8Q99
 
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8Q2L
 | | Tau - AD-MIA4 | | 分子名称: | Isoform Tau-D of Microtubule-associated protein tau | | 著者 | Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. | | 登録日 | 2023-08-02 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
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8Q8Z
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8Q98
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8QJJ
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7R5H
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7U0Z
 | | High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1 | | 分子名称: | Isoform Tau-E of Microtubule-associated protein tau | | 著者 | FItzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | | 登録日 | 2022-02-19 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
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5ZV3
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6BB4
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6H0E
 | | FAB dmCBTAU-22.1 IN COMPLEX WITH TAU PEPTIDE V1088-23 | | 分子名称: | GLYCEROL, HUMAN FAB ANTIBODY FRAGMENT OF dmCBTAU-22.1, Microtubule-associated protein tau | | 著者 | Juraszek, J, Steinbacher, S. | | 登録日 | 2018-07-09 | | 公開日 | 2018-07-25 | | 最終更新日 | 2020-03-11 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Enhancement of therapeutic potential of a naturally occurring human antibody targeting a phosphorylated Ser422containing epitope on pathological tau.
Acta Neuropathol Commun, 6, 2018
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6QJP
 | | Cryo-EM structure of heparin-induced 2N4R tau jagged filaments | | 分子名称: | Microtubule-associated protein tau | | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | | 登録日 | 2019-01-24 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
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6QJH
 | | Cryo-EM structure of heparin-induced 2N4R tau snake filaments | | 分子名称: | Microtubule-associated protein tau | | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | | 登録日 | 2019-01-24 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
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6QJM
 | | Cryo-EM structure of heparin-induced 2N4R tau twister filaments | | 分子名称: | Microtubule-associated protein tau | | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | | 登録日 | 2019-01-24 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
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6QJQ
 | | Cryo-EM structure of heparin-induced 2N3R tau filaments | | 分子名称: | Microtubule-associated protein tau | | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | | 登録日 | 2019-01-24 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
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5MO3
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5MP5
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5MP1
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7YPG
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7YMN
 | | Cryo-EM structure of in vitro PHF fibril | | 分子名称: | Isoform Tau-D of Microtubule-associated protein tau | | 著者 | Li, X, Liu, C. | | 登録日 | 2022-07-28 | | 公開日 | 2022-12-14 | | 最終更新日 | 2022-12-28 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure.
Iscience, 25, 2022
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5N5B
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5N5A
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5O3L
 | | Paired helical filament in Alzheimer's disease brain | | 分子名称: | Microtubule-associated protein tau | | 著者 | Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W. | | 登録日 | 2017-05-24 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
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6TJO
 | | Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration | | 分子名称: | Microtubule-associated protein tau | | 著者 | Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W. | | 登録日 | 2019-11-26 | | 公開日 | 2020-02-05 | | 最終更新日 | 2020-04-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
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6TJX
 | | Cryo-EM structure of TypeII tau filaments extracted from the brains of individuals with Corticobasal degeneration | | 分子名称: | Microtubule-associated protein tau | | 著者 | Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W. | | 登録日 | 2019-11-27 | | 公開日 | 2020-02-05 | | 最終更新日 | 2020-04-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
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5O3O
 | | Pronase-treated paired helical filament in Alzheimer's disease brain | | 分子名称: | Microtubule-associated protein tau | | 著者 | Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W. | | 登録日 | 2017-05-24 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
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