4X1V

Crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 76-91) from human ARAP1

Summary for 4X1V

• Entry DOI: 10.2210/pdb4x1v/pdb
• Related: 3U23 4WCI
• Descriptor: CD2-associated protein, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (3 entities in total)
• Functional Keywords: endocytosis adaptor protein, protein-peptide binary complex, kidney, signaling protein, structural genomics consortium, sgc
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm, cytoskeleton : Q9Y5K6; Cytoplasm: Q96P48
• Total number of polymer chains: 2
• Total formula weight: 9425.78

Authors

Rouka, E.,Krojer, T.,von Delft, F.,Knapp, S.,Kirsch, K.H.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Feller, S.M.,Simister, P.C. (deposition date: 2014-11-25, release date: 2016-02-17, Last modification date: 2016-02-24)

• Primary citation: Rouka, E.,Feller, S.M.,Simister, P.C.; Crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 76-91) from human ARAP1; to be published,

Experimental method

X-RAY DIFFRACTION (1.58 Å)