4M9K
 
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4M9M
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4M9T
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1OK8
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5HHG
 | | Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex | | Descriptor: | Importin subunit alpha-1, RNA-directed RNA polymerase NS5 | | Authors: | Smith, K.M, Forwood, J.K. | | Deposit date: | 2016-01-11 | | Release date: | 2016-05-18 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production.
PLoS Pathog., 12, 2016
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1OKE
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1L9K
 | | dengue methyltransferase | | Descriptor: | RNA-DIRECTED RNA POLYMERASE, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION | | Authors: | Egloff, M.P, Benarroch, D, Selisko, B, Romette, J.L, Canard, B. | | Deposit date: | 2002-03-25 | | Release date: | 2003-03-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | An RNA cap (nucleoside-2'-O-) methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
Embo J., 21, 2002
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4M9I
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1R6A
 | | Structure of the dengue virus 2'O methyltransferase in complex with s-adenosyl homocysteine and ribavirin 5' triphosphate | | Descriptor: | Genome polyprotein, RIBAVIRIN MONOPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Benarroch, D, Egloff, M.P, Mulard, L, Romette, J.L, Canard, B. | | Deposit date: | 2003-10-15 | | Release date: | 2004-09-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A structural basis for the inhibition of the NS5 dengue virus mRNA 2'-O-methyltransferase domain by ribavirin 5'-triphosphate.
J.Biol.Chem., 279, 2004
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4M9F
 | | Dengue virus NS2B-NS3 protease A125C variant at pH 8.5 | | Descriptor: | NS2B-NS3 protease | | Authors: | Yildiz, M, Ghosh, S, Bell, J.A, Sherman, W, Hardy, J.A. | | Deposit date: | 2013-08-14 | | Release date: | 2013-11-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus.
Acs Chem.Biol., 8, 2013
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1OAN
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7K93
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2P1D
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4O6B
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6ZQU
 | | Cryo-EM structure of mature Dengue virus 2 at 3.1 angstrom resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein | | Authors: | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | | Deposit date: | 2020-07-10 | | Release date: | 2021-01-20 | | Last modified: | 2021-08-04 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins.
Nat Commun, 12, 2021
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6WY1
 | | Crystal structure of an engineered thermostable dengue virus 2 envelope protein dimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dengue 2 soluble recombinant envelope | | Authors: | Kudlacek, S.T, Lakshmanane, P, Kuhlman, B. | | Deposit date: | 2020-05-12 | | Release date: | 2021-11-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.42 Å) | | Cite: | Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies.
Sci Adv, 7, 2021
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2R69
 | | Crystal structure of Fab 1A1D-2 complexed with E-DIII of Dengue virus at 3.8 angstrom resolution | | Descriptor: | Heavy chain of 1A1D-2, Light chain of 1A1D-2, Major envelope protein E | | Authors: | Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2007-09-05 | | Release date: | 2007-12-25 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
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6WER
 | | DENV2 NS1 in complex with neutralizing 2B7 Fab fragment | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B7 Fab heavy chain, 2B7 Fab light chain, ... | | Authors: | Akey, D.L, Smith, J.L. | | Deposit date: | 2020-04-02 | | Release date: | 2020-12-23 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.96 Å) | | Cite: | Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction.
Science, 371, 2021
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1P58
 | | Complex Organization of Dengue Virus Membrane Proteins as Revealed by 9.5 Angstrom Cryo-EM reconstruction | | Descriptor: | Envelope protein M, Major envelope protein E | | Authors: | Zhang, W, Chipman, P.R, Corver, J, Johnson, P.R, Zhang, Y, Mukhopadhyay, S, Baker, T.S, Strauss, J.H, Rossmann, M.G, Kuhn, R.J. | | Deposit date: | 2003-04-25 | | Release date: | 2003-11-04 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Visualization of membrane protein domains by cryo-electron microscopy of dengue virus
Nat.Struct.Biol., 10, 2003
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1THD
 | | COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION | | Descriptor: | Major envelope protein E | | Authors: | Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2004-06-01 | | Release date: | 2004-09-28 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
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3ZKO
 | | The structure of ''breathing'' dengue virus. | | Descriptor: | ENVELOPE GLYCOPROTEIN | | Authors: | Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Lee, S, Wang, J, Lok, S.M. | | Deposit date: | 2013-01-24 | | Release date: | 2013-05-15 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (13.7 Å) | | Cite: | Structural Changes of Dengue Virus When Exposed to 37 Degrees C.
J.Virol., 87, 2013
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3J8D
 | | Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5 | | Descriptor: | Envelope protein E, antibody E111 Fab fragment, glycoprotein DIII | | Authors: | Zhang, X.Z, Sheng, J, Austin, S.K, Hoornweg, T, Smit, J.M, Kuhn, R.J, Diamond, M.S, Rossmann, M.G. | | Deposit date: | 2014-10-13 | | Release date: | 2014-11-12 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (26 Å) | | Cite: | Structure of Acidic pH Dengue Virus Showing the Fusogenic Glycoprotein Trimers.
J.Virol., 89, 2015
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1R6R
 | | Solution Structure of Dengue Virus Capsid Protein Reveals a New Fold | | Descriptor: | Genome polyprotein | | Authors: | Ma, L, Jones, C.T, Groesch, T.D, Kuhn, R.J, Post, C.B. | | Deposit date: | 2003-10-16 | | Release date: | 2004-02-17 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of dengue virus capsid protein reveals another fold
Proc.Natl.Acad.Sci.USA, 101, 2004
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