7AKK

Structure of a complement factor-receptor complex

Summary for 7AKK

• Entry DOI: 10.2210/pdb7akk/pdb
• Descriptor: Complement C3 beta chain, Complement C3b alpha' chain, Integrin alpha-M, ... (10 entities in total)
• Functional Keywords: immunology, complement, ic3b, integrin, cr3, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 393318.38

Authors

Fernandez, F.J.,Santos-Lopez, J.,Martinez-Barricarte, R.,Querol-Garcia, J.,Navas-Yuste, S.,Savko, M.,Shepard, W.E.,Rodriguez de Cordoba, S.,Vega, M.C. (deposition date: 2020-10-01, release date: 2022-04-13, Last modification date: 2024-11-20)

• Primary citation: Fernandez, F.J.,Santos-Lopez, J.,Martinez-Barricarte, R.,Querol-Garcia, J.,Martin-Merinero, H.,Navas-Yuste, S.,Savko, M.,Shepard, W.E.,Rodriguez de Cordoba, S.,Vega, M.C.; The crystal structure of iC3b-CR3 alpha I reveals a modular recognition of the main opsonin iC3b by the CR3 integrin receptor; Nat Commun, 13:1955-, 2022; DOI: 10.1038/s41467-022-29580-2

Experimental method

X-RAY DIFFRACTION (3.395 Å)