2PQ3
 
 | | N-Terminal Calmodulin Zn-Trapped Intermediate | | Descriptor: | CACODYLATE ION, Calmodulin, ZINC ION | | Authors: | Warren, J.T, Guo, Q, Tang, W.J. | | Deposit date: | 2007-05-01 | | Release date: | 2007-10-16 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | A 1.3-A structure of zinc-bound N-terminal domain of calmodulin elucidates potential early ion-binding step.
J.Mol.Biol., 374, 2007
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4J9Y
 | | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant | | Descriptor: | CALCIUM ION, Calmodulin, GLYCEROL, ... | | Authors: | Zhang, M, Pascal, J.M, Zhang, J.-F. | | Deposit date: | 2013-02-17 | | Release date: | 2013-03-27 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Unstructured to structured transition of an intrinsically disordered protein peptide in coupling Ca2+-sensing and SK channel activation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3B32
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1G4Y
 | | 1.60 A CRYSTAL STRUCTURE OF THE GATING DOMAIN FROM SMALL CONDUCTANCE POTASSIUM CHANNEL COMPLEXED WITH CALCIUM-CALMODULIN | | Descriptor: | CALCIUM ION, CALCIUM-ACTIVATED POTASSIUM CHANNEL RSK2, CALMODULIN, ... | | Authors: | Schumacher, M.A, Rivard, A, Bachinger, H.P, Adelman, J.P. | | Deposit date: | 2001-01-07 | | Release date: | 2001-05-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin.
Nature, 410, 2001
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4G28
 | | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and EBIO-1 | | Descriptor: | 1-ethyl-1,3-dihydro-2H-benzimidazol-2-one, CALCIUM ION, Calmodulin, ... | | Authors: | Zhang, M, Pascal, J.M, Zhang, J.-F. | | Deposit date: | 2012-07-11 | | Release date: | 2012-09-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Identification of the functional binding pocket for compounds targeting small-conductance Ca(2+)-activated potassium channels.
Nat Commun, 3, 2012
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4G27
 | | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and phenylurea | | Descriptor: | 1-phenylurea, CALCIUM ION, Calmodulin, ... | | Authors: | Zhang, M, Pascal, J.M, Zhang, J.-F. | | Deposit date: | 2012-07-11 | | Release date: | 2012-09-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Identification of the functional binding pocket for compounds targeting small-conductance Ca(2+)-activated potassium channels.
Nat Commun, 3, 2012
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4J9Z
 | | Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and NS309 | | Descriptor: | (3E)-6,7-dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin, ... | | Authors: | Zhang, M, Pascal, J.M, Zhang, J.-F. | | Deposit date: | 2013-02-17 | | Release date: | 2013-03-27 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Unstructured to structured transition of an intrinsically disordered protein peptide in coupling Ca2+-sensing and SK channel activation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3SG6
 | | Crystal Structure of Dimeric GCaMP2-LIA(linker 1) | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | | Deposit date: | 2011-06-14 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
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3EVU
 | | Crystal structure of Calcium bound dimeric GCAMP2 | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H. | | Deposit date: | 2008-10-13 | | Release date: | 2008-12-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural Basis for Calcium Sensing by GCaMP2.
Structure, 16, 2008
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6MBA
 | | Crystal Structure of Human Nav1.4 CTerminal Domain in Complex with apo Calmodulin | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CARBONATE ION, ... | | Authors: | Yoder, J, Gabelli, S.B, Amzel, L.M. | | Deposit date: | 2018-08-29 | | Release date: | 2019-04-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.799 Å) | | Cite: | Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.
Nat Commun, 10, 2019
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3EK7
 | | Calcium-saturated GCaMP2 dimer | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | | Deposit date: | 2008-09-18 | | Release date: | 2008-12-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design
J.Biol.Chem., 284, 2009
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3SJQ
 | | Crystal structure of a small conductance potassium channel splice variant complexed with calcium-calmodulin | | Descriptor: | 1-phenylurea, CALCIUM ION, Calmodulin, ... | | Authors: | Zhang, M, Pascal, J.M, Zhang, J.-F. | | Deposit date: | 2011-06-21 | | Release date: | 2012-05-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for calmodulin as a dynamic calcium sensor.
Structure, 20, 2012
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3SG5
 | | Crystal Structure of Dimeric GCaMP3-D380Y, QP(linker 1), LP(linker 2) | | Descriptor: | CALCIUM ION, GLYCEROL, Myosin light chain kinase, ... | | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | | Deposit date: | 2011-06-14 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
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3SG7
 | | Crystal Structure of GCaMP3-KF(linker 1) | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | | Deposit date: | 2011-06-14 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
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2HQW
 | | Crystal Structure of Ca2+/Calmodulin bound to NMDA Receptor NR1C1 peptide | | Descriptor: | CALCIUM ION, Calmodulin, Glutamate NMDA receptor subunit zeta 1 | | Authors: | Akyol, Z, Gakhar, L, Sorensen, B.R, Hell, J.H, Shea, M.A. | | Deposit date: | 2006-07-19 | | Release date: | 2007-11-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The NMDA Receptor NR1 C1 Region Bound to Calmodulin: Structural Insights into Functional Differences between Homologous Domains.
Structure, 15, 2007
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4EHQ
 | | Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+/Calmodulin Displays a Unique Binding Mode | | Descriptor: | CALCIUM ION, Calcium release-activated calcium channel protein 1, Calmodulin, ... | | Authors: | Liu, Y, Zheng, X, Mueller, G.A, Sobhany, M, DeRose, E.F, Zhang, Y, London, R.E, Birnbaumer, L. | | Deposit date: | 2012-04-03 | | Release date: | 2012-11-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.9005 Å) | | Cite: | Crystal structure of calmodulin binding domain of orai1 in complex with ca2+*calmodulin displays a unique binding mode.
J.Biol.Chem., 287, 2012
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3EVR
 | | Crystal structure of Calcium bound monomeric GCAMP2 | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H. | | Deposit date: | 2008-10-13 | | Release date: | 2008-12-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for Calcium Sensing by GCaMP2.
Structure, 16, 2008
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4RJD
 | | TFP bound in alternate orientations to calcium-saturated Calmodulin C-Domains | | Descriptor: | 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Feldkamp, M.D, Gakhar, L, Pandey, N, Shea, M.A. | | Deposit date: | 2014-10-08 | | Release date: | 2015-08-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Opposing orientations of the anti-psychotic drug trifluoperazine selected by alternate conformations of M144 in calmodulin.
Proteins, 83, 2015
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3EKH
 | | Calcium-saturated GCaMP2 T116V/K378W mutant monomer | | Descriptor: | CALCIUM ION, GLYCEROL, Myosin light chain kinase, ... | | Authors: | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | | Deposit date: | 2008-09-19 | | Release date: | 2008-12-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design
J.Biol.Chem., 284, 2009
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3SG2
 | | Crystal Structure of GCaMP2-T116V,D381Y | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | | Deposit date: | 2011-06-14 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
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3IFK
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4OY4
 | | calcium-free CaMPARI v0.2 | | Descriptor: | Chimera protein of Calmodulin, GPF-like protein EosFP, and Myosin light chain kinase, ... | | Authors: | Fosque, B.F, Schreiter, E.R. | | Deposit date: | 2014-02-10 | | Release date: | 2015-02-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Neural circuits. Labeling of active neural circuits in vivo with designed calcium integrators.
Science, 347, 2015
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1NIW
 | | Crystal structure of endothelial nitric oxide synthase peptide bound to calmodulin | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Nitric-oxide synthase, ... | | Authors: | Aoyagi, M, Arvai, A.S, Tainer, J.A, Getzoff, E.D. | | Deposit date: | 2002-12-26 | | Release date: | 2003-02-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis for endothelial nitric oxide synthase binding to calmodulin
Embo J., 22, 2003
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3SG3
 | | Crystal Structure of GCaMP3-D380Y | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | | Deposit date: | 2011-06-14 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
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4I2Y
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