7T9R
 
 | | Crystal structure of Crocodile defensin CpoBD13:phosphatidic acid complex | | Descriptor: | (R)-2-(FORMYLOXY)-3-(PHOSPHONOOXY)PROPYL PENTANOATE, 1,2-ETHANEDIOL, CpoBD13, ... | | Authors: | Kvansakul, M, Williams, S, Hulett, M.D. | | Deposit date: | 2021-12-19 | | Release date: | 2023-01-18 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption.
Nat Commun, 14, 2023
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1UT3
 | | Solution Structure of Spheniscin-2, a beta-Defensin from Penguin Stomach Preserving Food | | Descriptor: | SPHENISCIN-2 | | Authors: | Landon, C, Labbe, H, Thouzeau, C, Bulet, P, Vovelle, F. | | Deposit date: | 2003-12-02 | | Release date: | 2004-05-06 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Spheniscin, a {Beta}-Defensin from the Penguin Stomach
J.Biol.Chem., 279, 2004
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2PLZ
 | | Arg-modified human beta-defensin 1 (HBD1) | | Descriptor: | Beta-defensin 1, SULFATE ION | | Authors: | Lubkowski, J, Pazgier, M, Lu, W. | | Deposit date: | 2007-04-20 | | Release date: | 2007-05-29 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs.
J.Biol.Chem., 282, 2007
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6M56
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6CS9
 | | Crystal structure of human beta-defensin 2 in complex with PIP2 | | Descriptor: | Beta-defensin 4A, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | Authors: | Jarva, M, Phan, K, Lay, F.T, Humble, C, Hulett, M, Kvansakul, M. | | Deposit date: | 2018-03-20 | | Release date: | 2018-07-25 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Human beta-defensin 2 killsCandida albicansthrough phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization.
Sci Adv, 4, 2018
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7LZL
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7T9Q
 | | Crystal structure of Crocodile defensin CpoBD13 | | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, CpoBD13 | | Authors: | Kvansakul, M, Williams, S, Hulett, M.D. | | Deposit date: | 2021-12-19 | | Release date: | 2023-01-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption.
Nat Commun, 14, 2023
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5LCS
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8YD6
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1BNB
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1IJU
 | | HUMAN BETA-DEFENSIN-1 | | Descriptor: | BETA-DEFENSIN 1, GLYCEROL, SULFATE ION | | Authors: | Hoover, D.M, Lubkowski, J. | | Deposit date: | 2001-04-30 | | Release date: | 2001-10-24 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The structure of human beta-defensin-1: new insights into structural properties of beta-defensins.
J.Biol.Chem., 276, 2001
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1IJV
 | | HUMAN BETA-DEFENSIN-1 | | Descriptor: | BROMIDE ION, Beta-defensin 1, POTASSIUM ION, ... | | Authors: | Hoover, D.M, Lubkowski, J. | | Deposit date: | 2001-04-30 | | Release date: | 2001-10-24 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The structure of human beta-defensin-1: new insights into structural properties of beta-defensins.
J.Biol.Chem., 276, 2001
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1KJ6
 | | Solution Structure of Human beta-Defensin 3 | | Descriptor: | Beta-defensin 3 | | Authors: | Schibli, D.J, Hunter, H.N, Aseyev, V, Starner, T.D, Wiencek, J.M, McCray Jr, P.B, Tack, B.F, Vogel, H.J. | | Deposit date: | 2001-12-04 | | Release date: | 2002-03-20 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus.
J.Biol.Chem., 277, 2002
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1KJ5
 | | Solution Structure of Human beta-defensin 1 | | Descriptor: | BETA-DEFENSIN 1 | | Authors: | Schibli, D.J, Hunter, H.N, Aseyev, V, Starner, T.D, Wiencek, J.M, McCray Jr, P.B, Tack, B.F, Vogel, H.J. | | Deposit date: | 2001-12-04 | | Release date: | 2002-03-20 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus.
J.Biol.Chem., 277, 2002
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1E4T
 | | Solution structure of the mouse defensin mBD-7 | | Descriptor: | Beta-defensin 7 | | Authors: | Bauer, F, Schweimer, K, Kluver, E, Adermann, K, Forssmann, W.G, Roesch, P, Sticht, H. | | Deposit date: | 2000-07-12 | | Release date: | 2001-07-12 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity.
Protein Sci., 10, 2001
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1E4Q
 | | Solution structure of the human defensin hBD-2 | | Descriptor: | BETA-DEFENSIN 2 | | Authors: | Bauer, F, Schweimer, K, Kluver, E, Adermann, K, Forssmann, W.G, Roesch, P, Sticht, H. | | Deposit date: | 2000-07-12 | | Release date: | 2001-07-12 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Structure Determination of Human and Murine Beta-Defensins Reveals Structural Conservation in the Absence of Significant Sequence Similarity
Protein Sci., 10, 2001
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1E4S
 | | Solution structure of the human defensin hBD-1 | | Descriptor: | BETA-DEFENSIN 1 | | Authors: | Bauer, F, Schweimer, K, Kluver, E, Adermann, K, Forssmann, W.G, Roesch, P, Sticht, H. | | Deposit date: | 2000-07-12 | | Release date: | 2001-07-12 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Structure Determination of Human and Murine Beta-Defensins Reveals Structural Conservation in the Absence of Significant Sequence Similarity
Protein Sci., 10, 2001
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1E4R
 | | Solution structure of the mouse defensin mBD-8 | | Descriptor: | Beta-defensin 8 | | Authors: | Bauer, F, Schweimer, K, Kluver, E, Adermann, K, Forssmann, W.G, Roesch, P, Sticht, H. | | Deposit date: | 2000-07-12 | | Release date: | 2001-07-12 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity.
Protein Sci., 10, 2001
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1FQQ
 | | SOLUTION STRUCTURE OF HUMAN BETA-DEFENSIN-2 | | Descriptor: | BETA-DEFENSIN-2 | | Authors: | Sawai, M.V, Jia, H.P, Liu, L, Aseyev, V, Wiencek, J.M, McCray Jr, P.B, Ganz, T, Kearney, W.R, Tack, B.F. | | Deposit date: | 2000-09-06 | | Release date: | 2001-04-11 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | The NMR structure of human beta-defensin-2 reveals a novel alpha-helical segment.
Biochemistry, 40, 2001
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1FD3
 | | HUMAN BETA-DEFENSIN 2 | | Descriptor: | BETA-DEFENSIN 2, SULFATE ION | | Authors: | Hoover, D.M, Lubkowski, J. | | Deposit date: | 2000-07-19 | | Release date: | 2000-11-01 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | The structure of human beta-defensin-2 shows evidence of higher order oligomerization.
J.Biol.Chem., 275, 2000
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1FD4
 | | HUMAN BETA-DEFENSIN 2 | | Descriptor: | BETA-DEFENSIN 2, SULFATE ION | | Authors: | Hoover, D.M, Lubkowski, J. | | Deposit date: | 2000-07-19 | | Release date: | 2000-11-01 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The structure of human beta-defensin-2 shows evidence of higher order oligomerization.
J.Biol.Chem., 275, 2000
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2LG6
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2NLF
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2NLE
 | | Human beta-defensin-1 (Mutant Gln11Ala) | | Descriptor: | ACETATE ION, Beta-defensin 1, SULFATE ION | | Authors: | Lubkowski, J, Pazgier, M. | | Deposit date: | 2006-10-20 | | Release date: | 2006-10-31 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007
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2NLC
 | | Human beta-defensin-1 (mutant Ser8Ala) | | Descriptor: | ACETATE ION, Beta-defensin 1, SULFATE ION | | Authors: | Lubkowski, J, Pazgier, M. | | Deposit date: | 2006-10-20 | | Release date: | 2006-10-31 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007
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