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PDB: 182 results

5ILQ
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Crystal structure of truncated unliganded Aspartate Transcarbamoylase from Plasmodium falciparum
Descriptor: Aspartate carbamoyltransferase, GLYCEROL, SULFATE ION
Authors:Lunev, S, Bosch, S.S, Batista, F.D.A, Wrenger, C, Groves, M.R.
Deposit date:2016-03-04
Release date:2016-06-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum.
Acta Crystallogr.,Sect.F, 72, 2016
3AT1
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CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL PH
Descriptor: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E, Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
1EZZ
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CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE P268A MUTANT IN THE T-STATE
Descriptor: ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ZINC ION
Authors:Jin, L, Stec, B, Kantrowitz, E.R.
Deposit date:2000-05-12
Release date:2000-11-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A cis-proline to alanine mutant of E. coli aspartate transcarbamoylase: kinetic studies and three-dimensional crystal structures.
Biochemistry, 39, 2000
6OVW
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Crystal structure of ornithine carbamoyltransferase from Salmonella enterica
Descriptor: GLYCEROL, Ornithine carbamoyltransferase, PHOSPHATE ION
Authors:Chang, C, Mesa, N, Skarina, T, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-05-08
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Crystal structure of ornithine carbamoyltransferase from Salmonella enterica
To Be Published
1ZA1
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Structure of wild-type E. coli Aspartate Transcarbamoylase in the presence of CTP at 2.20 A resolution
Descriptor: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Wang, J, Stieglitz, K.A, Cardia, J.P, Kantrowitz, E.R.
Deposit date:2005-04-05
Release date:2005-06-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for ordered substrate binding and cooperativity in aspartate transcarbamoylase
Proc.Natl.Acad.Sci.Usa, 102, 2005
6PNZ
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The structure of the Aspartate Transcarbamoylase trimer from Staphylococcus aureus complexed with PALA at 2.27 Resolution.
Descriptor: Aspartate carbamoyltransferase, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
Authors:Edwards, B.F.P, Evans, D.R, Patel, C.
Deposit date:2019-07-03
Release date:2020-07-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:The structure of the Aspartate Transcarbamoylase trimer from Staphylococcus aureus complexed with PALA at 2.27 Resolution.
To Be Published
9ATC
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ATCASE Y165F MUTANT
Descriptor: ASPARTATE TRANSCARBAMOYLASE, ZINC ION
Authors:Ha, Y, Allewell, N.M.
Deposit date:1998-06-26
Release date:1999-07-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Intersubunit hydrogen bond acts as a global molecular switch in Escherichia coli aspartate transcarbamoylase.
Proteins, 33, 1998
7AT1
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CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ...
Authors:Gouaux, J.E, Stevens, R.C, Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
6FBA
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Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor 2,3-naphthalenediol
Descriptor: Aspartate transcarbamoylase, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Lunev, S, Bosch, S.S, Batista, F.A, Wang, C, Wrenger, C, Groves, M.R.
Deposit date:2017-12-18
Release date:2018-02-21
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase.
Biochem. Biophys. Res. Commun., 497, 2018
7K46
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Crystal Structure of a putative aspartate carbamoyltransferase Leishmania major Friedlin
Descriptor: 1,2-ETHANEDIOL, Aspartate carbamoyltransferase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-14
Release date:2020-09-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of a putative aspartate carbamoyltransferase Leishmania major Friedlin
to be published
7TMD
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Crystal structure of Ornithine carbamoyltransferase from Klebsiella pneumoniae
Descriptor: BROMIDE ION, IODIDE ION, Ornithine carbamoyltransferase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-01-19
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of Ornithine carbamoyltransferase from Klebsiella pneumoniae
To be published
5AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
Descriptor: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Stevens, R.C, Gouaux, J.E, Lipscomb, W.N.
Deposit date:1990-04-26
Release date:1990-10-15
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
6AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
Descriptor: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Stevens, R.C, Gouaux, J.E, Lipscomb, W.N.
Deposit date:1990-04-26
Release date:1990-10-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
7X99
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Anabolic ornithine carbamoyltransferases (OTCs) from Psychrobacter sp. PAMC 21119
Descriptor: ornithine carbamoyltransferase
Authors:Do, H, Lee, J.H.
Deposit date:2022-03-15
Release date:2022-08-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Comparative structural insight into the unidirectional catalysis of ornithine carbamoyltransferases from Psychrobacter sp. PAMC 21119.
Plos One, 17, 2022
5VMQ
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STRUCTURE OF THE R105A MUTANT CATALYTIC TRIMER OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE AT 2.0-A RESOLUTION
Descriptor: Aspartate carbamoyltransferase, CALCIUM ION, CHLORIDE ION
Authors:Beernink, P.T, Endrizzi, J.A.
Deposit date:2017-04-28
Release date:2017-05-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.012 Å)
Cite:Charge neutralization in the active site of the catalytic trimer of aspartate transcarbamoylase promotes diverse structural changes.
Protein Sci., 26, 2017
2P2G
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BU of 2p2g by Molmil
Crystal Structure of Ornithine Carbamoyltransferase from Mycobacterium Tuberculosis (Rv1656): Orthorhombic Form
Descriptor: Ornithine carbamoyltransferase, SULFATE ION
Authors:Sankaranarayanan, R, Cherney, M.M, Cherney, L.T, Garen, C, Moradian, F, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
Deposit date:2007-03-07
Release date:2007-07-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism.
J.Mol.Biol., 375, 2008
8BPL
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Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate
Descriptor: Carbamoyl-phosphate synthase (glutamine-hydrolyzing), GLYCEROL, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ...
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2022-11-16
Release date:2023-02-01
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD.
Molecules, 28, 2023
2OTC
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ORNITHINE TRANSCARBAMOYLASE COMPLEXED WITH N-(PHOSPHONACETYL)-L-ORNITHINE
Descriptor: N-(PHOSPHONOACETYL)-L-ORNITHINE, ORNITHINE CARBAMOYLTRANSFERASE
Authors:Ha, Y, Allewell, N.M.
Deposit date:1997-06-15
Release date:1998-06-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Substrate-induced conformational change in a trimeric ornithine transcarbamoylase.
Proc.Natl.Acad.Sci.USA, 94, 1997
8BPS
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BU of 8bps by Molmil
Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like in apo form
Descriptor: Carbamoyl-phosphate synthase (glutamine-hydrolyzing), GLYCEROL
Authors:del Cano-Ochoa, F, Ramon-Maiques, S.
Deposit date:2022-11-25
Release date:2023-02-01
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD.
Molecules, 28, 2023
4OH7
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Crystal structure of Ornithine carbamoyltransferase from Brucella melitensis
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Ornithine carbamoyltransferase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-01-17
Release date:2014-02-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of Ornithine carbamoyltransferase from Brucella melitensis
To be Published
8QEV
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Crystal structure of ornithine transcarbamylase from Arabidopsis thaliana (AtOTC) in complex with carbamoyl phosphate
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ornithine transcarbamylase, ...
Authors:Nielipinski, M, Pietrzyk-Brzezinska, A, Sekula, B.
Deposit date:2023-09-01
Release date:2023-12-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural analysis and molecular substrate recognition properties of Arabidopsis thaliana ornithine transcarbamylase, the molecular target of phaseolotoxin produced by Pseudomonas syringae .
Front Plant Sci, 14, 2023
3GRF
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X-ray Structure of Ornithine Transcarbamoylase from Giardia lamblia
Descriptor: NICKEL (II) ION, Ornithine carbamoyltransferase
Authors:Galkin, A, Herzberg, O.
Deposit date:2009-03-25
Release date:2009-06-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure and kinetic properties of ornithine transcarbamoylase from the human parasite Giardia lamblia.
Proteins, 76, 2009
8QEU
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Crystal structure of ornithine transcarbamylase from Arabidopsis thaliana (AtOTC) in complex with ornithine
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, L-ornithine, ...
Authors:Nielipinski, M, Pietrzyk-Brzezinska, A, Sekula, B.
Deposit date:2023-09-01
Release date:2023-12-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural analysis and molecular substrate recognition properties of Arabidopsis thaliana ornithine transcarbamylase, the molecular target of phaseolotoxin produced by Pseudomonas syringae .
Front Plant Sci, 14, 2023
4NF2
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Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline
Descriptor: CHLORIDE ION, NORVALINE, Ornithine carbamoyltransferase, ...
Authors:Shabalin, I.G, Handing, K, Cymborowski, M.T, Stam, J, Winsor, J, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-10-30
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis
To be Published
1JS1
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Crystal Structure of a new transcarbamylase from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution
Descriptor: PHOSPHATE ION, Transcarbamylase
Authors:Shi, D, Gallegos, R, DePonte III, J, Morizono, H, Yu, X, Allewell, N.M, Malamy, M, Tuchman, M.
Deposit date:2001-08-15
Release date:2002-07-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a transcarbamylase-like protein from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution.
J.Mol.Biol., 320, 2002

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