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PDB: 24 results

1MF7
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BU of 1mf7 by Molmil
INTEGRIN ALPHA M I DOMAIN
Descriptor: INTEGRIN ALPHA M
Authors:McCleverty, C.J, Liddington, R.C.
Deposit date:2002-08-09
Release date:2003-05-20
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003
1NA5
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INTEGRIN ALPHA M I DOMAIN
Descriptor: Integrin alpha-M
Authors:McCleverty, C.J, Liddington, R.C.
Deposit date:2002-11-26
Release date:2003-05-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003
8CE6
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Crystal structure of human Cd11b I domain in P212121 space group
Descriptor: CHLORIDE ION, GLYCEROL, Integrin alpha-M, ...
Authors:Koekemoer, L, Williams, E, Ni, X, Gao, Q, Coker, J, MacLean, E.M, Wright, N.D, Marsden, B, Von Delft, F, Schwenzer, A, Midwood, K.
Deposit date:2023-02-01
Release date:2023-03-22
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.582 Å)
Cite:Crystal structure of human Cd11b I domain in P212121 space group
To Be Published
1IDO
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BU of 1ido by Molmil
I-DOMAIN FROM INTEGRIN CR3, MG2+ BOUND
Descriptor: INTEGRIN, MAGNESIUM ION
Authors:Lee, J.-O, Liddington, R.
Deposit date:1996-03-12
Release date:1996-08-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18).
Cell(Cambridge,Mass.), 80, 1995
1JLM
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I-DOMAIN FROM INTEGRIN CR3, MN2+ BOUND
Descriptor: INTEGRIN, MANGANESE (II) ION
Authors:Lee, J.-O, Liddington, R.
Deposit date:1996-04-09
Release date:1997-01-11
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two conformations of the integrin A-domain (I-domain): a pathway for activation?
Structure, 3, 1995
4XW2
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BU of 4xw2 by Molmil
Structural basis for simvastatin competitive antagonism of complement receptor 3
Descriptor: Integrin alpha-M, MAGNESIUM ION, Simvastatin acid
Authors:Bajic, G, Jensen, M.R, Vorup-Jensen, T, Andersen, G.R.
Deposit date:2015-01-28
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural Basis for Simvastatin Competitive Antagonism of Complement Receptor 3.
J.Biol.Chem., 291, 2016
8CE9
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Crystal structure of human Cd11b I domain in C121 space group
Descriptor: 1,2-ETHANEDIOL, Integrin alpha-M, SULFATE ION
Authors:Koekemoer, L, Williams, E, Ni, X, Gao, Q, Coker, J, MacLean, E.M, Wright, N.D, Marsden, B, Von Delft, F, Schwenzer, A, Midwood, K.
Deposit date:2023-02-01
Release date:2023-03-22
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure of human Cd11b I domain in C121 space group
To Be Published
1M1U
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BU of 1m1u by Molmil
AN ISOLEUCINE-BASED ALLOSTERIC SWITCH CONTROLS AFFINITY AND SHAPE SHIFTING IN INTEGRIN CD11B A-DOMAIN
Descriptor: CALCIUM ION, Integrin alpha-M
Authors:Xiong, J.-P, Li, R, Essafi, M, Stehle, T, Arnaout, M.A.
Deposit date:2002-06-20
Release date:2002-08-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain.
J.Biol.Chem., 275, 2000
1N9Z
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BU of 1n9z by Molmil
INTEGRIN ALPHA M I DOMAIN MUTANT
Descriptor: Integrin alpha-M, MAGNESIUM ION
Authors:McCleverty, C.J, Liddington, R.C.
Deposit date:2002-11-26
Release date:2003-05-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003
1IDN
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MAC-1 I DOMAIN METAL FREE
Descriptor: CD11B
Authors:Baldwin, E.T.
Deposit date:1998-06-10
Release date:1998-11-04
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cation binding to the integrin CD11b I domain and activation model assessment
Structure, 6, 1998
1BHQ
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BU of 1bhq by Molmil
MAC-1 I DOMAIN CADMIUM COMPLEX
Descriptor: ACETYL GROUP, CADMIUM ION, CD11B
Authors:Baldwin, E.T.
Deposit date:1998-06-10
Release date:1998-11-04
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cation binding to the integrin CD11b I domain and activation model assessment
Structure, 6, 1998
1BHO
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BU of 1bho by Molmil
MAC-1 I DOMAIN MAGNESIUM COMPLEX
Descriptor: CD11B, MAGNESIUM ION
Authors:Baldwin, E.T.
Deposit date:1998-06-10
Release date:1998-11-04
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cation binding to the integrin CD11b I domain and activation model assessment
Structure, 6, 1998
7USL
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BU of 7usl by Molmil
Integrin alphaM/beta2 ectodomain in complex with adenylate cyclase toxin RTX751 and M1F5 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2022-04-25
Release date:2022-08-17
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
7USM
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BU of 7usm by Molmil
Integrin alphaM/beta2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2022-04-25
Release date:2022-08-17
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
3Q3G
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BU of 3q3g by Molmil
Crystal Structure of A-domain in complex with antibody
Descriptor: 1,2-ETHANEDIOL, Antibody Heavy chain, Antibody Light Chain, ...
Authors:Mahalingam, B, Xiong, J.P, Arnaout, M.A.
Deposit date:2010-12-21
Release date:2011-11-30
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design.
J.Immunol., 187, 2011
6RHW
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BU of 6rhw by Molmil
Crystal structure of human CD11b I-domain (CD11b-I) in complex with Staphylococcus aureus octameric bi-component leukocidin LukGH
Descriptor: Beta-channel forming cytolysin, DIMETHYL SULFOXIDE, Integrin alpha-M, ...
Authors:Trstenjak, N, Milic, D, Djinovic-Carugo, K, Badarau, A.
Deposit date:2019-04-23
Release date:2019-12-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity.
Proc.Natl.Acad.Sci.USA, 117, 2020
4M76
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BU of 4m76 by Molmil
Integrin I domain of complement receptor 3 in complex with C3d
Descriptor: Complement C3, Integrin alpha-M, NICKEL (II) ION
Authors:Bajic, G, Yatime, L, Vorup-Jensen, T, Andersen, G.R.
Deposit date:2013-08-12
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3.
Proc.Natl.Acad.Sci.USA, 110, 2013
3QA3
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BU of 3qa3 by Molmil
Crystal Structure of A-domain in complex with antibody
Descriptor: 1,2-ETHANEDIOL, Antibody Heavy chain, Antibody Light chain, ...
Authors:Mahalingam, B, Xiong, J.P, Arnaout, M.A.
Deposit date:2011-01-10
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design.
J.Immunol., 187, 2011
7P2D
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BU of 7p2d by Molmil
Structure of alphaMbeta2/Cd11bCD18 headpiece in complex with a nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Jensen, R.K, Andersen, G.R.
Deposit date:2021-07-05
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the function-modulating effects of nanobody binding to the integrin receptor alpha M beta 2.
J.Biol.Chem., 298, 2022
7AKK
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BU of 7akk by Molmil
Structure of a complement factor-receptor complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ...
Authors:Fernandez, F.J, Santos-Lopez, J, Martinez-Barricarte, R, Querol-Garcia, J, Navas-Yuste, S, Savko, M, Shepard, W.E, Rodriguez de Cordoba, S, Vega, M.C.
Deposit date:2020-10-01
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.395 Å)
Cite:The crystal structure of iC3b-CR3 alpha I reveals a modular recognition of the main opsonin iC3b by the CR3 integrin receptor
Nat Commun, 13, 2022
8VOH
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BU of 8voh by Molmil
HADDOCK models of human alphaM I-domain bound to the the N-terminal domain of the cytokine pleiotrophin
Descriptor: Integrin alpha-M, Pleiotrophin
Authors:Wang, X, Nguyen, H.
Deposit date:2024-01-15
Release date:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of alphaM I-domain of integrin Mac-1 in complex with the Cytokine Pleiotrophin
To Be Published
8VOI
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BU of 8voi by Molmil
HADDOCK models of active human alphaM I-domain bound to the the C-terminal domain of the cytokine pleiotrophin
Descriptor: Integrin alpha-M, MAGNESIUM ION, Pleiotrophin
Authors:Wang, X, Nguyen, H.
Deposit date:2024-01-15
Release date:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of alphaM I-domain of integrin Mac-1 in complex with the Cytokine Pleiotrophin
To Be Published
2LKE
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BU of 2lke by Molmil
Structures and Interaction Analyses of the Integrin Alpha-M Beta-2 Cytoplasmic Tails
Descriptor: Integrin alpha-M
Authors:Chua, G.L, Tang, X.Y, Amalraj, M, Bhattacharjya, S, Tan, S.M.
Deposit date:2011-10-11
Release date:2011-11-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structures and interaction analyses of the integrin alphaMbeta2 cytoplasmic tails
J.Biol.Chem., 2011
2LKJ
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BU of 2lkj by Molmil
Structures and Interaction Analyses of the Integrin Alpha-M Beta-2 Cytoplasmic Tails
Descriptor: Integrin alpha-M
Authors:Chua, G.L, Tang, X.Y, Amalraj, M, Tan, S.M, Bhattacharjya, S.
Deposit date:2011-10-12
Release date:2011-11-02
Last modified:2011-11-16
Method:SOLUTION NMR
Cite:Structures and interaction analyses of the integrin alphaMbeta2 cytoplasmic tails
J.Biol.Chem., 2011

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