7T9R

Crystal structure of Crocodile defensin CpoBD13:phosphatidic acid complex

Summary for 7T9R

• Entry DOI: 10.2210/pdb7t9r/pdb
• Related: 7T9Q
• Descriptor: CpoBD13, 1,2-ETHANEDIOL, (R)-2-(FORMYLOXY)-3-(PHOSPHONOOXY)PROPYL PENTANOATE, ... (5 entities in total)
• Functional Keywords: defensin, phosphatidic acid, complex, phospholipid, antimicrobial protein
• Biological source: Crocodylus porosus
• Total number of polymer chains: 4
• Total formula weight: 20030.44

Authors

Kvansakul, M.,Williams, S.,Hulett, M.D. (deposition date: 2021-12-19, release date: 2023-01-18, Last modification date: 2023-10-25)

• Primary citation: Williams, S.A.,Lay, F.T.,Bindra, G.K.,Banjara, S.,Poon, I.K.H.,Phan, T.K.,Kvansakul, M.,Hulett, M.D.; Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption.; Nat Commun, 14:1170-1170, 2023; PubMed: 36859344; DOI: 10.1038/s41467-023-36280-y

Experimental method

X-RAY DIFFRACTION (1.45 Å)