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PDB: 522 results

2SEM
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BU of 2sem by Molmil
SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR
Descriptor: PROTEIN (SEX MUSCLE ABNORMAL PROTEIN 5), PROTEIN (SH3 PEPTOID INHIBITOR)
Authors:Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A.
Deposit date:1998-11-02
Release date:1999-01-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.
Science, 282, 1998
2RN8
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BU of 2rn8 by Molmil
NMR structure note: murine Itk SH3 domain
Descriptor: Tyrosine-protein kinase ITK/TSK
Authors:Severin, A.J.
Deposit date:2007-12-08
Release date:2007-12-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure note: murine Itk SH3 domain
To be Published
2ROT
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BU of 2rot by Molmil
Structure of chimeric variant of SH3 domain- SHH
Descriptor: Spectrin alpha chain, brain
Authors:Kutyshenko, N.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V.
Deposit date:2008-04-10
Release date:2009-04-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the chimeric SH3 domains, SHH- and SHA-"Bergeracs".
Biochim.Biophys.Acta, 1794, 2009
2V1R
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BU of 2v1r by Molmil
Yeast Pex13 SH3 domain complexed with a peptide from Pex14 at 2.1 A resolution
Descriptor: PEROXISOMAL MEMBRANE PROTEIN PAS20, PEX14
Authors:Kursula, I, Kursula, P, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M.
Deposit date:2007-05-29
Release date:2008-06-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Genomics of Yeast SH3 Domains
To be Published
2VKN
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BU of 2vkn by Molmil
YEAST SHO1 SH3 DOMAIN COMPLEXED WITH A PEPTIDE FROM PBS2
Descriptor: MAP KINASE KINASE PBS2, PROTEIN SSU81, SULFATE ION
Authors:Kursula, P, Kursula, I, Song, Y.H, Paraskevopoulos, K, Wilmanns, M.
Deposit date:2007-12-20
Release date:2008-02-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Genomics of Yeast SH3 Domains
To be Published
2V1Q
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BU of 2v1q by Molmil
Atomic-resolution structure of the yeast Sla1 SH3 domain 3
Descriptor: CHLORIDE ION, CYTOSKELETON ASSEMBLY CONTROL PROTEIN SLA1, PLATINUM (II) ION, ...
Authors:Kursula, I, Kursula, P, Zou, P, Lehmann, F, Song, Y.H, Wilmanns, M.
Deposit date:2007-05-29
Release date:2008-06-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural Genomics of Yeast SH3 Domains
To be Published
2W10
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BU of 2w10 by Molmil
Mona SH3C in complex
Descriptor: GRB2-RELATED ADAPTOR PROTEIN 2, PHOSPHATE ION, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23
Authors:Harkiolaki, M, Feller, S.M.
Deposit date:2008-10-13
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2VWF
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BU of 2vwf by Molmil
Grb2 SH3C (2)
Descriptor: GRB2-ASSOCIATED-BINDING PROTEIN 2, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Harkiolaki, M, Tsirka, T, Feller, S.M.
Deposit date:2008-06-24
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2VVK
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BU of 2vvk by Molmil
Grb2 SH3C (1)
Descriptor: GLYCEROL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Harkiolaki, M, Tsirka, T, Feller, S.M.
Deposit date:2008-06-09
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2W0Z
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BU of 2w0z by Molmil
Grb2 SH3C (3)
Descriptor: GRB2-ASSOCIATED-BINDING PROTEIN 2, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Harkiolaki, M, Tsirka, T, Feller, S.M.
Deposit date:2008-10-13
Release date:2009-05-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2XMF
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BU of 2xmf by Molmil
Myosin 1e SH3
Descriptor: MYOSIN 1E SH3, OCTANE 1,8-DIAMINE
Authors:Edwards, T, Allsop, G, Peckham, M.
Deposit date:2010-07-27
Release date:2011-08-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Myosin 1E SH3
To be Published
5NP5
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BU of 5np5 by Molmil
Abl2 SH3 pTyr116/161
Descriptor: Abelson tyrosine-protein kinase 2, SULFATE ION
Authors:Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5NP2
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BU of 5np2 by Molmil
Abl1 SH3 pTyr89/134
Descriptor: Tyrosine-protein kinase ABL1
Authors:Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5O2P
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BU of 5o2p by Molmil
p130Cas SH3 domain PTP-PEST peptide chimera
Descriptor: Breast cancer anti-estrogen resistance 1,Tyrosine-protein phosphatase non-receptor type 12
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5OAZ
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BU of 5oaz by Molmil
Crystal structure of the Abl-SH3 domain at pH 7.5
Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:Crystal structure of the Abl-SH3 domain at pH 7.5
to be published
5OB0
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BU of 5ob0 by Molmil
Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.172 Å)
Cite:Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12
to be published
5OB2
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BU of 5ob2 by Molmil
Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
to be published
5OAV
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BU of 5oav by Molmil
High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-23
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
to be published
5OB1
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BU of 5ob1 by Molmil
Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.172 Å)
Cite:Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12
to be published
5O2Q
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BU of 5o2q by Molmil
p130Cas SH3 domain Vinculin peptide chimera
Descriptor: Breast cancer anti-estrogen resistance 1,Vinculin
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5O2M
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BU of 5o2m by Molmil
p130Cas SH3 domain
Descriptor: Breast cancer anti-estrogen resistance 1
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5QU6
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BU of 5qu6 by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.8A, triclinic
Descriptor: Cytoplasmic protein NCK1
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.816 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU8
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BU of 5qu8 by Molmil
Crystal Structure of symmetric swapped human Nck SH3.1 domain, 0.93A, orthorhombic form IV
Descriptor: Cytoplasmic protein NCK1, SODIUM ION
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU3
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BU of 5qu3 by Molmil
Crystal Structure of domain swapped human Nck SH3.1, 1.01A, monoclinic
Descriptor: Cytoplasmic protein NCK1
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QUA
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BU of 5qua by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.5A, C2221
Descriptor: Cytoplasmic protein NCK1
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020

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