4OIJ
| X-ray crystal structure of racemic non-glycosylated chemokine Ser-CCL1 | Descriptor: | C-C motif chemokine 1, D-Ser-CCL1, SULFATE ION | Authors: | Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H. | Deposit date: | 2014-01-19 | Release date: | 2014-05-07 | Last modified: | 2014-05-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | (Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis. Angew.Chem.Int.Ed.Engl., 53, 2014
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4OIK
| (Quasi-)Racemic X-ray crystal structure of glycosylated chemokine Ser-CCL1. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1, CITRIC ACID, ... | Authors: | Okamoto, R, Mandal, K, Sawaya, M.R, Kajihara, Y, Yeates, T.O, Kent, S.B.H. | Deposit date: | 2014-01-19 | Release date: | 2014-05-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | (Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis. Angew.Chem.Int.Ed.Engl., 53, 2014
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8TLM
| Structure of a class A GPCR/Fab complex | Descriptor: | C-C chemokine receptor type 8, Green fluorescent protein fusion, Fab heavy chain, ... | Authors: | Sun, D, Johnson, M, Masureel, M. | Deposit date: | 2023-07-27 | Release date: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8. Nat Commun, 14, 2023
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8KFX
| Gi bound CCR8 complex with nonpeptide agonist LMD-009 | Descriptor: | 8-[[3-(2-methoxyphenoxy)phenyl]methyl]-1-(2-phenylethyl)-1,3,8-triazaspiro[4.5]decan-4-one, C-C chemokine receptor type 8,Fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Jiang, S, Lin, X, Wu, L.J, Xu, F. | Deposit date: | 2023-08-16 | Release date: | 2024-02-07 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Unveiling the structural mechanisms of nonpeptide ligand recognition and activation in human chemokine receptor CCR8. Sci Adv, 10, 2024
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8KFY
| Gi bound CCR8 complex with nonpeptide agonist ZK 756326 | Descriptor: | 2-[2-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]ethoxy]ethanol, C-C chemokine receptor type 8,Fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Jiang, S, Lin, X, Wu, L.J, Xu, F. | Deposit date: | 2023-08-16 | Release date: | 2024-02-07 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Unveiling the structural mechanisms of nonpeptide ligand recognition and activation in human chemokine receptor CCR8. Sci Adv, 10, 2024
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8KB4
| Cryo-EM structure of human TMEM87A A308M | Descriptor: | (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 87A,EGFP | Authors: | Han, A, Kim, H.M. | Deposit date: | 2023-08-03 | Release date: | 2024-07-10 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | GolpHCat (TMEM87A), a unique voltage-dependent cation channel in Golgi apparatus, contributes to Golgi-pH maintenance and hippocampus-dependent memory. Nat Commun, 15, 2024
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8U1U
| Structure of a class A GPCR/agonist complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Sun, D, Johnson, M, Masureel, M. | Deposit date: | 2023-09-02 | Release date: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8. Nat Commun, 14, 2023
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7U8G
| Cryo-EM structure of the core human NADPH oxidase NOX2 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7G5 - heavy chain, ... | Authors: | Noreng, S, Ota, N, Sun, Y, Masureel, M, Payandeh, J, Yi, T, Koerber, J.T. | Deposit date: | 2022-03-08 | Release date: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of the core human NADPH oxidase NOX2. Nat Commun, 13, 2022
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8KFZ
| Gi bound CCR8 in ligand free state | Descriptor: | C-C chemokine receptor type 8,LgBiT fusion protein,Recombinant Human Rhinovirus, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Jiang, S, Lin, X, Wu, L.J, Xu, F. | Deposit date: | 2023-08-16 | Release date: | 2024-02-07 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Unveiling the structural mechanisms of nonpeptide ligand recognition and activation in human chemokine receptor CCR8. Sci Adv, 10, 2024
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8HTT
| Cryo-EM structure of human TMEM87A, gluconate-bound | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-gluconic acid, Transmembrane protein 87A,EGFP, ... | Authors: | Han, A, Kim, H.M. | Deposit date: | 2022-12-21 | Release date: | 2023-12-27 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | GolpHCat (TMEM87A), a unique voltage-dependent cation channel in Golgi apparatus, contributes to Golgi-pH maintenance and hippocampus-dependent memory. Nat Commun, 15, 2024
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1EL0
| SOLUTION STRUCTURE OF THE HUMAN CC CHEMOKINE, I-309 | Descriptor: | I-309 | Authors: | Keizer, D.W, Crump, M.P, Lee, T.W, Slupsky, C.M, Clark-Lewis, I, Sykes, B.D. | Deposit date: | 2000-03-11 | Release date: | 2000-09-01 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Human CC chemokine I-309, structural consequences of the additional disulfide bond. Biochemistry, 39, 2000
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