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PDB: 61 results
3SD6
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BU of 3sd6 by Molmil
Crystal structure of the amino-terminal domain of human cardiac troponin C in complex with cadmium at 1.4 resolution.
Descriptor: ACETATE ION, CADMIUM ION, CALCIUM ION, ...
Authors:Zhang, X.L, Paetzel, M.
Deposit date:2011-06-08
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:The structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination.
Acta Crystallogr.,Sect.D, 69, 2013
4GJE
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BU of 4gje by Molmil
Crystal structure of the refolded amino-terminal domain of human cardiac troponin C in complex with cadmium
Descriptor: ACETATE ION, CADMIUM ION, CALCIUM ION, ...
Authors:Zhang, X, Paetzel, M.
Deposit date:2012-08-09
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination.
Acta Crystallogr.,Sect.D, 69, 2013
3SWB
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BU of 3swb by Molmil
Crystal structure of the amino-terminal domain of human cardiac troponin C in complex with cadmium at 1.7 A resolution
Descriptor: ACETATE ION, CADMIUM ION, CALCIUM ION, ...
Authors:Zhang, X.L, Paetzel, M.
Deposit date:2011-07-13
Release date:2012-07-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:The structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination.
Acta Crystallogr.,Sect.D, 69, 2013
7SC2
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BU of 7sc2 by Molmil
CRYSTAL STRUCTURE OF THE N-DOMAIN OF CARDIAC MUSCLE TROPONIN C TETHERED TO THE SWITCH REGION OF CARDIAC MUSCLE TROPONIN I (TETRAGONAL FORM)
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles,Troponin I, ...
Authors:Sack, J.S.
Deposit date:2021-09-27
Release date:2021-12-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.814 Å)
Cite:X-ray structure of a human cardiac muscle troponin C/troponin I chimera in two crystal forms.
Acta Crystallogr.,Sect.F, 78, 2022
4GJF
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BU of 4gjf by Molmil
Crystal structure of the amino-terminal domain of human cardiac troponin C mutant L29Q in complex with cadmium
Descriptor: ACETATE ION, CADMIUM ION, CALCIUM ION, ...
Authors:Zhang, X, Paetzel, M.
Deposit date:2012-08-09
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination.
Acta Crystallogr.,Sect.D, 69, 2013
4GJG
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BU of 4gjg by Molmil
Crystal structure of the amino-terminal domain of human cardiac troponin C mutant D2N/V28I/L29Q/G30D (NIQD) in complex with cadmium.
Descriptor: ACETATE ION, CADMIUM ION, CALCIUM ION, ...
Authors:Zhang, X, Paetzel, M.
Deposit date:2012-08-09
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of cardiac troponin C regulatory domain with bound Cd(2+) reveals a closed conformation and unique ion coordination.
Acta Crystallogr.,Sect.D, 69, 2013
4Y99
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BU of 4y99 by Molmil
Core domain of human cardiac troponin
Descriptor: CALCIUM ION, DIMETHYL SULFOXIDE, Troponin C, ...
Authors:Takeda, S.
Deposit date:2015-02-17
Release date:2016-03-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Core domain of human cardiac troponin
To Be Published
1WRK
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BU of 1wrk by Molmil
Crystal structure of the N-terminal domain of human cardiac troponin C in complex with trifluoperazine (orthrombic crystal form)
Descriptor: 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE, CALCIUM ION, Troponin C, ...
Authors:Takeda, S, Igarashi, T, Oishi, Y, Mori, H.
Deposit date:2004-10-20
Release date:2006-01-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the N-terminal domain of human cardiac troponin C in complex with trifluoperazine
To be Published
3RV5
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BU of 3rv5 by Molmil
Crystal structure of human cardiac troponin C regulatory domain in complex with cadmium and deoxycholic acid
Descriptor: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, CADMIUM ION, CALCIUM ION, ...
Authors:Li, A.Y, Lee, J, Borek, D, Otwinowski, Z, Tibbits, G, Paetzel, M.
Deposit date:2011-05-06
Release date:2011-08-31
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of cardiac troponin C regulatory domain in complex with cadmium and deoxycholic Acid reveals novel conformation.
J.Mol.Biol., 413, 2011
7SC3
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BU of 7sc3 by Molmil
CRYSTAL STRUCTURE OF THE N-DOMAIN OF CARDIAC MUSCLE TROPONIN C TETHERED TO THE SWITCH REGION OF CARDIAC MUSCLE TROPONIN I (ORTHORHOMBIC FORM)
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles,Troponin I, ...
Authors:Sack, J.S.
Deposit date:2021-09-27
Release date:2021-12-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.229 Å)
Cite:X-ray structure of a human cardiac muscle troponin C/troponin I chimera in two crystal forms.
Acta Crystallogr.,Sect.F, 78, 2022
1WRL
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BU of 1wrl by Molmil
Crystal structure of the N-terminal domain of human cardiac troponin C in complex with trifluoperazine (monoclinic crystal form)
Descriptor: 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE, CALCIUM ION, Troponin C, ...
Authors:Takeda, S, Igarashi, T, Oishi, Y, Mori, H.
Deposit date:2004-10-20
Release date:2006-01-24
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the N-terminal domain of human cardiac troponin C in complex with trifluoperazine
To be Published
1J1D
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BU of 1j1d by Molmil
Crystal structure of the 46kDa domain of human cardiac troponin in the Ca2+ saturated form
Descriptor: CALCIUM ION, Troponin C, Troponin I, ...
Authors:Takeda, S, Yamashita, A, Maeda, K, Maeda, Y.
Deposit date:2002-12-03
Release date:2003-07-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
Nature, 424, 2003
8FMO
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BU of 8fmo by Molmil
Complex structure of K210 deletion Troponin complex with risedronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (2.612 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMT
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BU of 8fmt by Molmil
Complex structure of TnnT-R205L Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMN
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BU of 8fmn by Molmil
Complex structure of K210 deletion Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-23
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMM
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BU of 8fmm by Molmil
Complex structure of wild type Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-23
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.112 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMR
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BU of 8fmr by Molmil
Complex structure of K210 deletion Troponin complex with ibandronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.238 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMP
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BU of 8fmp by Molmil
Complex structure of K210 deletion Troponin complex with pamidronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMQ
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BU of 8fmq by Molmil
Complex structure of K210 deletion Troponin complex with alendronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.248 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
1J1E
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BU of 1j1e by Molmil
Crystal structure of the 52kDa domain of human cardiac troponin in the Ca2+ saturated form
Descriptor: CALCIUM ION, Troponin C, Troponin I, ...
Authors:Takeda, S, Yamashita, A, Maeda, K, Maeda, Y.
Deposit date:2002-12-03
Release date:2003-07-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
Nature, 424, 2003
8FMS
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BU of 8fms by Molmil
Complex structure of K210 deletion Troponin complex with neridronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.435 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
7UTI
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BU of 7uti by Molmil
ALTERNATIVE MODELING OF TROPOMYOSIN IN HUMAN CARDIAC THIN FILAMENT IN THE CALCIUM BOUND STATE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rynkiewicz, M.J, Pavadai, E, Lehman, W.
Deposit date:2022-04-27
Release date:2022-09-21
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Protein-Protein Docking Reveals Dynamic Interactions of Tropomyosin on Actin Filaments.
Biophys J, 119, 2020
6KN8
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BU of 6kn8 by Molmil
Structure of human cardiac thin filament in the calcium bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Fujii, T, Yamada, Y, Namba, K.
Deposit date:2019-08-03
Release date:2020-01-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cardiac muscle thin filament structures reveal calcium regulatory mechanism.
Nat Commun, 11, 2020
7UTL
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BU of 7utl by Molmil
ALTERNATIVE MODELING OF TROPOMYOSIN IN HUMAN CARDIAC THIN FILAMENT IN THE CALCIUM FREE STATE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rynkiewicz, M.J, Pavadai, E, Lehman, W.
Deposit date:2022-04-27
Release date:2022-09-21
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Protein-Protein Docking Reveals Dynamic Interactions of Tropomyosin on Actin Filaments.
Biophys J, 119, 2020
6KN7
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BU of 6kn7 by Molmil
Structure of human cardiac thin filament in the calcium free state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Fujii, T, Yamada, Y, Namba, K.
Deposit date:2019-08-03
Release date:2020-01-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Cardiac muscle thin filament structures reveal calcium regulatory mechanism.
Nat Commun, 11, 2020

 

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