3U23
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u23 by Molmil](/molmil-images/mine/3u23) | Atomic resolution crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide from human RIN3 | Descriptor: | 1,2-ETHANEDIOL, CD2-associated protein, Ras and Rab interactor 3 | Authors: | Simister, P.C, Rouka, E, Janning, M, Muniz, J.R.C, Kirsch, K.H, Knapp, S, von Delft, F, Filippakopoulos, P, Arrowsmith, C.H, Krojer, T, Edwards, A.M, Weigelt, J, Bountra, C, Feller, S.M, Structural Genomics Consortium (SGC) | Deposit date: | 2011-09-30 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.11 Å) | Cite: | Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3). J.Biol.Chem., 290, 2015
|
|
4X1V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4x1v by Molmil](/molmil-images/mine/4x1v) | Crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 76-91) from human ARAP1 | Descriptor: | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1, CD2-associated protein | Authors: | Rouka, E, Krojer, T, von Delft, F, Knapp, S, Kirsch, K.H, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Feller, S.M, Simister, P.C. | Deposit date: | 2014-11-25 | Release date: | 2016-02-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 76-91) from human ARAP1 to be published
|
|
1M4J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m4j by Molmil](/molmil-images/mine/1m4j) | CRYSTAL STRUCTURE OF THE N-TERMINAL ADF-H DOMAIN OF MOUSE TWINFILIN ISOFORM-1 | Descriptor: | A6 gene product | Authors: | Paavilainen, V.O, Merckel, M.C, Falck, S, Ojala, P.J, Pohl, E, Wilmanns, M, Lappalainen, P. | Deposit date: | 2002-07-03 | Release date: | 2002-11-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Conservation Between the Actin Monomer-binding Sites of Twinfilin and Actin-depolymerizing Factor (ADF)/Cofilin J.Biol.Chem., 277, 2002
|
|
4WCI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wci by Molmil](/molmil-images/mine/4wci) | Crystal structure of the 1st SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 378-393) from human RIN3 | Descriptor: | CD2-associated protein, Ras and Rab interactor 3, SULFATE ION | Authors: | Rouka, E, Simister, P.C, Janning, M, Kirsch, K.H, Krojer, T, Knapp, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Feller, S.M, Structural Genomics Consortium (SGC) | Deposit date: | 2014-09-04 | Release date: | 2015-08-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3). J.Biol.Chem., 290, 2015
|
|
7DS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ds6 by Molmil](/molmil-images/mine/7ds6) | |
2J6F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2j6f by Molmil](/molmil-images/mine/2j6f) | N-TERMINAL SH3 DOMAIN OF CMS (CD2AP HUMAN HOMOLOG) BOUND TO CBL-B PEPTIDE | Descriptor: | CD2-ASSOCIATED PROTEIN, E3 UBIQUITIN-PROTEIN LIGASE CBL-B | Authors: | Moncalian, G, Cardenes, N, Deribe, Y.L, Spinola-Amilibia, M, Dikic, I, Bravo, J. | Deposit date: | 2006-09-28 | Release date: | 2006-10-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Atypical Polyproline Recognition by the Cms N- Terminal SH3 Domain. J.Biol.Chem., 281, 2006
|
|
7DS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ds4 by Molmil](/molmil-images/mine/7ds4) | |
3AA6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3aa6 by Molmil](/molmil-images/mine/3aa6) | Crystal structure of Actin capping protein in complex with the Cp-binding motif derived from CD2AP | Descriptor: | 23mer peptide from CD2-associated protein, BARIUM ION, F-actin-capping protein subunit alpha-1, ... | Authors: | Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y. | Deposit date: | 2009-11-11 | Release date: | 2010-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition Plos Biol., 8, 2010
|
|
6RSW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rsw by Molmil](/molmil-images/mine/6rsw) | HFD domain of mouse CAP1 bound to the pointed end of G-actin | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Kotila, T, Kogan, K, Lappalainen, P. | Deposit date: | 2019-05-22 | Release date: | 2019-11-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin. Nat Commun, 10, 2019
|
|
7DS8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ds8 by Molmil](/molmil-images/mine/7ds8) | |
7DS2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ds2 by Molmil](/molmil-images/mine/7ds2) | |
3LK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lk4 by Molmil](/molmil-images/mine/3lk4) | Crystal structure of CapZ bound to the uncapping motif from CD2AP | Descriptor: | CD2-associated protein, F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2 | Authors: | Hernandez-Valladares, M, Kim, T, Kannan, B, Tung, A, Cooper, J.A, Robinson, R.C. | Deposit date: | 2010-01-27 | Release date: | 2010-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural characterization of a capping protein interaction motif defines a family of actin filament regulators. Nat.Struct.Mol.Biol., 17, 2010
|
|
2J6O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2j6o by Molmil](/molmil-images/mine/2j6o) | ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETEROTRIMER | Descriptor: | CD2-ASSOCIATED PROTEIN, T-CELL SURFACE ANTIGEN CD2 | Authors: | Moncalian, G, Cardenes, N, Deribe, Y.L, Spinola-Amilibia, M, Dikic, I, Bravo, J. | Deposit date: | 2006-10-02 | Release date: | 2006-10-11 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Atypical Polyproline Recognition by the Cms N-Terminal SH3 Domain. J.Biol.Chem., 281, 2006
|
|
7DSB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dsb by Molmil](/molmil-images/mine/7dsb) | |
3DAW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3daw by Molmil](/molmil-images/mine/3daw) | Structure of the actin-depolymerizing factor homology domain in complex with actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Paavilainen, V.O, Oksanen, E, Goldman, A, Lappalainen, P. | Deposit date: | 2008-05-30 | Release date: | 2008-07-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structure of the actin-depolymerizing factor homology domain in complex with actin J.Cell Biol., 182, 2008
|
|
6YP9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yp9 by Molmil](/molmil-images/mine/6yp9) | Rabbit muscle actin in complex with ADF-H and ATP-ATTO-488 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Kogan, K, Kotila, T, Lappalainen, P. | Deposit date: | 2020-04-15 | Release date: | 2020-12-09 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.564 Å) | Cite: | A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics. Nat Commun, 12, 2021
|
|
2J6K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2j6k by Molmil](/molmil-images/mine/2j6k) | N-TERMINAL SH3 DOMAIN OF CMS (CD2AP HUMAN HOMOLOG) | Descriptor: | CD2-ASSOCIATED PROTEIN, SODIUM ION | Authors: | Moncalian, G, Cardenes, N, Deribe, Y.L, Spinola-Amilibia, M, Dikic, I, Bravo, J. | Deposit date: | 2006-09-29 | Release date: | 2006-10-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Atypical Polyproline Recognition by the Cms N- Terminal SH3 Domain. J.Biol.Chem., 281, 2006
|
|
2J7I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2j7i by Molmil](/molmil-images/mine/2j7i) | ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETERODIMER | Descriptor: | CD2-ASSOCIATED PROTEIN, T-CELL SURFACE ANTIGEN CD2 | Authors: | Moncalian, G, Cardenes, N, Deribe, Y.L, Spinola-Amilibia, M, Dikic, I, Bravo, J. | Deposit date: | 2006-10-09 | Release date: | 2006-11-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Atypical Polyproline Recognition by the Cms N-Terminal Src Homology 3 Domain. J.Biol.Chem., 281, 2006
|
|
2HD7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hd7 by Molmil](/molmil-images/mine/2hd7) | Solution structure of C-teminal domain of twinfilin-1. | Descriptor: | Twinfilin-1 | Authors: | Hellman, M.H, Paavilainen, V.O, Annila, A, Lappalainen, P, Permi, P.I. | Deposit date: | 2006-06-20 | Release date: | 2007-02-06 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural basis and evolutionary origin of actin filament capping by twinfilin Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2FEI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fei by Molmil](/molmil-images/mine/2fei) | Solution structure of the second SH3 domain of Human CMS protein | Descriptor: | CD2-associated protein | Authors: | Yao, B, Dai, H, Jiao, Y, Wu, J, Shi, Y. | Deposit date: | 2005-12-15 | Release date: | 2006-12-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the second SH3 domain of human CMS and a newly identified binding site at the C-terminus of c-Cbl Biochim.Biophys.Acta, 1774, 2007
|
|
2D8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2d8b by Molmil](/molmil-images/mine/2d8b) | Solution structure of the second tandem cofilin-domain of mouse twinfilin | Descriptor: | Twinfilin-1 | Authors: | Goroncy, A.K, Kigawa, T, Koshiba, S, Sato, M, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-12-02 | Release date: | 2006-06-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR solution structures of actin depolymerizing factor homology domains Protein Sci., 18, 2009
|
|