2BBU
solution structure of mouse socs3 in complex with a phosphopeptide from the gp130 receptor
Summary for 2BBU
Entry DOI | 10.2210/pdb2bbu/pdb |
NMR Information | BMRB: 6580 |
Descriptor | Suppressor of cytokine signaling 3, GP130 PHOSPHOPEPTIDE (2 entities in total) |
Functional Keywords | sh2 domain, extended sh2 subdomain, pest motif, protein complex, phosphopeptide, cytokine regulator |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 19566.81 |
Authors | Babon, J.J.,Yao, S.,Norton, R.S. (deposition date: 2005-10-17, release date: 2006-05-02, Last modification date: 2022-03-09) |
Primary citation | Babon, J.J.,McManus, E.J.,Yao, S.,DeSouza, D.P.,Mielke, L.A.,Sprigg, N.S.,Willson, T.A.,Hilton, D.J.,Nicola, N.A.,Baca, M.,Nicholson, S.E.,Norton, R.S. The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability Mol.Cell, 22:205-216, 2006 Cited by PubMed: 16630890DOI: 10.1016/j.molcel.2006.03.024 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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