2QTS
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![BU of 2qts by Molmil](/molmil-images/mine/2qts) | Structure of an acid-sensing ion channel 1 at 1.9 A resolution and low pH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel, CHLORIDE ION, ... | Authors: | Jasti, J, Furukawa, H, Gonzales, E.B, Gouaux, E. | Deposit date: | 2007-08-02 | Release date: | 2007-09-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH Nature, 449, 2007
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4NTW
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![BU of 4ntw by Molmil](/molmil-images/mine/4ntw) | Structure of acid-sensing ion channel in complex with snake toxin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ... | Authors: | Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. | Deposit date: | 2013-12-02 | Release date: | 2014-02-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel. Cell(Cambridge,Mass.), 156, 2014
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4NTX
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![BU of 4ntx by Molmil](/molmil-images/mine/4ntx) | Structure of acid-sensing ion channel in complex with snake toxin and amiloride | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLOROPYRAZINECARBOXAMIDE, Acid-sensing ion channel 1, ... | Authors: | Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. | Deposit date: | 2013-12-02 | Release date: | 2014-02-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel. Cell(Cambridge,Mass.), 156, 2014
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3S3W
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![BU of 3s3w by Molmil](/molmil-images/mine/3s3w) | Structure of chicken acid-sensing ion channel 1 at 2.6 a resolution and ph 7.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive cation channel 2, ... | Authors: | Dawson, R.J.P, Benz, J, Stohler, P, Tetaz, T, Joseph, C, Huber, S, Schmid, G, Huegin, D, Pflimlin, P, Trube, G, Rudolph, M.G, Hennig, M, Ruf, A. | Deposit date: | 2011-05-18 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1. Nat Commun, 3, 2012
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4NTY
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![BU of 4nty by Molmil](/molmil-images/mine/4nty) | Cesium sites in the crystal structure of acid-sensing ion channel in complex with snake toxin | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ... | Authors: | Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. | Deposit date: | 2013-12-02 | Release date: | 2014-02-19 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel. Cell(Cambridge,Mass.), 156, 2014
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4FZ0
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![BU of 4fz0 by Molmil](/molmil-images/mine/4fz0) | |
6VTK
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![BU of 6vtk by Molmil](/molmil-images/mine/6vtk) | |
5WKU
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![BU of 5wku by Molmil](/molmil-images/mine/5wku) | Structure of an acid sensing ion channel in a resting state with barium | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ... | Authors: | Yoder, N, Gouaux, E. | Deposit date: | 2017-07-25 | Release date: | 2018-03-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Gating mechanisms of acid-sensing ion channels. Nature, 555, 2018
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3S3X
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![BU of 3s3x by Molmil](/molmil-images/mine/3s3x) | Structure of chicken acid-sensing ion channel 1 AT 3.0 A resolution in complex with psalmotoxin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive cation channel 2, neuronal, ... | Authors: | Dawson, R.J.P, Benz, J, Stohler, P, Tetaz, T, Joseph, C, Huber, S, Schmid, G, Huegin, D, Pflimlin, P, Trube, G, Rudolph, M.G, Hennig, M, Ruf, A. | Deposit date: | 2011-05-18 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1. Nat Commun, 3, 2012
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4NYK
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![BU of 4nyk by Molmil](/molmil-images/mine/4nyk) | Structure of a membrane protein | Descriptor: | Acid-sensing ion channel 1, CHLORIDE ION | Authors: | Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. | Deposit date: | 2013-12-10 | Release date: | 2014-02-12 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Pore architecture and ion sites in acid-sensing ion channels and P2X receptors. Nature, 460, 2009
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3IJ4
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![BU of 3ij4 by Molmil](/molmil-images/mine/3ij4) | |
6X9H
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![BU of 6x9h by Molmil](/molmil-images/mine/6x9h) | Molecular mechanism and structural basis of small-molecule modulation of acid-sensing ion channel 1 (ASIC1) | Descriptor: | 2-[4-(3,4-dimethoxyphenoxy)phenyl]-1H-benzimidazole-6-carboximidamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ... | Authors: | Liu, Y, Ma, J, DesJarlais, R.L, Hagan, R, Rech, J, Lin, D, Liu, C, Miller, R, Schoellerman, J, Luo, J, Letavic, M, Grasberger, B, Maher, M. | Deposit date: | 2020-06-02 | Release date: | 2020-12-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Molecular mechanism and structural basis of small-molecule modulation of the gating of acid-sensing ion channel 1. Commun Biol, 4, 2021
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5WKV
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![BU of 5wkv by Molmil](/molmil-images/mine/5wkv) | |
4FZ1
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![BU of 4fz1 by Molmil](/molmil-images/mine/4fz1) | |
6VTL
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![BU of 6vtl by Molmil](/molmil-images/mine/6vtl) | |
6CMC
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![BU of 6cmc by Molmil](/molmil-images/mine/6cmc) | |
6AVE
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![BU of 6ave by Molmil](/molmil-images/mine/6ave) | |
5WKY
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![BU of 5wky by Molmil](/molmil-images/mine/5wky) | Bromide sites in the structure of an acid sensing ion channel in a resting state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ... | Authors: | Yoder, N, Gouaux, E. | Deposit date: | 2017-07-25 | Release date: | 2018-08-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography. PLoS ONE, 13, 2018
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5WKX
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![BU of 5wkx by Molmil](/molmil-images/mine/5wkx) | Barium sites in the structure of a resting acid sensing ion channel | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ... | Authors: | Yoder, N, Gouaux, E. | Deposit date: | 2017-07-25 | Release date: | 2018-08-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4.034 Å) | Cite: | Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography. PLoS ONE, 13, 2018
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7LIE
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![BU of 7lie by Molmil](/molmil-images/mine/7lie) | |