3QA3
Crystal Structure of A-domain in complex with antibody
Summary for 3QA3
Entry DOI | 10.2210/pdb3qa3/pdb |
Related | 3Q3G |
Descriptor | Antibody Light chain, Antibody Heavy chain, Integrin alpha-M, ... (7 entities in total) |
Functional Keywords | immune system- cell adhesion complex, immune system/ cell adhesion |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P11215 |
Total number of polymer chains | 12 |
Total formula weight | 282011.89 |
Authors | Mahalingam, B.,Xiong, J.P.,Arnaout, M.A. (deposition date: 2011-01-10, release date: 2011-11-30, Last modification date: 2023-09-13) |
Primary citation | Mahalingam, B.,Ajroud, K.,Alonso, J.L.,Anand, S.,Adair, B.D.,Horenstein, A.L.,Malavasi, F.,Xiong, J.P.,Arnaout, M.A. Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design. J.Immunol., 187:6393-6401, 2011 Cited by PubMed: 22095715DOI: 10.4049/jimmunol.1102394 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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