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PDB: 471 results

3S6M
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BU of 3s6m by Molmil
The structure of a Peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Peptidyl-prolyl cis-trans isomerase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-05-25
Release date:2011-06-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:The structure of a Peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei
TO BE PUBLISHED
2OSE
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BU of 2ose by Molmil
Crystal Structure of the Mimivirus Cyclophilin
Descriptor: CHLORIDE ION, Probable peptidyl-prolyl cis-trans isomerase
Authors:Eisenmesser, E.Z, Thai, V, Renesto, P, Raoult, D.
Deposit date:2007-02-05
Release date:2007-12-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural, biochemical, and in vivo characterization of the first virally encoded cyclophilin from the Mimivirus.
J.Mol.Biol., 378, 2008
4DGC
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BU of 4dgc by Molmil
TRIMCyp cyclophilin domain from Macaca mulatta: cyclosporin A complex
Descriptor: TRIMCyp, cyclosporin A
Authors:Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C.
Deposit date:2012-01-25
Release date:2012-02-08
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
4XNC
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BU of 4xnc by Molmil
Crystal structure at room temperature of cyclophilin D in complex with an inhibitor
Descriptor: Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ethyl N-[(4-aminobenzyl)carbamoyl]glycinate
Authors:Gelin, M, Allemand, F, Labesse, G, Guichou, J.F.
Deposit date:2015-01-15
Release date:2015-08-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography.
Acta Crystallogr.,Sect.D, 71, 2015
8EJX
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BU of 8ejx by Molmil
Crystal structure of human cyclophilin D (CypD) with in complex with the covalently bound Ebselen inhibitor
Descriptor: N-phenyl-2-selanylbenzamide, Peptidyl-prolyl cis-trans isomerase F, mitochondrial
Authors:Lovell, S, Battaile, K.P, Yan, S.
Deposit date:2022-09-19
Release date:2023-10-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer's disease.
Brain, 147, 2024
6BTA
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BU of 6bta by Molmil
CypA Mutant - S99T C115S
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Fraser, J.S, Kenner, L.R, Liu, L.
Deposit date:2017-12-06
Release date:2018-04-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Rescue of conformational dynamics in enzyme catalysis by directed evolution.
Nat Commun, 9, 2018
5WC7
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BU of 5wc7 by Molmil
CypA Mutant - I97V S99T C115S
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Fraser, J.S.
Deposit date:2017-06-29
Release date:2018-04-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Rescue of conformational dynamics in enzyme catalysis by directed evolution.
Nat Commun, 9, 2018
4CYH
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BU of 4cyh by Molmil
CYCLOPHILIN A COMPLEXED WITH DIPEPTIDE HIS-PRO
Descriptor: CYCLOPHILIN A, HISTIDINE, PROLINE
Authors:Zhao, Y, Ke, H.
Deposit date:1996-02-27
Release date:1996-07-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanistic implication of crystal structures of the cyclophilin-dipeptide complexes.
Biochemistry, 35, 1996
7L6Y
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BU of 7l6y by Molmil
Crystal Structure of the Peptidyl-Prolyl Cis-Trans Isomerase (PpiB) from Streptococcus pyogenes.
Descriptor: Peptidyl-prolyl cis-trans isomerase
Authors:Minasov, G, Shuvalova, L, Kiryukhina, O, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-12-24
Release date:2021-12-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Crystal Structure of the Peptidyl-Prolyl Cis-Trans Isomerase (PpiB) from Streptococcus pyogenes.
To Be Published
7L6Z
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Crystal Structure of Peptidyl-Prolyl Cis-Trans Isomerasefrom (PpiB) Streptococcus pneumoniae R6
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-12-24
Release date:2021-12-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal Structure of Peptidyl-Prolyl Cis-Trans Isomerasefrom (PpiB) Streptococcus pneumoniae R6
To Be Published
1Z81
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BU of 1z81 by Molmil
Crystal Structure of cyclophilin from Plasmodium yoelii.
Descriptor: cyclophilin
Authors:Mulichak, A, Alam, Z, Amani, M, Lew, J, Wasney, G, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Hui, R, Vedadi, M, Structural Genomics Consortium (SGC)
Deposit date:2005-03-29
Release date:2005-04-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
7RFD
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BU of 7rfd by Molmil
E. coli peptidyl-prolyl cis-trans isomerase, mutant Phe4Ala Phe27CF3-Phe/Phe98CF3-Phe
Descriptor: Peptidyl-prolyl cis-trans isomerase
Authors:Frkic, R.L, Otting, G, Jackson, C.J.
Deposit date:2021-07-14
Release date:2021-09-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Through-Space Scalar 19 F- 19 F Couplings between Fluorinated Noncanonical Amino Acids for the Detection of Specific Contacts in Proteins.
J.Am.Chem.Soc., 143, 2021
1ZKF
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BU of 1zkf by Molmil
Cyrstal Structure of Human Cyclophilin-A in Complex with suc-AGPF-pNA
Descriptor: Peptidyl-prolyl cis-trans isomerase A, Suc-ALA-GLY-PRO-PHE-pNA
Authors:Eisenmesser, E.Z, Thai, V, Pozharski, E, Kern, D.
Deposit date:2005-05-02
Release date:2006-04-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Mechanistic Insights of Cyclophilin-A from X-Ray Cyrstallographic and Nuclear Magnet Resonance Investigations
To be Published
7N3J
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BU of 7n3j by Molmil
E. coli peptidyl-prolyl cis-trans isomerase, mutant Phe27CF3-Tyr/Phe98CF3-Tyr
Descriptor: Peptidyl-prolyl cis-trans isomerase B
Authors:Frkic, R.L, Otting, G, Jackson, C.J.
Deposit date:2021-06-01
Release date:2021-09-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Through-Space Scalar 19 F- 19 F Couplings between Fluorinated Noncanonical Amino Acids for the Detection of Specific Contacts in Proteins.
J.Am.Chem.Soc., 143, 2021
7ZFM
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BU of 7zfm by Molmil
Engineered Protein Targeting the Zika Viral Envelope Fusion Loop
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, HEXAETHYLENE GLYCOL, ...
Authors:Athayde, D, Archer, M, Viana, I.F.T, Adan, W.C.S, Xavier, L.S.S, Lins, R.D.
Deposit date:2022-04-01
Release date:2022-08-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.711 Å)
Cite:In Vitro Neutralisation of Zika Virus by an Engineered Protein Targeting the Viral Envelope Fusion Loop
SSRN, 2022
7ZDN
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BU of 7zdn by Molmil
Human Cyclophilin D in complex with fragment
Descriptor: (1~{R},9~{R},10~{S})-12-oxa-8-azatricyclo[7.3.1.0^{2,7}]trideca-2(7),3,5-trien-10-ol, Peptidyl-prolyl cis-trans isomerase F, mitochondrial
Authors:Silva, D.O, Graedler, U, Bandeiras, T.M.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Human Cyclophilin D in complex with fragment
To Be Published
3T1U
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BU of 3t1u by Molmil
Crystal Structure of the complex of Cyclophilin-A enzyme from Azotobacter vinelandii with sucAFPFpNA peptide
Descriptor: Peptidyl-prolyl cis-trans isomerase, succinyl-Ala-Phe-Pro-Phe-p-nitroanilide
Authors:Karpusas, M, Christoforides, E, Bethanis, K, Dimou, M, Katinakis, P.
Deposit date:2011-07-22
Release date:2012-03-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a bacterial cytoplasmic cyclophilin A in complex with a tetrapeptide.
Acta Crystallogr.,Sect.F, 68, 2012
3UCH
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BU of 3uch by Molmil
Crystal structure of a peptidyl-prolyl cis-trans isomerase E (PPIE) from Homo sapiens at 2.50 A resolution
Descriptor: Peptidyl-prolyl cis-trans isomerase E
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2011-10-26
Release date:2011-11-16
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a Hypotherical Peptidyl-prolyl cis-trans isomerase E (PPIE) from Homo sapiens at 2.50 A resolution
To be published
5HSV
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BU of 5hsv by Molmil
X-Ray structure of a CypA-Alisporivir complex at 1.5 angstrom resolution
Descriptor: Alisporivir, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase A
Authors:Dujardin, M, Bouckaert, J, Rucktooa, P, Hanoulle, X.
Deposit date:2016-01-26
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:X-ray structure of alisporivir in complex with cyclophilin A at 1.5 angstrom resolution.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6U5C
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BU of 6u5c by Molmil
RT XFEL structure of CypA solved using MESH injection system
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Wolff, A.M, Thompson, M.C.
Deposit date:2019-08-27
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals
Iucrj, 7, 2020
6U5E
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BU of 6u5e by Molmil
RT XFEL structure of CypA solved using celloluse carrier media
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Wolff, A.M, Nango, E, Nakane, T, Young, I.D, Brewster, A.S, Sugahara, M, Tanaka, R, Sauter, N.K, Tono, K, Iwata, S, Fraser, J.S, Thompson, M.C.
Deposit date:2019-08-27
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals
Iucrj, 7, 2020
6U5G
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BU of 6u5g by Molmil
MicroED structure of a FIB-milled CypA Crystal
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Wolff, A.M, Martynowycz, M.W, Zhao, W, Gonen, T, Fraser, J.S, Thompson, M.C.
Deposit date:2019-08-27
Release date:2020-01-29
Last modified:2023-10-11
Method:ELECTRON CRYSTALLOGRAPHY (2.5 Å)
Cite:Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals
Iucrj, 7, 2020
6LXP
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TvCyP2 in apo form 2
Descriptor: Peptidyl-prolyl cis-trans isomerase
Authors:Aryal, S, Chen, C, Hsu, C.H.
Deposit date:2020-02-11
Release date:2020-09-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:N-Terminal Segment of TvCyP2 Cyclophilin fromTrichomonas vaginalisIs Involved in Self-Association, Membrane Interaction, and Subcellular Localization.
Biomolecules, 10, 2020
8B58
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BU of 8b58 by Molmil
Crystal Structure of Cyclophilin TgCyp23 from Toxoplasma gondii in complex with Cyclosporin A
Descriptor: Cyclosporin A, Peptidyl-prolyl cis-trans isomerase
Authors:Jimenez-Faraco, E, Hermoso, J.A.
Deposit date:2022-09-22
Release date:2023-02-01
Last modified:2023-02-22
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural Basis for Cyclosporin Isoform-Specific Inhibition of Cyclophilins from Toxoplasma gondii .
Acs Infect Dis., 9, 2023
6LXO
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BU of 6lxo by Molmil
TvCyP2 in apo form 1
Descriptor: GLYCEROL, Peptidyl-prolyl cis-trans isomerase, SULFATE ION
Authors:Aryal, S, Chen, C, Hsu, C.H.
Deposit date:2020-02-11
Release date:2020-09-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:N-Terminal Segment of TvCyP2 Cyclophilin fromTrichomonas vaginalisIs Involved in Self-Association, Membrane Interaction, and Subcellular Localization.
Biomolecules, 10, 2020

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