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PDB: 9 results

1WQ6
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The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity
Descriptor: AML1-ETO
Authors:Liu, Y, Cheney, M.D, Chruszcz, M, Lukasik, S.M, Hartman, K.L, Laue, T.M, Dauter, Z, Minor, W, Speck, N.A, Bushweller, J.H.
Deposit date:2004-09-23
Release date:2005-10-04
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity
Cancer Cell, 9, 2006
4JOL
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Complex structure of AML1-ETO NHR2 domain with HEB fragment
Descriptor: Protein CBFA2T1, Transcription factor 12
Authors:Wang, Z, Patel, D.J.
Deposit date:2013-03-18
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
Nature, 500, 2013
2ODD
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Solution structure of the MYND domain from AML1-ETO complexed with SMRT, a corepressor
Descriptor: Protein CBFA2T1, SMRT, ZINC ION
Authors:Liu, Y.Z, Chen, W, Gaudet, J, Cheney, M.D, Roudaia, L, Cierpicki, T, Klet, R.C, Hartman, K, Laue, T.M, Speck, N.A, Bushweller, J.H.
Deposit date:2006-12-22
Release date:2007-06-19
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Cancer Cell, 11, 2007
2H7B
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Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO
Descriptor: Core-binding factor, ML1-ETO
Authors:Plevin, M.J, Zhang, J, Guo, C, Roeder, R.G, Ikura, M.
Deposit date:2006-06-01
Release date:2006-07-11
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain
Proc.Natl.Acad.Sci.USA, 103, 2006
2KNH
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The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide
Descriptor: Protein CBFA2T1, Transcription factor 12
Authors:Park, S, Cierpicki, T, Tonelli, M, Bushweller, J.H.
Deposit date:2009-08-25
Release date:2009-10-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.
Blood, 113, 2009
2OD1
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Solution structure of the MYND domain from human AML1-ETO
Descriptor: Protein CBFA2T1, ZINC ION
Authors:Liu, Y.Z, Chen, W, Gaudet, J, Cheney, M.D, Roudaia, L, Cierpicki, T, Klet, R.C, Hartman, K, Laue, T.M, Speck, N.A, Bushweller, J.H.
Deposit date:2006-12-21
Release date:2007-06-19
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Cancer Cell, 11, 2007
2PP4
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Solution Structure of ETO-TAFH refined in explicit solvent
Descriptor: Protein ETO
Authors:Wei, Y, Liu, S, Lausen, J, Woodrell, C, Cho, S, Biris, N, Kobayashi, N, Yokoyama, S, Werner, M.H.
Deposit date:2007-04-27
Release date:2007-06-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription
Nat.Struct.Mol.Biol., 14, 2007
2DJ8
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Solution Structure of zf-MYND Domain of Protein CBFA2TI (Protein MTG8)
Descriptor: Protein CBFA2T1, ZINC ION
Authors:Niraula, T.N, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-31
Release date:2006-10-01
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution Structure of zf-MYND Domain of Protein CBFA2TI (Protein MTG8)
To be published
2KYG
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Structure of the AML1-ETO Nervy Domain - PKA(RIIa) complex and its contribution to AML1-ETO activity
Descriptor: Protein CBFA2T1, cAMP-dependent protein kinase type II-alpha regulatory subunit
Authors:Corpora, T.A, Cierpecki, T, Bushweller, J.
Deposit date:2010-05-25
Release date:2010-10-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the AML1-ETO NHR3-PKA(RIIalpha) complex and its contribution to AML1-ETO activity.
J.Mol.Biol., 402, 2010

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