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PDB: 73 results

1VQ8
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The structure of CCDA-PHE-CAP-BIO and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(DA)*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQO
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BU of 1vqo by Molmil
The structure of CCPMN bound to the large ribosomal subunit haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(PPU))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQP
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The structure of the transition state analogue "RAP" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*(DC)P*(DC)P*(PPU)*(LOF)P*(PO2)P*AP*C*C)-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQM
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BU of 1vqm by Molmil
The structure of the transition state analogue "DAN" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)P*(PO2)P*(DA)P*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQK
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BU of 1vqk by Molmil
The structure of CCDA-PHE-CAP-BIO bound to the a site of the ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(DA)*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQL
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BU of 1vql by Molmil
The structure of the transition state analogue "DCSN" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(TSE)*(DA)*CP*C)-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
3CC2
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BU of 3cc2 by Molmil
The Refined Crystal Structure of the Haloarcula Marismortui Large Ribosomal Subunit at 2.4 Angstrom Resolution with rrnA Sequence for the 23S rRNA and Genome-derived Sequences for r-Proteins
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Gurel, G, Blaha, G.
Deposit date:2008-02-23
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
1YHQ
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BU of 1yhq by Molmil
Crystal Structure Of Azithromycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui
Descriptor: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
Authors:Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
Deposit date:2005-01-10
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
1FFK
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BU of 1ffk by Molmil
CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI AT 2.4 ANGSTROM RESOLUTION
Descriptor: 23S RRNA, 5S RRNA, CADMIUM ION, ...
Authors:Ban, N, Nissen, P, Hansen, J, Moore, P.B, Steitz, T.A.
Deposit date:2000-07-25
Release date:2000-08-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The complete atomic structure of the large ribosomal subunit at 2.4 A resolution.
Science, 289, 2000
1VQN
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BU of 1vqn by Molmil
The structure of CC-HPMN AND CCA-PHE-CAP-BIO bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(LOF))-3', 5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3', ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.
Nature, 438, 2005
1VQ9
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BU of 1vq9 by Molmil
The structure of CCA-PHE-CAP-BIO and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*AP*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1S72
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BU of 1s72 by Molmil
REFINED CRYSTAL STRUCTURE OF THE HALOARCULA MARISMORTUI LARGE RIBOSOMAL SUBUNIT AT 2.4 ANGSTROM RESOLUTION
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L11P, ...
Authors:Klein, D.J, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2004-01-28
Release date:2004-06-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Roles of Ribosomal Proteins in the Structure, Assembly and Evolution of the Large Ribosomal Subunit
J.Mol.Biol., 340, 2004
1JJ2
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BU of 1jj2 by Molmil
Fully Refined Crystal Structure of the Haloarcula marismortui Large Ribosomal Subunit at 2.4 Angstrom Resolution
Descriptor: 23S RRNA, 5S RRNA, CADMIUM ION, ...
Authors:Klein, D.J, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2001-07-03
Release date:2001-08-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The kink-turn: a new RNA secondary structure motif.
EMBO J., 20, 2001
4V9F
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BU of 4v9f by Molmil
The re-refined crystal structure of the Haloarcula marismortui large ribosomal subunit at 2.4 Angstrom resolution: more complete structure of the L7/L12 and L1 stalk, L5 and LX proteins
Descriptor: 23S Ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Gabdulkhakov, A.
Deposit date:2012-11-02
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Revisiting the Haloarcula marismortui 50S ribosomal subunit model.
Acta Crystallogr.,Sect.D, 69, 2013
1VQ7
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BU of 1vq7 by Molmil
The structure of the transition state analogue "DCA" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(5AA)P*(2OP)P*(PAE)P*AP*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.
Nature, 438, 2005
3CCM
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BU of 3ccm by Molmil
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2611U
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Blaha, G, Gurel, G.
Deposit date:2008-02-26
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
1YIJ
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BU of 1yij by Molmil
Crystal Structure Of Telithromycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui
Descriptor: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
Authors:Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
Deposit date:2005-01-12
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
1VQ5
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BU of 1vq5 by Molmil
The structure of the transition state analogue "RAA" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-D(*(DC)P*(DC)P*(5AA)P*(2OP)P*(PO2)P*AP*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1YI2
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BU of 1yi2 by Molmil
Crystal Structure Of Erythromycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui
Descriptor: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
Authors:Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
Deposit date:2005-01-11
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
3CC4
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BU of 3cc4 by Molmil
Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Blaha, G, Gurel, G.
Deposit date:2008-02-24
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
3CC7
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BU of 3cc7 by Molmil
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation C2487U
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Blaha, G, Gurel, G.
Deposit date:2008-02-25
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
3CPW
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BU of 3cpw by Molmil
The structure of the antibiotic LINEZOLID bound to the large ribosomal subunit of HALOARCULA MARISMORTUI
Descriptor: 23S RIBOSOMAL RNA, 5'-R(*CP*CP*AP*(PHE)*(ACA))-3', 50S ribosomal protein L10E, ...
Authors:Ippolito, J.A, Kanyo, Z.K, Wang, D, Franceschi, F.J, Moore, P.B, Steitz, T.A, Duffy, E.M.
Deposit date:2008-04-01
Release date:2008-07-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
J.Med.Chem., 51, 2008
3G6E
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BU of 3g6e by Molmil
Co-crystal structure of Homoharringtonine bound to the large ribosomal subunit
Descriptor: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 23S ribosomal RNA, 50S ribosomal protein L10E, ...
Authors:Gurel, G, Blaha, G, Moore, P.B, Steitz, T.A.
Deposit date:2009-02-06
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
J.Mol.Biol., 389, 2009
1VQ4
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BU of 1vq4 by Molmil
The structure of the transition state analogue "DAA" bound to the large ribosomal subunit of Haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(5AA)P*(2OP)P*(PO2)P*(DA)P*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
2OTL
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BU of 2otl by Molmil
Girodazole bound to the large subunit of Haloarcula marismortui
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Blaha, G, Schroeder, S.J, Tirado-Rives, J.
Deposit date:2007-02-08
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole.
J.Mol.Biol., 367, 2007

 

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