2WVI
Crystal Structure of the N-terminal Domain of BubR1
Summary for 2WVI
Entry DOI | 10.2210/pdb2wvi/pdb |
Descriptor | MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 BETA, PRASEODYMIUM ION, ACETATE ION, ... (5 entities in total) |
Functional Keywords | tumor suppressor, mitotic checkpoint, tpr, kinase, apoptosis, serine/threonine-protein kinase, cell division, cell cycle, kinetochore, transferase, cytoskeleton |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: O60566 |
Total number of polymer chains | 1 |
Total formula weight | 20062.68 |
Authors | D'Arcy, S.,Davies, O.R.,Blundell, T.L.,Bolanos-Garcia, V.M. (deposition date: 2009-10-16, release date: 2010-03-09, Last modification date: 2024-05-08) |
Primary citation | D'Arcy, S.,Davies, O.R.,Blundell, T.L.,Bolanos-Garcia, V.M. Defining the Molecular Basis of Bubr1 Kinetochore Interactions and Anaphase-Promoting Complex/Cyclosome (Apc/C)-Cdc20 Inhibition J.Biol.Chem., 285:14764-, 2010 Cited by PubMed: 20220147DOI: 10.1074/JBC.M109.082016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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