5TQS

Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the receptor tyrosine kinase ErbB2

Summary for 5TQS

• Entry DOI: 10.2210/pdb5tqs/pdb
• Related: 5TQ1
• Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, Receptor protein-tyrosine kinase (3 entities in total)
• Functional Keywords: sh2, phospholipase, phosphopeptide, hydrolase
• Biological source: Bos taurus (Bovine); More
• Total number of polymer chains: 8
• Total formula weight: 53980.48

Authors

Wuttke, D.S.,McKercher, M.A. (deposition date: 2016-10-24, release date: 2017-04-19, Last modification date: 2023-11-15)

• Primary citation: McKercher, M.A.,Guan, X.,Tan, Z.,Wuttke, D.S.; Multimodal Recognition of Diverse Peptides by the C-Terminal SH2 Domain of Phospholipase C-gamma 1 Protein.; Biochemistry, 56:2225-2237, 2017; PubMed: 28376302; DOI: 10.1021/acs.biochem.7b00023

Experimental method

X-RAY DIFFRACTION (1.876 Å)