8Z7N
| |
1CID
| |
5U1F
| Initial contact of HIV-1 Env with CD4: Cryo-EM structure of BG505 DS-SOSIP trimer in complex with CD4 and antibody PGT145 | Descriptor: | BG505 DS-SOSIP gp120, BG505 SOSIP gp41, PGT145 heavy chain, ... | Authors: | Acharya, P, Kwong, P.D, Potter, C.S, Carragher, B. | Deposit date: | 2016-11-28 | Release date: | 2017-02-22 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer. Nat. Struct. Mol. Biol., 24, 2017
|
|
3T0E
| Crystal structure of a complete ternary complex of T cell receptor, peptide-MHC and CD4 | Descriptor: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ... | Authors: | Yin, Y, Mariuzza, R.A. | Deposit date: | 2011-07-20 | Release date: | 2012-03-07 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
6MET
| Structural basis of coreceptor recognition by HIV-1 envelope spike | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Shaik, M.M, Chen, B. | Deposit date: | 2018-09-07 | Release date: | 2018-12-12 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural basis of coreceptor recognition by HIV-1 envelope spike. Nature, 565, 2018
|
|
7T0O
| |
7T0R
| Crystal structure of the anti-CD4 adnectin 6940_B01 as a complex with the extracellular domains of CD4 and ibalizumab fAb | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Adnectin 6940_B01, Ibalizumab Heavy Chain, ... | Authors: | Williams, S.P, Concha, N.O, Wensel, D.L, Hong, X. | Deposit date: | 2021-11-30 | Release date: | 2022-01-12 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment. J.Mol.Biol., 434, 2021
|
|
8FYI
| Structure of HIV-1 BG505 SOSIP-HT1 in complex with one CD4 molecule | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(6-8)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fan, C, Dam, K.A, Bjorkman, P.J. | Deposit date: | 2023-01-26 | Release date: | 2023-10-18 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Intermediate conformations of CD4-bound HIV-1 Env heterotrimers. Nature, 623, 2023
|
|
8FYJ
| Structure of HIV-1 BG505 SOSIP-HT2 in complex with two CD4 molecules (class I) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Fan, C, Dam, K.A, Bjorkman, P.J. | Deposit date: | 2023-01-26 | Release date: | 2023-10-18 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Intermediate conformations of CD4-bound HIV-1 Env heterotrimers. Nature, 623, 2023
|
|
1WIP
| |
1WIO
| |
1WIQ
| |