4P7U
 
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4XJJ
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8G4K
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1M9Z
 | | CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN | | Descriptor: | GLYCEROL, TGF-BETA RECEPTOR TYPE II | | Authors: | Boesen, C.C, Radaev, S, Motyka, S.A, Patamawenu, A, Sun, P.D. | | Deposit date: | 2002-07-30 | | Release date: | 2002-09-11 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | THE 1.1A CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN
Structure, 10, 2002
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1KS6
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1PLO
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9E9G
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5TY4
 | | MicroED structure of a complex between monomeric TGF-b and its receptor, TbRII, at 2.9 A resolution | | Descriptor: | TGF-beta receptor type-2, mmTGF-b2-7m | | Authors: | Weiss, S.C, de la Cruz, M.J, Hattne, J, Shi, D, Reyes, F.E, Callero, G, Gonen, T. | | Deposit date: | 2016-11-18 | | Release date: | 2017-04-26 | | Last modified: | 2024-11-06 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.9 Å) | | Cite: | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
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9B9F
 | | Zebrafish Betaglycan Orphan Domain (zfBGo) in complex with TGF-B3 and extracellular domains of TGFBRI and TGFBRII | | Descriptor: | Transforming growth factor beta receptor type-1, Transforming growth factor beta receptor type-2, Transforming growth factor beta receptor type-3, ... | | Authors: | Wieteska, L, Taylor, A.B, Hinck, A.P. | | Deposit date: | 2024-04-02 | | Release date: | 2025-03-12 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structures of TGF-beta with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling.
Nat Commun, 16, 2025
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5TX4
 | | Derivative of mouse TGF-beta2, with a deletion of residues 52-71 and K25R, R26K, L51R, A74K, C77S, L89V, I92V, K94R T95K, I98V single amino acid substitutions, bound to human TGF-beta type II receptor ectodomain residues 15-130 | | Descriptor: | TGF-beta receptor type-2, Transforming growth factor beta-2 | | Authors: | Hinck, A.P, Kim, S. | | Deposit date: | 2016-11-15 | | Release date: | 2017-03-01 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.876 Å) | | Cite: | An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
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3KFD
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2PJY
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1KTZ
 | | Crystal Structure of the Human TGF-beta Type II Receptor Extracellular Domain in Complex with TGF-beta3 | | Descriptor: | TGF-beta Type II Receptor, TRANSFORMING GROWTH FACTOR BETA 3 | | Authors: | Hart, P.J, Deep, S, Taylor, A.B, Shu, Z, Hinck, C.S, Hinck, A.P. | | Deposit date: | 2002-01-18 | | Release date: | 2002-02-27 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex.
Nat.Struct.Biol., 9, 2002
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9FDY
 | | Betaglycan Orphan Domain (ratBGo) in complex with TGF-b1 and extracellular domain of TGFBRII | | Descriptor: | TGF-beta receptor type-2, Transforming growth factor beta receptor type 3, Transforming growth factor beta-1 | | Authors: | Wieteska, L, Cherepanov, P, Punch, E, Hinck, A.P, Hill, C.S. | | Deposit date: | 2024-05-17 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of TGF-beta with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling.
Nat Commun, 16, 2025
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9FKP
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9FK5
 | | Zebrafish Betaglycan Orphan Domain (zfBGo) in complex with TGF-B3 and extracellular domains of TGFBRI and TGFBRII | | Descriptor: | TGF-beta receptor type-1, TGF-beta receptor type-2, Transforming growth factor beta receptor III, ... | | Authors: | Wieteska, L, Coleman, J.A, Hinck, A.P. | | Deposit date: | 2024-06-02 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structures of TGF-beta with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling.
Nat Commun, 16, 2025
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