1CGH

Human cathepsin G

Summary for 1CGH

Related PRD IDPRD_000399
DescriptorCATHEPSIN G, N-(3-carboxypropanoyl)-L-valyl-N-{(1R)-1-[(S)-hydroxy(oxido)phosphanyl]-2-phenylethyl}-L-prolinamide (3 entities in total)
Functional Keywordsinflammation, specificity, serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCell surface P08311
Total number of polymer chains1
Total molecular weight25981.69
Authors
Hof, P.,Bode, W. (deposition date: 1996-06-26, release date: 1997-07-07, Last modification date: 2012-12-12)
Primary citation
Hof, P.,Mayr, I.,Huber, R.,Korzus, E.,Potempa, J.,Travis, J.,Powers, J.C.,Bode, W.
The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities.
EMBO J., 15:5481-5491, 1996
PubMed: 8896442 (PDB entries with the same primary citation)
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers70.9%6.8%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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