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3TUR
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BU of 3tur by Molmil
Crystal Structure of M. tuberculosis LD-transpeptidase type 2 complexed with a peptidoglycan fragment
Descriptor: 6-CARBOXYLYSINE, D-GLUTAMIC ACID, Di-mu-iodobis(ethylenediamine)diplatinum(II), ...
Authors:Bianchet, M.A, Erdemli, S.B, Gupta, R, Lamichhane, G, Amzel, L.M.
Deposit date:2011-09-17
Release date:2012-12-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2.
Structure, 20, 2012
7DQ8
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BU of 7dq8 by Molmil
Crystal structure of actinomycin D-echinomycin-d(ACGCGCT/AGCTCGT) complex
Descriptor: 2-CARBOXYQUINOXALINE, Actinomycin D, DNA (5'-D(P*AP*CP*GP*CP*GP*CP*T)-3'), ...
Authors:Satange, R.B, Hou, M.H.
Deposit date:2020-12-22
Release date:2021-12-29
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Synergistic binding of actinomycin D and echinomycin to DNA mismatch sites and their combined anti-tumour effects.
Nucleic Acids Res., 2023
7DQ0
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BU of 7dq0 by Molmil
Crystal structure of actinomycin D-echinomycin-d(ACGTGCT/AGCTCGT) complex
Descriptor: 2-CARBOXYQUINOXALINE, Actinomycin D, CHLORIDE ION, ...
Authors:Satange, R.B, Hou, M.H.
Deposit date:2020-12-22
Release date:2021-12-29
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synergistic binding of actinomycin D and echinomycin to DNA mismatch sites and their combined anti-tumour effects.
Nucleic Acids Res., 2023
2V57
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BU of 2v57 by Molmil
Crystal structure of the TetR-like transcriptional regulator LfrR from Mycobacterium smegmatis in complex with proflavine
Descriptor: ISOPROPYL ALCOHOL, PROFLAVIN, SULFATE ION, ...
Authors:Bellinzoni, M, Buroni, S, Riccardi, G, De Rossi, E, Alzari, P.M.
Deposit date:2008-10-02
Release date:2009-10-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Plasticity and Distinct Drug-Binding Modes of Lfrr, a Mycobacterial Efflux Pump Regulator.
J.Bacteriol., 191, 2009
4NNK
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BU of 4nnk by Molmil
Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide
Descriptor: 30S ribosomal protein S1
Authors:Yang, J, Liu, Y, Cai, Q, Lin, D.
Deposit date:2013-11-18
Release date:2014-12-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
4GSQ
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BU of 4gsq by Molmil
Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains
Descriptor: CALCIUM ION, GLYCEROL, Probable conserved lipoprotein LPPS
Authors:Kim, H.S, Kim, J, Im, H.N, Yoon, J.Y, An, D.R, Yoon, H.J, Kim, J.Y, Min, H.K, Kim, S.-J, Lee, J.Y, Han, B.W, Suh, S.W.
Deposit date:2012-08-28
Release date:2013-02-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains
Acta Crystallogr.,Sect.D, 69, 2013
3ZZM
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BU of 3zzm by Molmil
Crystal structure of Mycobacterium tuberculosis PurH with a novel bound nucleotide CFAIR, at 2.2 A resolution.
Descriptor: 5-(FORMYLAMINO)-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, GLYCEROL, ...
Authors:Le Nours, J, Bulloch, E.M.M, Zhang, Z, Greenwood, D.R, Middleditch, M.J, Dickson, J.M.J, Baker, E.N.
Deposit date:2011-09-02
Release date:2011-09-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium Tuberculosis Reveal a Novel Bound Nucleotide.
J.Biol.Chem., 286, 2011
4NNG
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BU of 4nng by Molmil
Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide
Descriptor: 30S ribosomal protein S1
Authors:Yang, J, Liu, Y, Cai, Q, Lin, D.
Deposit date:2013-11-18
Release date:2014-12-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
3TK1
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BU of 3tk1 by Molmil
Crystal structure of a MeaB and Rv1496 ortholog from Mycobacterium thermoresistible bound to GDP
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Membrane ATPase/protein kinase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-08-25
Release date:2011-10-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Mycobacterial MeaB and MMAA-like GTPases.
J.Struct.Funct.Genom., 16, 2015
3R9B
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BU of 3r9b by Molmil
Crystal structure of Mycobacterium smegmatis CYP164A2 in ligand free state
Descriptor: 1,2-ETHANEDIOL, CYTOCHROME P450 164A2, DODECANE, ...
Authors:Agnew, C.R.J, Warrilow, A.G.S, Kelly, S.L, Brady, R.L.
Deposit date:2011-03-25
Release date:2012-04-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:An enlarged, adaptable active site in CYP164 family P450 enzymes, the sole P450 in Mycobacterium leprae.
Antimicrob.Agents Chemother., 56, 2012
4AIV
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BU of 4aiv by Molmil
Crystal Structure of putative NADH-dependent nitrite reductase small subunit from Mycobacterium tuberculosis
Descriptor: GLYCEROL, PROBABLE NITRITE REDUCTASE [NAD(P)H] SMALL SUBUNIT NIRD
Authors:Izumi, A, Schnell, R, Schneider, G.
Deposit date:2012-02-15
Release date:2012-09-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Nird, the Small Subunit of the Nitrite Reductase Nirbd from Mycobacterium Tuberculosis, at 2.0 Angstrom Resolution
Proteins, 80, 2012
3U1P
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BU of 3u1p by Molmil
Crystal Structure of M. tuberculosis LD-transpeptidase type 2 with Modified Catalytic Cysteine (C354)
Descriptor: DI(HYDROXYETHYL)ETHER, Mycobacteria Tuberculosis LD-transpeptidase type 2
Authors:Erdemli, S, Bianchet, M.A, Gupta, R, Lamichhane, G, Amzel, L.M.
Deposit date:2011-09-30
Release date:2012-12-05
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2.
Structure, 20, 2012
3GO3
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BU of 3go3 by Molmil
Interactions of an echinomycin-DNA complex with manganese(II) ions
Descriptor: 2-CARBOXYQUINOXALINE, 5'-D(*AP*CP*GP*TP*AP*CP*GP*T)-3', DI(HYDROXYETHYL)ETHER, ...
Authors:Pfoh, R, Cuesta-Seijo, J.A, Sheldrick, G.M.
Deposit date:2009-03-18
Release date:2009-03-31
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Interaction of an Echinomycin-DNA Complex with Manganese Ion
Acta Crystallogr.,Sect.F, 65, 2009
2VJW
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BU of 2vjw by Molmil
crystal structure of the second GAF domain of DevS from Mycobacterium smegmatis
Descriptor: GAF FAMILY PROTEIN
Authors:Kang, B.S, Cho, H.Y, Cho, H.J.
Deposit date:2007-12-14
Release date:2008-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:O2- and No-Sensing Mechanism Through the Devsr Two- Component System in Mycobacterium Smegmatis.
J.Bacteriol., 190, 2008
3QI6
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BU of 3qi6 by Molmil
Crystal Structure of Cystathionine gamma-synthase MetB (Cgs) from Mycobacterium ulcerans Agy99
Descriptor: 1,2-ETHANEDIOL, Cystathionine gamma-synthase MetB (Cgs), GLYCEROL, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-01-26
Release date:2011-03-02
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure of the cystathionine [gamma]-synthase MetB from Mycobacterium ulcerans
Acta Crystallogr.,Sect.F, 67, 2011
2VZZ
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BU of 2vzz by Molmil
Crystal structure of Rv0802c from Mycobacterium tuberculosis in Complex with Succinyl-CoA
Descriptor: RV0802C, SUCCINYL-COENZYME A
Authors:Vetting, M.W, Errey, J.C, Blanchard, J.S.
Deposit date:2008-08-07
Release date:2009-04-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rv0802C from Mycobacterium Tuberculosis: The First Structure of a Succinyltransferase with the Gnat Fold.
Acta Crystallogr.,Sect.F, 64, 2008
3R9C
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BU of 3r9c by Molmil
Crystal structure of Mycobacterium smegmatis CYP164A2 with Econazole bound
Descriptor: 1,2-ETHANEDIOL, 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, Cytochrome P450 164A2, ...
Authors:Agnew, C.R.J, Kelly, S.L, Brady, R.L.
Deposit date:2011-03-25
Release date:2012-03-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:An enlarged, adaptable active site in CYP164 family P450 enzymes, the sole P450 in Mycobacterium leprae.
Antimicrob.Agents Chemother., 56, 2012
4M35
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BU of 4m35 by Molmil
Crystal structure of gated-pore mutant H126/141D of second DNA-Binding protein under starvation from Mycobacterium smegmatis
Descriptor: CHLORIDE ION, FE (II) ION, MAGNESIUM ION, ...
Authors:Williams, S.M, Chandran, A.V, Vijayabaskar, M.S, Roy, S, Balaram, H, Vishveshwara, S, Vijayan, M, Chatterji, D.
Deposit date:2013-08-06
Release date:2014-03-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A histidine aspartate ionic lock gates the iron passage in miniferritins from Mycobacterium smegmatis
J.Biol.Chem., 289, 2014
2Z9I
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BU of 2z9i by Molmil
Crystal structure of RV0983 from Mycobacterium tuberculosis- Proteolytically active form
Descriptor: GATV, PROBABLE SERINE PROTEASE PEPD, SVEQV
Authors:Palaninathan, S.K, Mohamedmohaideen, N.N, Sacchettini, J.C.
Deposit date:2007-09-20
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of the virulence-associated high-temperature requirement A of Mycobacterium tuberculosis
Biochemistry, 47, 2008
4AVA
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BU of 4ava by Molmil
Crystal structure of protein lysine acetyltransferase Rv0998 from Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ...
Authors:Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
Deposit date:2012-05-24
Release date:2012-07-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
3T5C
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BU of 3t5c by Molmil
Crystal structure of N-terminal domain of FACL13 from Mycobacterium tuberculosis in different space group C2
Descriptor: PROBABLE CHAIN-FATTY-ACID-CoA LIGASE FADD13
Authors:Goyal, A, Sankaranarayanan, R.
Deposit date:2011-07-27
Release date:2012-01-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Molecular basis of the functional divergence of fatty acyl-AMP ligase biosynthetic enzymes of Mycobacterium tuberculosis.
J.Mol.Biol., 416, 2012
4P0M
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BU of 4p0m by Molmil
Crystal structure of an evolved putative penicillin-binding protein homolog, Rv2911, from Mycobacterium tuberculosis
Descriptor: D-alanyl-D-alanine carboxypeptidase
Authors:Krieger, I, Yu, M, Bursey, E, Hung, L.-W, Terwilliger, T.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2014-02-21
Release date:2014-03-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Subfamily-Specific Adaptations in the Structures of Two Penicillin-Binding Proteins from Mycobacterium tuberculosis.
Plos One, 9, 2014
4LS9
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BU of 4ls9 by Molmil
Structure of mycobacterial nrnA homolog reveals multifunctional nuclease activities
Descriptor: DHH family protein, GLYCEROL, MANGANESE (II) ION
Authors:Kumar, D, Srivastav, R, Grover, A, Manjasetty, B.A, Sharma, R, Taneja, B.
Deposit date:2013-07-22
Release date:2014-07-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Unique subunit packing in mycobacterial nanoRNase leads to alternate substrate recognitions in DHH phosphodiesterases
Nucleic Acids Res., 42, 2014
3S0Q
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BU of 3s0q by Molmil
Peptidase module of the peptidoglycan hydrolase RipA (Rv1477) from Mycobacterium tuberculosis, catalytic site mutant (Cys383Ala) at 1.45 resolution
Descriptor: INVASION PROTEIN
Authors:Both, D, Schnell, R, Schneider, G.
Deposit date:2011-05-13
Release date:2011-08-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Peptidoglycan Remodeling in Mycobacterium tuberculosis: Comparison of Structures and Catalytic Activities of RipA and RipB.
J.Mol.Biol., 413, 2011
7CAD
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BU of 7cad by Molmil
Mycobacterium smegmatis SugABC complex
Descriptor: ABC sugar transporter, permease component, ABC transporter, ...
Authors:Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z.
Deposit date:2020-06-08
Release date:2020-12-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020

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