PDB: 593 件ウェブページステータス検索Chemie searchBIRD

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5U06	Grb7-SH2 with bicyclic peptide inhibitor containing a pY mimetic 分子名称: Growth factor receptor-bound protein 7, POTASSIUM ION, bicyclic peptide inhibitor: LYS-PHE-GLU-GLY-CMF-ASP-ASN-GLU-CST 著者 Watson, G.M, Wilce, J.A. 登録日 2016-11-22 公開日 2017-11-15 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery, Development, and Cellular Delivery of Potent and Selective Bicyclic Peptide Inhibitors of Grb7 Cancer Target. J. Med. Chem., 60, 2017
5TQS	Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the receptor tyrosine kinase ErbB2 分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, Receptor protein-tyrosine kinase 著者 Wuttke, D.S, McKercher, M.A. 登録日 2016-10-24 公開日 2017-04-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.876 Å) 主引用文献 Multimodal Recognition of Diverse Peptides by the C-Terminal SH2 Domain of Phospholipase C-gamma 1 Protein. Biochemistry, 56, 2017
2CI8	sh2 domain of human nck1 adaptor protein - uncomplexed 分子名称: CYTOPLASMIC PROTEIN NCK1, PENTAETHYLENE GLYCOL, SULFATE ION 著者 Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W. 登録日 2006-03-17 公開日 2006-04-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains. J.Biol.Chem., 281, 2006
2CIA	human nck2 sh2-domain in complex with a decaphosphopeptide from translocated intimin receptor (tir) of epec 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CYTOPLASMIC PROTEIN NCK2, ISOPROPYL ALCOHOL, ... 著者 Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W. 登録日 2006-03-17 公開日 2006-04-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains. J.Biol.Chem., 281, 2006
2CR4	Solution structure of the SH2 domain of human SH3BP2 protein 分子名称: SH3 domain-binding protein 2 著者 Hatta, R, Tomizawa, T, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-20 公開日 2005-11-20 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH2 domain of human SH3BP2 protein To be Published
2AOA	Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain 分子名称: 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Growth factor receptor-bound protein 2 著者 Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. 登録日 2005-08-12 公開日 2005-10-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005
2DX0	Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2 分子名称: Phospholipase C, gamma 2, SULFATE ION 著者 Handa, N, Takagi, T, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-08-22 公開日 2007-09-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2 To be Published
2DM0	Solution structure of the SH2 domain of human Tyrosine-protein kinase TXK 分子名称: Tyrosine-protein kinase TXK 著者 Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-20 公開日 2006-10-20 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH2 domain of human Tyrosine-protein kinase TXK To be Published
2DLZ	Solution structure of the SH2 domain of human protein vav-2 分子名称: Protein vav-2 著者 Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-20 公開日 2007-04-03 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH2 domain of human protein vav-2 To be Published
2CS0	Solution structure of the SH2 domain of human HSH2D protein 分子名称: Hematopoietic SH2 domain containing 著者 Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-20 公開日 2005-11-20 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH2 domain of human HSH2D protein To be published
2CRH	Solution structure of the SH2 domain of human proto-oncogene protein VAV1 分子名称: Vav proto-oncogene 著者 Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-20 公開日 2005-11-20 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH2 domain of human proto-oncogene protein VAV1 to be published
2AOB	Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain 分子名称: 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, Growth factor receptor-bound protein 2 著者 Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. 登録日 2005-08-12 公開日 2005-10-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005
2BBU	solution structure of mouse socs3 in complex with a phosphopeptide from the gp130 receptor 分子名称: GP130 PHOSPHOPEPTIDE, Suppressor of cytokine signaling 3 著者 Babon, J.J, Yao, S, Norton, R.S. 登録日 2005-10-17 公開日 2006-05-02 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability Mol.Cell, 22, 2006
2AUG	Crystal structure of the Grb14 SH2 domain 分子名称: Growth factor receptor-bound protein 14 著者 Depetris, R.S, Hu, J, Gimpelevich, I, Holt, L.J, Daly, R.J, Hubbard, S.R. 登録日 2005-08-27 公開日 2005-11-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for inhibition of the insulin receptor by the adaptor protein grb14. Mol.Cell, 20, 2005
2EKX	Solution structure of the human BMX SH2 domain 分子名称: Cytoplasmic tyrosine-protein kinase BMX 著者 Kasai, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-26 公開日 2007-10-02 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the human BMX SH2 domain To be Published
2CI9	Nck1 SH2-domain in complex with a dodecaphosphopeptide from EPEC protein Tir 分子名称: CYTOPLASMIC PROTEIN NCK1, TRANSLOCATED INTIMIN RECEPTOR 著者 Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W. 登録日 2006-03-17 公開日 2006-04-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains. J.Biol.Chem., 281, 2006
2EO3	Solution structure of the SH2 domain from human Crk-like protein 分子名称: Crk-like protein 著者 Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-28 公開日 2008-04-08 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH2 domain from human Crk-like protein To be Published
2DLY	Solution structure of the SH2 domain of murine Fyn-related kinase 分子名称: Fyn-related kinase 著者 Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-20 公開日 2006-10-20 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH2 domain of murine Fyn-related kinase To be Published
2DCR	Fully automated solution structure determination of the Fes SH2 domain 分子名称: Proto-oncogene tyrosine-protein kinase Fes/Fps 著者 Lopez-Mendez, B, Guntert, P. 登録日 2006-01-12 公開日 2006-10-17 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Automated protein structure determination from NMR spectra J.AM.CHEM.SOC., 128, 2006
2ECD	Solution structure of the human ABL2 SH2 domain 分子名称: Tyrosine-protein kinase ABL2 著者 Kasai, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-13 公開日 2008-02-19 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the human ABL2 SH2 domain To be Published
2EOB	Solution structure of the second SH2 domain from rat PLC gamma-2 分子名称: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 著者 Sano, R, Hayashi, F, Nagashima, T, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-29 公開日 2008-04-01 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the second SH2 domain from rat PLC gamma-2 To be Published
2EO6	Solution structure of the SH2 domain from mouse B-cell linker protein BLNK 分子名称: B-cell linker protein 著者 Sano, R, Hayashi, F, Kurosaki, C, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-29 公開日 2008-04-01 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH2 domain from mouse B-cell linker protein BLNK To be Published
2EYV	SH2 domain of CT10-Regulated Kinase 分子名称: v-crk sarcoma virus CT10 oncogene homolog isoform a 著者 Kobashigawa, Y, Tanaka, S, Inagaki, F. 登録日 2005-11-10 公開日 2006-11-10 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007
2ETZ	The NMR minimized average structure of the Itk SH2 domain bound to a phosphopeptide 分子名称: Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK 著者 Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H. 登録日 2005-10-27 公開日 2006-02-07 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide. J.Mol.Biol., 357, 2006
1MW4	Solution structure of the human Grb7-SH2 domain in complex with a 10 amino acid peptide pY1139 分子名称: Growth factor receptor-bound protein 7, Receptor protein-tyrosine kinase erbB-2 著者 Ivancic, M, Lyons, B.A. 登録日 2002-09-27 公開日 2003-09-09 最終更新日 2012-05-02 実験手法 SOLUTION NMR 主引用文献 Solution structure of the human Grb7-SH2 domain/erbB2 peptide complex and structural basis for Grb7 binding to ErbB2 J.BIOMOL.NMR, 27, 2003

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