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PDB: 214 results

7NRQ
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BU of 7nrq by Molmil
Paired helical filament from primary age-related tauopathy brain
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
Deposit date:2021-03-04
Release date:2021-03-24
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRT
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BU of 7nrt by Molmil
Conformation 2 of straight filament from primary age-related tauopathy brain
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
Deposit date:2021-03-04
Release date:2021-03-24
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRX
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BU of 7nrx by Molmil
Straight filament from Alzheimer's disease with PET ligand APN-1607
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
Deposit date:2021-03-04
Release date:2021-03-24
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRS
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BU of 7nrs by Molmil
Conformation 1 of straight filament from primary age-related tauopathy brain
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
Deposit date:2021-03-04
Release date:2021-03-24
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7P66
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BU of 7p66 by Molmil
Globular glial tauopathy type 1 tau filament
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure-based classification of tauopathies.
Nature, 598, 2021
7P6A
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BU of 7p6a by Molmil
Limbic-predominant neuronal inclusion body 4R tauopathy type 1a tau filament
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (1.9 Å)
Cite:Structure-based classification of tauopathies.
Nature, 598, 2021
7P6E
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BU of 7p6e by Molmil
Argyrophilic grain disease type 2 tau filament
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure-based classification of tauopathies.
Nature, 598, 2021
7P68
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BU of 7p68 by Molmil
Globular glial tauopathy type 3 tau filament
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure-based classification of tauopathies.
Nature, 598, 2021
7P6D
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BU of 7p6d by Molmil
Argyrophilic grain disease type 1 tau filament
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure-based classification of tauopathies.
Nature, 598, 2021
7P65
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BU of 7p65 by Molmil
Progressive supranuclear palsy tau filament
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure-based classification of tauopathies.
Nature, 598, 2021
7P6C
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BU of 7p6c by Molmil
Limbic-predominant neuronal inclusion body 4R tauopathy type 2 tau filament
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structure-based classification of tauopathies.
Nature, 598, 2021
7P67
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BU of 7p67 by Molmil
Globular glial tauopathy type 2 tau filament
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure-based classification of tauopathies.
Nature, 598, 2021
7P6B
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BU of 7p6b by Molmil
Limbic-predominant neuronal inclusion body 4R tauopathy type 1b tau filament
Descriptor: Microtubule-associated protein tau
Authors:Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Structure-based classification of tauopathies.
Nature, 598, 2021
6DCA
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BU of 6dca by Molmil
Fab/epitope complex of mouse monoclonal antibody 6B2 targeting a non-phosphorylated tau epitope.
Descriptor: Fab heavy chain, Fab light chain, Microtubule-associated protein tau, ...
Authors:Chukwu, J.E, Kong, X.-P.
Deposit date:2018-05-04
Release date:2019-03-20
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.599 Å)
Cite:Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein.
MAbs, 11, 2019
6DC9
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BU of 6dc9 by Molmil
Fab/epitope complex of human chimeric monoclonal antibody h4E6 targeting a phosphorylated tau epitope.
Descriptor: Fab heavy chain, Fab light chain, GLYCEROL, ...
Authors:Chukwu, J.E, Kong, X.-P.
Deposit date:2018-05-04
Release date:2019-03-20
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.999 Å)
Cite:Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein.
MAbs, 11, 2019
6DC8
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BU of 6dc8 by Molmil
Fab/epitope complex of mouse monoclonal antibody 8B2 targeting a non-phosphorylated tau epitope.
Descriptor: GLYCEROL, IgG heavy chain, IgG light chain, ...
Authors:Chukwu, J.E, Kong, X.-P.
Deposit date:2018-05-04
Release date:2019-03-20
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein.
MAbs, 11, 2019
7QJW
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BU of 7qjw by Molmil
In vitro assembled tau filaments with structures like chronic traumatic encephalopathy type II (8a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-01-19
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKF
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BU of 7qkf by Molmil
In vitro assembled 266/297 - 391 tau filaments with CuCl2 (12a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QJV
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BU of 7qjv by Molmil
In vitro assembled tau filaments into Quadruple Helical Filaments type 1 (2c)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QL3
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BU of 7ql3 by Molmil
in vitro assembled 266/297 - 391 tau filaments with NaCl (8b)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QJY
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BU of 7qjy by Molmil
In vitro assembled 266/297 - 391 tau filaments with LiCl (9a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKW
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BU of 7qkw by Molmil
In vitro assembled 266-391 S356D tau filaments with KCl (44a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.32 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QK3
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BU of 7qk3 by Molmil
In vitro assembled 258-391 tau filaments, 700 rpm (38a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QK2
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BU of 7qk2 by Molmil
In vitro assembled 300-391 tau filaments in PBS (36a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QL1
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BU of 7ql1 by Molmil
In vitro assembled 266-391 tau filaments in PBS (23a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022

220113

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