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PDB: 9 results

4GGD
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BU of 4ggd by Molmil
Structural analysis of human Cdc20 supports multisite degron recognition by APC/C.
Descriptor: Cell division cycle protein 20 homolog, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Authors:Luo, X, Tian, W, Tomchick, D.R.
Deposit date:2012-08-06
Release date:2012-11-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.435 Å)
Cite:Structural analysis of human Cdc20 supports multisite degron recognition by APC/C.
Proc.Natl.Acad.Sci.USA, 109, 2012
6TLJ
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BU of 6tlj by Molmil
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Alfieri, C, Barford, D.
Deposit date:2019-12-02
Release date:2020-02-19
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase.
Embo Rep., 21, 2020
2WVI
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BU of 2wvi by Molmil
Crystal Structure of the N-terminal Domain of BubR1
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 BETA, ...
Authors:D'Arcy, S, Davies, O.R, Blundell, T.L, Bolanos-Garcia, V.M.
Deposit date:2009-10-16
Release date:2010-03-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Defining the Molecular Basis of Bubr1 Kinetochore Interactions and Anaphase-Promoting Complex/Cyclosome (Apc/C)-Cdc20 Inhibition
J.Biol.Chem., 285, 2010
5SWF
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The structure of the PP2A B56 subunit double phosphorylated BubR1 complex
Descriptor: Double phosphorylated BubR1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Authors:Page, R, Wang, X, Bajaj, R, Peti, W.
Deposit date:2016-08-08
Release date:2016-11-30
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.818 Å)
Cite:Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
Structure, 24, 2016
3SI5
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BU of 3si5 by Molmil
Kinetochore-BUBR1 kinase complex
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Protein CASC5
Authors:Blundell, T.L, Chirgadze, D.Y, Bolanos-Garcia, V.M.
Deposit date:2011-06-17
Release date:2011-10-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site.
Structure, 19, 2011
5K6S
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BU of 5k6s by Molmil
The structure of the PP2A B56 subunit BubR1 complex
Descriptor: BubR1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Authors:Page, R, Wang, X, Bajaj, R, Peti, W.
Deposit date:2016-05-25
Release date:2016-12-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.794 Å)
Cite:Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
Structure, 24, 2016
5KHU
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BU of 5khu by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Yamaguchi, M, VanderLinden, R, Dube, P, Stark, H, Schulman, B.
Deposit date:2016-06-15
Release date:2016-09-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol.Cell, 63, 2016
5LCW
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BU of 5lcw by Molmil
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Alfieri, C, Chang, L, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D.
Deposit date:2016-06-22
Release date:2016-08-10
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Molecular basis of APC/C regulation by the spindle assembly checkpoint.
Nature, 536, 2016
5JJA
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Crystal structure of a PP2A B56gamma/BubR1 complex
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Authors:Wang, Z, Wang, J, Rao, Z, Xu, W.
Deposit date:2016-04-22
Release date:2016-07-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization.
Protein Cell, 7, 2016

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