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PDB: 13 results

1DX5
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Crystal structure of the thrombin-thrombomodulin complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FORMIC ACID, ...
Authors:Fuentes-Prior, P, Iwanaga, Y, Huber, R, Pagila, R, Rumennik, G, Seto, M, Morser, J, Light, D.R, Bode, W.
Deposit date:1999-12-20
Release date:2000-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex
Nature, 404, 2000
5TO3
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Crystal structure of thrombin mutant W215A/E217A fused to EGF456 of thrombomodulin via a 31-residue linker and bound to PPACK
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Barranco-Medina, S, Murphy, M, Pelc, L, Chen, Z, Di Cera, E, Pozzi, N.
Deposit date:2016-10-16
Release date:2017-03-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Rational Design of Protein C Activators.
Sci Rep, 7, 2017
3GIS
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Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin
Descriptor: CALCIUM ION, Prothrombin, SULFATE ION, ...
Authors:Adams, T.E, Huntington, J.A.
Deposit date:2009-03-06
Release date:2009-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis of thrombomodulin activation of slow thrombin
J.Thromb.Haemost., 7, 2009
1HLT
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BU of 1hlt by Molmil
THE STRUCTURE OF A NONADECAPEPTIDE OF THE FIFTH EGF DOMAIN OF THROMBOMODULIN COMPLEXED WITH THROMBIN
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-08-28
Release date:1994-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a nonadecapeptide of the fifth EGF domain of thrombomodulin complexed with thrombin.
Biochemistry, 33, 1994
7T4R
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CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with THBD and neutralizing fabs MSL-109 and 13H11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
Authors:Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C.
Deposit date:2021-12-10
Release date:2022-03-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
Sci Adv, 8, 2022
1DQB
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NMR STRUCTURE OF THROMBOMODULIN EGF(4-5)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, THROMBOMODULIN
Authors:Wood, M.J, Sampoli-Benitez, B.A, Komives, E.A.
Deposit date:2000-01-03
Release date:2000-03-06
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Solution structure of the smallest cofactor-active fragment of thrombomodulin.
Nat.Struct.Biol., 7, 2000
1FGE
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EPIDERMAL GROWTH FACTOR (EGF) SUBDOMAIN OF HUMAN THROMBOMODULIN (NMR, 14 STRUCTURES)
Descriptor: THROMBOMODULIN
Authors:Hrabal, R, Komives, E.A, Ni, F.
Deposit date:1995-11-28
Release date:1996-06-20
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural resiliency of an EGF-like subdomain bound to its target protein, thrombin.
Protein Sci., 5, 1996
1FGD
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EPIDERMAL GROWTH FACTOR (EGF) SUBDOMAIN OF HUMAN THROMBOMODULIN (NMR, 11 STRUCTURES)
Descriptor: THROMBOMODULIN
Authors:Hrabal, R, Komives, E.A, Ni, F.
Deposit date:1995-11-28
Release date:1996-06-20
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural resiliency of an EGF-like subdomain bound to its target protein, thrombin.
Protein Sci., 5, 1996
1EGT
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BU of 1egt by Molmil
THROMBIN-BOUND STRUCTURE OF AN EGF SUBDOMAIN FROM HUMAN THROMBOMODULIN DETERMINED BY TRANSFERRED NUCLEAR OVERHAUSER EFFECTS
Descriptor: THROMBOMODULIN
Authors:Ni, F.
Deposit date:1994-10-12
Release date:1995-11-15
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Thrombin-bound structure of an EGF subdomain from human thrombomodulin determined by transferred nuclear Overhauser effects.
Biochemistry, 33, 1994
1TMR
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BU of 1tmr by Molmil
THE STRUCTURE OF A 19 RESIDUE FRAGMENT FROM THE C-LOOP OF THE FOURTH EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF THROMBOMODULIN
Descriptor: THROMBOMODULIN PRECURSOR
Authors:Adler, M, Seto, M, Nitecki, D, Light, D.R, Morser, J.
Deposit date:1994-05-20
Release date:1995-06-08
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:The structure of a 19-residue fragment from the C-loop of the fourth epidermal growth factor-like domain of thrombomodulin.
J.Biol.Chem., 270, 1995
1ADX
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FIFTH EGF-LIKE DOMAIN OF THROMBOMODULIN (TMEGF5), NMR, 14 STRUCTURES
Descriptor: THROMBOMODULIN
Authors:Sampoli-Benitez, B.A, Hunter, M.J, Meininger, D.P, Komives, E.A.
Deposit date:1997-02-18
Release date:1997-12-24
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structure of the fifth EGF-like domain of thrombomodulin: An EGF-like domain with a novel disulfide-bonding pattern.
J.Mol.Biol., 273, 1997
1ZAQ
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BU of 1zaq by Molmil
FOURTH EGF-LIKE DOMAIN OF THROMBOMODULIN, NMR, 12 STRUCTURES
Descriptor: THROMBOMODULIN
Authors:Meininger, D.P, Komives, E.A.
Deposit date:1995-09-09
Release date:1996-01-29
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Synthesis, Activity, and Preliminary Structure of the Fourth Egf-Like Domain of Thrombomodulin
Protein Sci., 4, 1995
2ADX
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FIFTH EGF-LIKE DOMAIN OF THROMBOMODULIN (TMEGF5), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: THROMBOMODULIN
Authors:Sampoli-Benitez, B.A, Hunter, M.J, Meininger, D.P, Komives, E.A.
Deposit date:1997-02-18
Release date:1997-12-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structure of the fifth EGF-like domain of thrombomodulin: An EGF-like domain with a novel disulfide-bonding pattern.
J.Mol.Biol., 273, 1997

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