7ZK3
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![BU of 7zk3 by Molmil](/molmil-images/mine/7zk3) | Structure of 1PBC- and calcium-bound mTMEM16A(ac) chloride channel at 2.85 A resolution | Descriptor: | 1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile, Anoctamin-1, CALCIUM ION | Authors: | Lam, A.K.M, Rutz, S, Dutzler, R. | Deposit date: | 2022-04-12 | Release date: | 2022-05-25 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC. Nat Commun, 13, 2022
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8QZC
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![BU of 8qzc by Molmil](/molmil-images/mine/8qzc) | |
7B5D
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![BU of 7b5d by Molmil](/molmil-images/mine/7b5d) | |
7B5C
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![BU of 7b5c by Molmil](/molmil-images/mine/7b5c) | Structure of calcium-bound mTMEM16A(ac) chloride channel at 3.7 A resolution | Descriptor: | Anoctamin-1, CALCIUM ION | Authors: | Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R. | Deposit date: | 2020-12-03 | Release date: | 2021-02-10 | Last modified: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Gating the pore of the calcium-activated chloride channel TMEM16A. Nat Commun, 12, 2021
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5OYB
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![BU of 5oyb by Molmil](/molmil-images/mine/5oyb) | Structure of calcium-bound mTMEM16A chloride channel at 3.75 A resolution | Descriptor: | Anoctamin-1, CALCIUM ION | Authors: | Paulino, C, Kalienkova, V, Lam, K.M, Neldner, Y, Dutzler, R. | Deposit date: | 2017-09-08 | Release date: | 2017-12-20 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM. Nature, 552, 2017
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6BGJ
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![BU of 6bgj by Molmil](/molmil-images/mine/6bgj) | Cryo-EM structure of the TMEM16A calcium-activated chloride channel in LMNG | Descriptor: | Anoctamin-1, CALCIUM ION | Authors: | Dang, S, Feng, S, Tien, J, Peters, C.J, Bulkley, D, Lolicato, M, Zhao, J, Zuberbuhler, K, Ye, W, Qi, L, Chen, T, Craik, C.S, Jan, Y.N, Minor Jr, D.L, Cheng, Y, Jan, L.Y. | Deposit date: | 2017-10-28 | Release date: | 2017-12-27 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structures of the TMEM16A calcium-activated chloride channel. Nature, 552, 2017
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6BGI
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![BU of 6bgi by Molmil](/molmil-images/mine/6bgi) | Cryo-EM structure of the TMEM16A calcium-activated chloride channel in nanodisc | Descriptor: | Anoctamin-1, CALCIUM ION | Authors: | Dang, S, Feng, S, Tien, J, Peters, C.J, Bulkley, D, Lolicato, M, Zhao, J, Zuberbuhler, K, Ye, W, Qi, J, Chen, T, Craik, C.S, Jan, Y.N, Minor Jr, D.L, Cheng, Y, Jan, L.Y. | Deposit date: | 2017-10-28 | Release date: | 2017-12-27 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structures of the TMEM16A calcium-activated chloride channel. Nature, 552, 2017
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5OYG
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![BU of 5oyg by Molmil](/molmil-images/mine/5oyg) | Structure of calcium-free mTMEM16A chloride channel at 4.06 A resolution | Descriptor: | Anoctamin-1 | Authors: | Paulino, C, Kalienkova, V, Lam, K.M, Neldner, Y, Dutzler, R. | Deposit date: | 2017-09-08 | Release date: | 2017-12-20 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.06 Å) | Cite: | Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM. Nature, 552, 2017
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7B5E
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![BU of 7b5e by Molmil](/molmil-images/mine/7b5e) | Structure of calcium-bound mTMEM16A(ac)-I551A chloride channel at 4.1 A resolution | Descriptor: | Anoctamin-1, CALCIUM ION | Authors: | Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R. | Deposit date: | 2020-12-03 | Release date: | 2021-02-10 | Last modified: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Gating the pore of the calcium-activated chloride channel TMEM16A. Nat Commun, 12, 2021
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5NL2
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![BU of 5nl2 by Molmil](/molmil-images/mine/5nl2) | cryo-EM structure of the mTMEM16A ion channel at 6.6 A resolution. | Descriptor: | Anoctamin-1 | Authors: | Paulino, C, Neldner, Y, Lam, K.M, Kalienkova, V, Brunner, J.D, Schenck, S, Dutzler, R. | Deposit date: | 2017-04-03 | Release date: | 2017-06-07 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A. Elife, 6, 2017
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