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5TQS

Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the receptor tyrosine kinase ErbB2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1polymer10111989.74UniProt (P08487)
Pfam (PF00017)
Bos taurus (Bovine)PLC-148,Phosphoinositide phospholipase C-gamma-1,Phospholipase C-II,PLC-II,Phospholipase C-gamma-1,PLC-gamma-1
2E, F, G, H
(E, F, H, G)
Receptor protein-tyrosine kinasepolymer111505.44UniProt (B4DTR1)
UniProt (by SIFTS) (P04626)
Homo sapiens
3I, J, K, L, M...
(A, B, C, D, E...)
waterwater18.0259Chemie (HOH)
Sequence modifications
A, B, C, D: 663 - 759 (UniProt: P08487)
PDBExternal DatabaseDetails
Gly 659-expression tag
Ser 660-expression tag
His 661-expression tag
Met 662-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight53980.5
All*Total formula weight53980.5
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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