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PDB: 8 results

4CU4
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BU of 4cu4 by Molmil
FhuA from E. coli in complex with the lasso peptide microcin J25 (MccJ25)
Descriptor: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 3-HYDROXY-TETRADECANOIC ACID, DIPHOSPHATE, ...
Authors:Mathavan, I, Rebuffat, S, Beis, K.
Deposit date:2014-03-17
Release date:2014-04-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Hijacking Siderophore Receptors by Antimicrobial Lasso Peptides.
Nat.Chem.Biol., 10, 2014
6N60
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BU of 6n60 by Molmil
Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Microcin J25 (MccJ25)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A.
Deposit date:2018-11-23
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.68 Å)
Cite:Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
1S7P
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Solution structure of thermolysin digested microcin J25
Descriptor: microcin J25
Authors:Rosengren, K.J, Blond, A, Afonso, C, Tabet, J.C, Rebuffat, S, Craik, D.J.
Deposit date:2004-01-30
Release date:2004-06-15
Last modified:2011-07-27
Method:SOLUTION NMR
Cite:Structure of thermolysin cleaved microcin J25: extreme stability of a two-chain antimicrobial peptide devoid of covalent links
Biochemistry, 43, 2004
2MMW
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LASSO PEPTIDE BASED INTEGRIN INHIBITOR: MICROCIN J25 VARIANT WITH RGD SUBSTITUTION of GLY12-ILE13-GLY14
Descriptor: Microcin J25
Authors:Knappe, T.A, Linne, U, Xie, X, Marahiel, M.A.
Deposit date:2014-03-20
Release date:2014-05-14
Method:SOLUTION NMR
Cite:Introducing lasso peptides as molecular scaffolds for drug design: engineering of an integrin antagonist.
Angew.Chem.Int.Ed.Engl., 50, 2011
2MMT
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BU of 2mmt by Molmil
Lasso peptide-based integrin inhibitor: Microcin J25 variant with RGDF substitution of Gly12-Ile13-Gly14-Thr15
Descriptor: Microcin J25 RGDF mutant
Authors:Hegemann, J.D, Zimmermann, M, Knappe, T.A, Xie, X, Marahiel, M.A.
Deposit date:2014-03-18
Release date:2014-07-02
Last modified:2014-07-23
Method:SOLUTION NMR
Cite:Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides.
J.Med.Chem., 57, 2014
1PP5
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BU of 1pp5 by Molmil
Structure of Antibacterial Peptide Microcin J25: a 21-Residue Lariat Protoknot
Descriptor: microcin J25
Authors:Bayro, M.J, Swapna, G.V.T, Huang, J.Y, Ma, L.-C, Mukhopadhyay, J, Ebright, R.H, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2003-06-16
Release date:2003-10-28
Last modified:2012-12-12
Method:SOLUTION NMR
Cite:Structure of Antibacterial Peptide Microcin J25: A 21-Residue Lariat Protoknot.
J.Am.Chem.Soc., 125, 2003
5T56
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BU of 5t56 by Molmil
[3]catenane from MccJ25 G12R/I13C/G21C lasso peptide
Descriptor: Microcin J25
Authors:Link, A.J, Allen, C.D.
Deposit date:2016-08-30
Release date:2017-07-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Self-Assembly of Catenanes from Lasso Peptides.
J. Am. Chem. Soc., 138, 2016
1Q71
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The structure of microcin J25 is a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone
Descriptor: microcin J25
Authors:Rosengren, K.J, Clark, R, Daly, N.L, Goransson, U, Jones, A, Craik, D.J.
Deposit date:2003-08-14
Release date:2003-12-16
Last modified:2012-12-12
Method:SOLUTION NMR
Cite:Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone.
J.Am.Chem.Soc., 125, 2003

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