2CIA
human nck2 sh2-domain in complex with a decaphosphopeptide from translocated intimin receptor (tir) of epec
Summary for 2CIA
Entry DOI | 10.2210/pdb2cia/pdb |
Related | 1WX6 1Z3K 2CI9 |
Descriptor | CYTOPLASMIC PROTEIN NCK2, TRANSLOCATED INTIMIN RECEPTOR, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total) |
Functional Keywords | sh2-domain, sh3 domain, phosphorylation, binding specificity |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 13093.56 |
Authors | Frese, S.,Schubert, W.-D.,Findeis, A.C.,Marquardt, T.,Roske, Y.S.,Stradal, T.E.B.,Heinz, D.W. (deposition date: 2006-03-17, release date: 2006-04-24, Last modification date: 2024-05-01) |
Primary citation | Frese, S.,Schubert, W.-D.,Findeis, A.C.,Marquardt, T.,Roske, Y.S.,Stradal, T.E.B.,Heinz, D.W. The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains. J.Biol.Chem., 281:18236-, 2006 Cited by PubMed: 16636066DOI: 10.1074/JBC.M512917200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
Download full validation report