5I7M
 
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2DLA
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3Q36
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3LGB
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3L9Q
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7TL3
 | | Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF431 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER | | Authors: | Blee, A.M, Salay, L.E, Chazin, W.J. | | Deposit date: | 2022-01-18 | | Release date: | 2022-06-29 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.066 Å) | | Cite: | Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
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7TL4
 | | Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 6YF | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER | | Authors: | Blee, A.M, Salay, L.E, Chazin, W.J. | | Deposit date: | 2022-01-18 | | Release date: | 2022-06-29 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.805 Å) | | Cite: | Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
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7TL2
 | | Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF412 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, GLYCEROL, ... | | Authors: | Blee, A.M, Salay, L.E, Chazin, W.J. | | Deposit date: | 2022-01-18 | | Release date: | 2022-06-29 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.529 Å) | | Cite: | Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
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5DQO
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5F0S
 | | Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer and manganese ion | | Descriptor: | DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ... | | Authors: | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | | Deposit date: | 2015-11-28 | | Release date: | 2016-03-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.
J.Biol.Chem., 291, 2016
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5F0Q
 | | Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer | | Descriptor: | DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ... | | Authors: | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | | Deposit date: | 2015-11-28 | | Release date: | 2016-03-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.
J.Biol.Chem., 291, 2016
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6DU0
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6DI6
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6DTV
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6DTZ
 | | Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain, Y397F mutant | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, ... | | Authors: | Salay, L.E, Chazin, W.J. | | Deposit date: | 2018-06-18 | | Release date: | 2018-12-12 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6DHW
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6DI2
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7OPL
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8QJ7
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4RR2
 | | Crystal structure of human primase | | Descriptor: | DNA primase large subunit, DNA primase small subunit, IRON/SULFUR CLUSTER, ... | | Authors: | Baranovskiy, A.G, Gu, J, Suwa, Y, Babayeva, N.D, Tahirov, T.H. | | Deposit date: | 2014-11-05 | | Release date: | 2015-01-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal structure of the human primase.
J.Biol.Chem., 290, 2015
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1ZT2
 | | Heterodimeric structure of the core primase. | | Descriptor: | DNA primase large subunit, DNA primase small subunit, SULFATE ION, ... | | Authors: | Lao-Sirieix, S.H, Nookala, R.K, Roversi, P, Bell, S.D, Pellegrini, L. | | Deposit date: | 2005-05-26 | | Release date: | 2005-11-08 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.33 Å) | | Cite: | Structure of the heterodimeric core primase.
Nat.Struct.Mol.Biol., 12, 2005
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9C8V
 | | Human DNA polymerase alpha/primase - CHAPSO (4 mM) | | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | | Authors: | Abe, K.M, Li, G, He, Q, Grant, T, Lim, C. | | Deposit date: | 2024-06-13 | | Release date: | 2024-09-04 | | Last modified: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.
Nat Commun, 15, 2024
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8VY3
 | | Human DNA polymerase alpha/primase - AavLEA1 (1:40 molar ratio) | | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | | Authors: | Abe, K.M, Li, G, Grant, T, Lim, C.J. | | Deposit date: | 2024-02-06 | | Release date: | 2024-09-04 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.
Nat Commun, 15, 2024
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7UY8
 | | Tetrahymena Polymerase alpha-Primase | | Descriptor: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | | Authors: | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | | Deposit date: | 2022-05-06 | | Release date: | 2022-07-13 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
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5OFN
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