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PDB: 544 results

4ZNX
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BU of 4znx by Molmil
Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12
Descriptor: APP12, Tyrosine-protein kinase Fyn
Authors:Camara-Artigas, A.
Deposit date:2015-05-05
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.
Acta Crystallogr.,Sect.F, 72, 2016
9OFX
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BU of 9ofx by Molmil
Crystal structure of c-Src SH3 domain in H32 space group mediated by nickel
Descriptor: GLYCEROL, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
Authors:Stiegler, A.L, Calicdan, X, Ha, B.H, Fisher, O.S, Boggon, T.J.
Deposit date:2025-04-30
Release date:2025-05-14
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of c-Src SH3 domain in H32 space group mediated by nickel
To Be Published
5XG9
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BU of 5xg9 by Molmil
Crystal Structure of PEG-bound SH3 domain of Myosin IB from Entamoeba histolytica
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, PENTAETHYLENE GLYCOL, ...
Authors:Gautam, G, Gourinath, S.
Deposit date:2017-04-13
Release date:2017-08-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition
Acta Crystallogr D Struct Biol, 73, 2017
9HDB
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BU of 9hdb by Molmil
Sla1 SH3_3 domain (residues 355-414)
Descriptor: Actin cytoskeleton-regulatory complex protein SLA1
Authors:Draper-Barr, G, Defelipe, L.A, Ruiz-Carillo, D, Garcia-Alai, M.M.
Deposit date:2024-11-12
Release date:2025-05-21
Method:X-RAY DIFFRACTION (1.491 Å)
Cite:Sla2 is a core interaction hub for clathrin light chain and the Pan1/End3/Sla1 complex.
Structure, 2025
7JT9
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BU of 7jt9 by Molmil
Fgr SH3 domain crystal structure
Descriptor: Tyrosine-protein kinase Fgr
Authors:Perez, I, Berndt, S, Gurevich, V.V, Iverson, T.M.
Deposit date:2020-08-17
Release date:2022-01-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr.
J.Mol.Biol., 434, 2022
5L23
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BU of 5l23 by Molmil
Crystal structure of the complex between the N-terminal SH3 domain of CrkII and a proline-rich ligand
Descriptor: Adapter molecule crk, C3G derived peptide, DI(HYDROXYETHYL)ETHER
Authors:Bhatt, V.S, Krieger, I, Sacchettini, J, Cho, J.-H.
Deposit date:2016-07-30
Release date:2016-09-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of the complex between the N-terminal SH3 domain of CrkII and a proline-rich ligand
To Be Published
6NMW
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BU of 6nmw by Molmil
Crystal structure of the human Lyn SH3 domain
Descriptor: Tyrosine-protein kinase Lyn
Authors:Berndt, S, Gurevich, V.V, Iverson, T.M.
Deposit date:2019-01-12
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:Crystal structure of the SH3 domain of human Lyn non-receptor tyrosine kinase.
PLoS ONE, 14, 2019
2K2M
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BU of 2k2m by Molmil
Structural Basis of PxxDY Motif Recognition in SH3 Binding
Descriptor: Eps8-like protein 1
Authors:Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Saksela, K, Permi, P.
Deposit date:2008-04-02
Release date:2009-02-17
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structural basis of PxxDY motif recognition in SH3 binding.
J.Mol.Biol., 382, 2008
6IPY
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BU of 6ipy by Molmil
His-tagged Fyn SH3 domain R96I mutant
Descriptor: Tyrosine-protein kinase Fyn
Authors:Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.343 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
6IPZ
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BU of 6ipz by Molmil
Fyn SH3 domain R96W mutant, crystallized with 18-crown-6
Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Tyrosine-protein kinase Fyn
Authors:Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
6C4S
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BU of 6c4s by Molmil
Human cSrc SH3 Domain in complex with Choline Kinase fragment 60-69
Descriptor: Proto-oncogene tyrosine-protein kinase Src,cSrc SH3 Domain, ZINC ION
Authors:Kall, S.L, Lavie, A.
Deposit date:2018-01-12
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase.
Sci Rep, 9, 2019
4Y92
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BU of 4y92 by Molmil
Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant
Descriptor: GLYCEROL, Protein-tyrosine kinase, SULFATE ION, ...
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2015-02-16
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant
to be published
6EDF
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BU of 6edf by Molmil
Fragment of a tyrosine-protein kinase
Descriptor: FYN, GLYCEROL, UNKNOWN ATOM OR ION
Authors:Tempel, W, Huang, H, Sochirca, I, Liu, K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Sidhu, S.S, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-08-09
Release date:2018-08-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Fragment of a tyrosine-protein kinase
To be Published
1HSQ
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BU of 1hsq by Molmil
SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA
Descriptor: PHOSPHOLIPASE C-GAMMA (SH3 DOMAIN)
Authors:Kohda, D, Hatanaka, H, Odaka, M, Inagaki, F.
Deposit date:1994-06-13
Release date:1994-08-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain of phospholipase C-gamma.
Cell(Cambridge,Mass.), 72, 1993
6SCW
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BU of 6scw by Molmil
SH3-subunit of chicken alpha spectrin solved by NMR
Descriptor: Spectrin alpha chain, non-erythrocytic 1 isoform X11
Authors:Grohe, K, Hebrank, C, Linser, R.
Deposit date:2019-07-25
Release date:2020-08-12
Last modified:2024-01-31
Method:SOLUTION NMR
Cite:Protein Motional Details Revealed by Complementary Structural Biology Techniques.
Structure, 28, 2020
1I07
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BU of 1i07 by Molmil
EPS8 SH3 DOMAIN INTERTWINED DIMER
Descriptor: EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8
Authors:Kishan, K.V.R, Newcomer, M.E.
Deposit date:2001-01-29
Release date:2001-05-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
1I0C
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BU of 1i0c by Molmil
EPS8 SH3 CLOSED MONOMER
Descriptor: EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8
Authors:Kishan, K.V.R, Newcomer, M.E.
Deposit date:2001-01-29
Release date:2001-05-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
6SDF
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BU of 6sdf by Molmil
N-terminal SH3 domain of Grb2 protein
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Growth factor receptor-bound protein 2
Authors:Bolgov, A.A, Korban, S.A, Luzik, D.A, Rogacheva, O.N, Zhemkov, V.A, Kim, M, Skrynnikov, N.R, Bezprozvanny, I.B.
Deposit date:2019-07-26
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the SH3 domain of growth factor receptor-bound protein 2.
Acta Crystallogr.,Sect.F, 76, 2020
5UL6
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BU of 5ul6 by Molmil
The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions
Descriptor: Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus
Authors:Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H.
Deposit date:2017-01-24
Release date:2017-08-09
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus.
ACS Chem. Biol., 12, 2017
5VEI
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BU of 5vei by Molmil
Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
Descriptor: Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION
Authors:Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2017-04-04
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
To be Published
8CHH
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BU of 8chh by Molmil
SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the correction method for spin-diffusion with PDB 2NUZ as reference
Descriptor: Spectrin alpha chain, non-erythrocytic 1
Authors:Soeldner, B.
Deposit date:2023-02-08
Release date:2023-03-08
Last modified:2024-06-19
Method:SOLID-STATE NMR
Cite:Integrated Assessment of the Structure and Dynamics of Solid Proteins.
J Phys Chem Lett, 14, 2023
8CF4
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BU of 8cf4 by Molmil
SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the combined correction method with PDB 2NUZ
Descriptor: Spectrin alpha chain, non-erythrocytic 1
Authors:Soeldner, B.
Deposit date:2023-02-02
Release date:2023-03-08
Last modified:2024-06-19
Method:SOLID-STATE NMR
Cite:Integrated Assessment of the Structure and Dynamics of Solid Proteins.
J Phys Chem Lett, 14, 2023
8CHG
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BU of 8chg by Molmil
SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the correction for dipolar truncation with PDB 2NUZ
Descriptor: Spectrin alpha chain, non-erythrocytic 1
Authors:Soeldner, B.
Deposit date:2023-02-08
Release date:2023-03-08
Last modified:2024-06-19
Method:SOLID-STATE NMR
Cite:Integrated Assessment of the Structure and Dynamics of Solid Proteins.
J Phys Chem Lett, 14, 2023
6RO9
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BU of 6ro9 by Molmil
Human spectrin SH3 domain D48G, E7V, K60V
Descriptor: Spectrin alpha, non-erythrocytic 1
Authors:Reverter, D, Navarro, S, Ventura, S.
Deposit date:2019-05-10
Release date:2020-06-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.814 Å)
Cite:Human spectrin SH3 domain D48G, E7V, K60V
To Be Published
6XVM
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BU of 6xvm by Molmil
Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 2
Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Plaza-Garrido, M.
Deposit date:2020-01-22
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020

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PDB entries from 2025-06-11

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