3QA3
Crystal Structure of A-domain in complex with antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (C, A, F, J) | Antibody Light chain | polymer | 220 | 24457.0 | 4 | Mus musculus | ||
| 2 | B, E, H, K (D, B, H, K) | Antibody Heavy chain | polymer | 224 | 24043.8 | 4 | Mus musculus | ||
| 3 | C, F, I, L (G, E, I, L) | Integrin alpha-M | polymer | 190 | 21722.8 | 4 | UniProt (P11215) Pfam (PF00092) | Homo sapiens (human) | CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor |
| 4 | AA, BA, M, N, P... (J, K, C, D, H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 5 | O, S, T, U, V (D, G, A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 6 | CA, R, W, Y (L, G, E, I) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 7 | DA, EA, FA, GA, HA... (C, D, G, A, B...) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
G, E, I, L: 132 - 321 (UniProt: P11215)
| PDB | External Database | Details |
|---|---|---|
| Gly 316 | Ile 332 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 280894.6 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1117.3 | |
| All* | Total formula weight | 282011.9 |
