6XH2
 
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1NU4
 | | U1A RNA binding domain at 1.8 angstrom resolution reveals a pre-organized C-terminal helix | | Descriptor: | MAGNESIUM ION, MALONIC ACID, U1A RNA binding domain | | Authors: | Rupert, P.B, Xiao, H, Ferre-D'Amare, A.R. | | Deposit date: | 2003-01-30 | | Release date: | 2003-02-14 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | U1A RNA-binding domain at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
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6SQT
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6SR7
 | | Structure of the U1A variant A1-98 Y31H/Q36R/K98W | | Descriptor: | SULFATE ION, U1 small nuclear ribonucleoprotein A | | Authors: | Rosenbach, H, Span, I. | | Deposit date: | 2019-09-05 | | Release date: | 2020-05-13 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
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1URN
 | | U1A MUTANT/RNA COMPLEX + GLYCEROL | | Descriptor: | CHLORIDE ION, GLYCEROL, PROTEIN (U1A), ... | | Authors: | Oubridge, C, Ito, N, Evans, P.R, Teo, C.-H, Nagai, K. | | Deposit date: | 1995-01-04 | | Release date: | 1996-03-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin.
Nature, 372, 1994
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6SQN
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4YB1
 | | 20A Mutant c-di-GMP Vc2 Riboswitch bound with 3',3'-cGAMP | | Descriptor: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, MAGNESIUM ION, RNA (91-MER), ... | | Authors: | Ren, A.M, Patel, D.J, Rajashankar, R.K. | | Deposit date: | 2015-02-18 | | Release date: | 2015-04-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.081 Å) | | Cite: | Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch.
Cell Rep, 11, 2015
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8GXB
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7QR3
 | | Chimpanzee CPEB3 HDV-like ribozyme | | Descriptor: | GLYCEROL, POTASSIUM ION, U1 small nuclear ribonucleoprotein A, ... | | Authors: | Przytula-Mally, A.I, Engilberge, S, Johannsen, S, Olieric, V, Masquida, B, Sigel, R.K.O. | | Deposit date: | 2022-01-10 | | Release date: | 2022-10-26 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Anticodon-like loop-mediated dimerization in the crystal structures of HdV-like CPEB3 ribozymes
Biorxiv, 2022
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1SJ3
 | | Hepatitis Delta Virus Gemonic Ribozyme Precursor, with Mg2+ Bound | | Descriptor: | MAGNESIUM ION, precursor form of the Hepatitis Delta virus ribozyme, small nuclear ribonucleoprotein A | | Authors: | Ke, A, Zhou, K, Ding, F, Cate, J.H, Doudna, J.A. | | Deposit date: | 2004-03-02 | | Release date: | 2004-05-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A Conformational Switch controls hepatitis delta virus ribozyme
catalysis
Nature, 429, 2004
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7LHX
 | | Human U1A protein with F37M and F77M mutations for improved phasing | | Descriptor: | ACETATE ION, BETA-MERCAPTOETHANOL, SODIUM ION, ... | | Authors: | Jenkins, J.L, Lippa, G.M, Wedekind, J.E. | | Deposit date: | 2021-01-26 | | Release date: | 2021-03-17 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing
Crystals, 11, 2021
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3EGZ
 | | Crystal structure of an in vitro evolved tetracycline aptamer and artificial riboswitch | | Descriptor: | 7-CHLOROTETRACYCLINE, MAGNESIUM ION, Tetracycline aptamer and artificial riboswitch, ... | | Authors: | Xiao, H, Edwards, T.E, Ferre-D'Amare, A.R. | | Deposit date: | 2008-09-11 | | Release date: | 2008-10-28 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch
Chem.Biol., 15, 2008
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1M5O
 | | Transition State Stabilization by a Catalytic RNA | | Descriptor: | CALCIUM ION, RNA SUBSTRATE, RNA HAIRPIN RIBOZYME, ... | | Authors: | Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R. | | Deposit date: | 2002-07-09 | | Release date: | 2002-10-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Transition state stabilization by a catalytic RNA
Science, 298, 2002
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1DRZ
 | | U1A SPLICEOSOMAL PROTEIN/HEPATITIS DELTA VIRUS GENOMIC RIBOZYME COMPLEX | | Descriptor: | MAGNESIUM ION, PROTEIN (U1 SMALL RIBONUCLEOPROTEIN A), RNA (HEPATITIS DELTA VIRUS GENOMIC RIBOZYME), ... | | Authors: | Ferre-D'Amare, A.R, Zhou, K, Doudna, J.A. | | Deposit date: | 1998-09-01 | | Release date: | 1999-02-16 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of a hepatitis delta virus ribozyme.
Nature, 395, 1998
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4PR6
 | | A Second Look at the HDV Ribozyme Structure and Dynamics. | | Descriptor: | HDV RIBOZYME SELF-CLEAVED, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A | | Authors: | Kapral, G.J, Jain, S, Noeske, J, Doudna, J.A, Richardson, D.C, Richardson, J.S. | | Deposit date: | 2014-03-05 | | Release date: | 2014-10-29 | | Last modified: | 2014-11-26 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | New tools provide a second look at HDV ribozyme structure, dynamics and cleavage.
Nucleic Acids Res., 42, 2014
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3MXH
 | | Native structure of a c-di-GMP riboswitch from V. cholerae | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ... | | Authors: | Strobel, S.A, Smith, K.D. | | Deposit date: | 2010-05-07 | | Release date: | 2010-08-25 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch .
Biochemistry, 49, 2010
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5DDP
 | | L-glutamine riboswitch bound with L-glutamine | | Descriptor: | GLUTAMINE, MAGNESIUM ION, RNA (61-MER), ... | | Authors: | Ren, A, Patel, D.J. | | Deposit date: | 2015-08-25 | | Release date: | 2015-12-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.302 Å) | | Cite: | Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
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6XH3
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6SQQ
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4PRF
 | | A Second Look at the HDV Ribozyme Structure and Dynamics. | | Descriptor: | Hepatitis Delta virus ribozyme, STRONTIUM ION, U1 small nuclear ribonucleoprotein A | | Authors: | Kapral, G.J, Jain, S, Noeske, J, Doudna, J.A, Richardson, D.C, Richardson, J.S. | | Deposit date: | 2014-03-05 | | Release date: | 2014-10-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.395 Å) | | Cite: | New tools provide a second look at HDV ribozyme structure, dynamics and cleavage.
Nucleic Acids Res., 42, 2014
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1M5K
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1M5V
 | | Transition State Stabilization by a Catalytic RNA | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, RNA HAIRPIN RIBOZYME, ... | | Authors: | Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R. | | Deposit date: | 2002-07-09 | | Release date: | 2002-10-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Transition state stabilization by a catalytic RNA
Science, 298, 2002
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2OIH
 | | Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+ | | Descriptor: | HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A | | Authors: | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | | Deposit date: | 2007-01-11 | | Release date: | 2007-03-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
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5DDQ
 | | L-glutamine riboswitch bound with L-glutamine soaked with Mn2+ | | Descriptor: | GLUTAMINE, L-glutamine riboswitch RNA (61-MER), MAGNESIUM ION, ... | | Authors: | Ren, A, Patel, D.J. | | Deposit date: | 2015-08-25 | | Release date: | 2015-12-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
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1OIA
 | | U1A rnp domain 1-95 | | Descriptor: | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | | Authors: | Nagai, K, Evans, P.R. | | Deposit date: | 2003-06-12 | | Release date: | 2003-06-26 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of the RNA-Binding Domain of the U1 Small Nuclear Ribonucleoprotein A
Nature, 348, 1990
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