6VTM
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8G25
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1CGH
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![BU of 1cgh by Molmil](/molmil-images/mine/1cgh) | Human cathepsin G | Descriptor: | CATHEPSIN G, N-(3-carboxypropanoyl)-L-valyl-N-{(1R)-1-[(S)-hydroxy(oxido)phosphanyl]-2-phenylethyl}-L-prolinamide | Authors: | Hof, P, Bode, W. | Deposit date: | 1996-06-26 | Release date: | 1997-07-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities. EMBO J., 15, 1996
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8G24
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1T32
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![BU of 1t32 by Molmil](/molmil-images/mine/1t32) | A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation | Descriptor: | 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, Cathepsin G, SULFATE ION | Authors: | de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E. | Deposit date: | 2004-04-23 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J.Biol.Chem., 280, 2005
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8G26
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8D4V
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![BU of 8d4v by Molmil](/molmil-images/mine/8d4v) | Crystal Structure of Cathepsin G Inhibited by Eap2 from S. aureus | Descriptor: | Cathepsin G, C-terminal truncated form, Extracellular Adherence Protein, ... | Authors: | Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. | Deposit date: | 2022-06-02 | Release date: | 2022-12-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299, 2023
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1AU8
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![BU of 1au8 by Molmil](/molmil-images/mine/1au8) | HUMAN CATHEPSIN G | Descriptor: | CATHEPSIN G, N-(3-carboxypropanoyl)-L-valyl-N-[(1R)-5-amino-1-phosphonopentyl]-L-prolinamide | Authors: | Medrano, F.J, Bode, W, Banbula, A, Potempa, J. | Deposit date: | 1997-09-12 | Release date: | 1998-10-14 | Last modified: | 2012-12-12 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | HUMAN CATHEPSIN G to be published
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8D4S
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![BU of 8d4s by Molmil](/molmil-images/mine/8d4s) | Crystal Structure of Cathepsin G Inhibited by Eap1 from S. aureus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin G, C-terminal truncated form, ... | Authors: | Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. | Deposit date: | 2022-06-02 | Release date: | 2022-12-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299, 2023
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9ASX
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9ATK
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8D7K
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1KYN
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![BU of 1kyn by Molmil](/molmil-images/mine/1kyn) | Cathepsin-G | Descriptor: | (2-NAPHTHALEN-2-YL-1-NAPHTHALEN-1-YL-2-OXO-ETHYL)-PHOSPHONIC ACID, cathepsin G | Authors: | Greco, M.N, Hawkins, M.J, Powell, E.T, Almond Jr, H.R, Corcoran, T.W, De Garavilla, L, Kauffman, J.A, Recacha, R, Chattopadhyay, D, Andrade-Gordon, P, Maryanoff, B.E. | Deposit date: | 2002-02-05 | Release date: | 2002-05-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design. J.Am.Chem.Soc., 124, 2002
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8D7I
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