3Q36

Crystal structure of the 4Fe-4S cluster domain of human DNA primase large subunit

Summary for 3Q36

• Entry DOI: 10.2210/pdb3q36/pdb
• Related: 3L9Q 3LGB
• Descriptor: DNA primase large subunit, IRON/SULFUR CLUSTER, FE (III) ION, ... (4 entities in total)
• Functional Keywords: pol alpha, primase, dna replication, polymerase, iron-sulfur cluster, dna-binding, dna-directed rna polymerase, metal-binding, nucleotidyltransferase, phosphoprotein, primosome, transcription, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 44927.78

Authors

Agarkar, V.B.,Babayeva, N.D.,Tahirov, T.H. (deposition date: 2010-12-21, release date: 2011-04-13, Last modification date: 2023-09-13)

• Primary citation: Agarkar, V.B.,Babayeva, N.D.,Pavlov, Y.I.,Tahirov, T.H.; Crystal structure of the C-terminal domain of human DNA primase large subunit: Implications for the mechanism of the primase - polymerase alpha switch.; Cell Cycle, 10:926-931, 2011; PubMed: 21346410

Experimental method

X-RAY DIFFRACTION (2.5 Å)