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PDB: 9 results

1VF7
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BU of 1vf7 by Molmil
Crystal structure of the membrane fusion protein, MexA of the multidrug transporter
Descriptor: Multidrug resistance protein mexA
Authors:Akama, H, Matsuura, T, Kashiwagi, S, Yoneyama, H, Tsukihara, T, Nakagawa, A, Nakae, T.
Deposit date:2004-04-09
Release date:2004-05-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the membrane fusion protein, MexA, of the multidrug transporter in Pseudomonas aeruginosa
J.Biol.Chem., 279, 2004
1T5E
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BU of 1t5e by Molmil
The structure of MexA
Descriptor: D-Glyceraldehyde, GLYCEROL, Multidrug resistance protein mexA
Authors:Higgins, M.K, Bokma, E, Koronakis, E, Hughes, C, Koronakis, V.
Deposit date:2004-05-04
Release date:2004-05-18
Last modified:2020-07-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the periplasmic component of a bacterial drug efflux pump
Proc.Natl.Acad.Sci.USA, 101, 2004
2V4D
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BU of 2v4d by Molmil
Re-refinement of MexA adaptor protein
Descriptor: MULTIDRUG RESISTANCE PROTEIN MEXA, SULFATE ION
Authors:Symmons, M.F, Bokma, E, Koronakis, E, Hughes, C, Koronakis, V.
Deposit date:2008-09-18
Release date:2009-04-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Assembled Structure of a Complete Tripartite Bacterial Multidrug Efflux Pump.
Proc.Natl.Acad.Sci.USA, 106, 2009
6TA6
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BU of 6ta6 by Molmil
MexAB assembly of the Pseudomonas MexAB-OprM efflux pump reconstituted in nanodiscs
Descriptor: Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM
Authors:Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I.
Deposit date:2019-10-29
Release date:2020-09-16
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex.
Nat Commun, 11, 2020
6TA5
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BU of 6ta5 by Molmil
OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs
Descriptor: Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM
Authors:Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I.
Deposit date:2019-10-29
Release date:2020-09-16
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex.
Nat Commun, 11, 2020
4DK1
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Crystal Structure of MacA-MexA chimeric protein, containing the Pseudomonas aeruginosa MexA alpha-hairpin domain.
Descriptor: Putative MacA, Multidrug resistance protein mexA
Authors:Xu, Y, Ha, N.C.
Deposit date:2012-02-03
Release date:2012-03-07
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3.499 Å)
Cite:Assembly and channel opening of outer membrane protein in tripartite drug efflux pumps of Gram-negative bacteria.
J.Biol.Chem., 287, 2012
4DK0
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BU of 4dk0 by Molmil
Crystal structure of MacA from Actinobacillus actinomycetemcomitans
Descriptor: Putative MacA
Authors:Xu, Y, Piao, S, Ha, N.C.
Deposit date:2012-02-03
Release date:2012-03-07
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Assembly and channel opening of outer membrane protein in tripartite drug efflux pumps of Gram-negative bacteria.
J.Biol.Chem., 287, 2012
6IOK
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BU of 6iok by Molmil
Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state)
Descriptor: Multidrug resistance protein MexA, Multidrug resistance protein MexB, Outer membrane protein OprM
Authors:Tsutsumi, K, Yonehara, R, Nakagawa, A, Yamashita, E.
Deposit date:2018-10-30
Release date:2019-04-03
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism.
Nat Commun, 10, 2019
6IOL
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BU of 6iol by Molmil
Cryo-EM structure of multidrug efflux pump MexAB-OprM (60 degree state)
Descriptor: Multidrug resistance protein MexA, Multidrug resistance protein MexB, Outer membrane protein OprM
Authors:Tsutsumi, K, Yonehara, R, Nakagawa, A, Yamashita, E.
Deposit date:2018-10-30
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism.
Nat Commun, 10, 2019

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