: | Chrysina, E.D, Kosmopoulou, M.N, Tiraidis, C, Kardakaris, R, Bischler, N, Leonidas, D.D, Hadady, Z, Somsak, L, Docsa, T, Gergely, P, Oikonomakos, N.G. | Deposit date: | 2004-09-30 | Release date: | 2005-03-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site Protein Sci., 14, 2005
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1XL1
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![BU of 1xl1 by Molmil](/molmil-images/mine/1xl1) | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. | Descriptor: | (1R)-1,5-anhydro-1-(5-methyl-1,3-benzothiazol-2-yl)-D-glucitol, Glycogen phosphorylase, muscle form, ... | Authors: | Chrysina, E.D, Kosmopoulou, M.N, Tiraidis, C, Kardakaris, R, Bischler, N, Leonidas, D.D, Hadady, Z, Somsak, L, Docsa, T, Gergely, P, Oikonomakos, N.G. | Deposit date: | 2004-09-30 | Release date: | 2005-03-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site Protein Sci., 14, 2005
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1XL2
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![BU of 1xl2 by Molmil](/molmil-images/mine/1xl2) | HIV-1 Protease in complex with pyrrolidinmethanamine | Descriptor: | CHLORIDE ION, GLYCEROL, N-BENZYL-2-(2,6-DIMETHYLPHENOXY)-N-[((3R,4S)-4-{[ISOBUTYL(PHENYLSULFONYL)AMINO]METHYL}PYRROLIDIN-3-YL)METHYL]ACETAMIDE, ... | Authors: | Boettcher, J, Specker, E, Heine, A, Klebe, G. | Deposit date: | 2004-09-30 | Release date: | 2005-06-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | An Old Target Revisited: Two New Privileged Skeletons and an Unexpected Binding Mode For HIV-Protease Inhibitors Angew.Chem.Int.Ed.Engl., 44, 2005
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1XL3
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![BU of 1xl3 by Molmil](/molmil-images/mine/1xl3) | Complex structure of Y.pestis virulence Factors YopN and TyeA | Descriptor: | Secretion control protein, protein type A | Authors: | Schubot, F.D, Jackson, M.W, Penrose, K.J, Cherry, S, Tropea, J.E, Plano, G.V, Waugh, D.S. | Deposit date: | 2004-09-30 | Release date: | 2005-03-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Three-dimensional structure of a macromolecular assembly that regulates type III secretion in Yersinia pestis. J.Mol.Biol., 346, 2005
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1XL4
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![BU of 1xl4 by Molmil](/molmil-images/mine/1xl4) | Intermediate gating structure 1 of the inwardly rectifying K+ channel KirBac3.1 | Descriptor: | Inward rectifier potassium channel, MAGNESIUM ION, POTASSIUM ION | Authors: | Gulbis, J.M, Kuo, A, Smith, B, Doyle, D.A, Edwards, A, Arrowsmith, C, Sundstrom, M. | Deposit date: | 2004-09-30 | Release date: | 2004-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Two intermediate gating state crystal structures of the KirBac3.1 K+ channel To be Published
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1XL5
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![BU of 1xl5 by Molmil](/molmil-images/mine/1xl5) | HIV-1 Protease in complex with amidhyroxysulfone | Descriptor: | CHLORIDE ION, N-{(1S)-1-(3-BROMOBENZYL)-4-[(4-BROMOPHENYL)SULFONYL]-6-METHYL-2-OXOHEPTYL}-2-(2,6-DIMETHYLPHENOXY)ACETAMIDE, PROTEASE RETROPEPSIN | Authors: | Boettcher, J, Specker, E, Heine, A, Klebe, G. | Deposit date: | 2004-09-30 | Release date: | 2005-06-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | An Old Target Revisited: Two New Privileged Skeletons and an Unexpected Binding Mode For HIV-Protease Inhibitors Angew.Chem.Int.Ed.Engl., 44, 2005
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