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PDB: 101 results

8CCS
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BU of 8ccs by Molmil
80S S. cerevisiae ribosome with ligands in hybrid-1 pre-translocation (PRE-H1) complex
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-01-27
Release date:2023-09-20
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (1.97 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
6ZQH
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BU of 6zqh by Molmil
Yeast Uba1 in complex with ubiquitin
Descriptor: BETA-MERCAPTOETHANOL, GLYCEROL, TETRAETHYLENE GLYCOL, ...
Authors:Misra, M, Schindelin, H.
Deposit date:2020-07-09
Release date:2020-11-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.032 Å)
Cite:Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection.
Chemistry, 27, 2021
8CDR
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BU of 8cdr by Molmil
Translocation intermediate 2 (TI-2) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-01-31
Release date:2023-09-20
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.04 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
5L6H
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BU of 5l6h by Molmil
Uba1 in complex with Ub-ABPA3 covalent adduct
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Misra, M, Schindelin, H.
Deposit date:2016-05-30
Release date:2017-06-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme.
Structure, 25, 2017
7ZW0
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BU of 7zw0 by Molmil
FAP-80S Complex - Rotated state
Descriptor: 18S ribosomal RNA (RDN18-1), 25S ribosomal RNA (RDN25-1), 40S ribosomal protein S0-A, ...
Authors:Ikeuchi, K, Buschauer, R, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2022-05-17
Release date:2022-10-05
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover.
Mol.Cell, 82, 2022
5U4P
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BU of 5u4p by Molmil
Protein-protein complex between 26S proteasome regulatory subunit RPN8, RPN11, and Ubiquitin S31
Descriptor: 26S proteasome regulatory subunit RPN11, 26S proteasome regulatory subunit RPN8, Ubiquitin-40S ribosomal protein S31, ...
Authors:Worden, E.J, Dong, K.C, Martin, A.
Deposit date:2016-12-05
Release date:2017-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An AAA Motor-Driven Mechanical Switch in Rpn11 Controls Deubiquitination at the 26S Proteasome.
Mol. Cell, 67, 2017
7ZUX
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BU of 7zux by Molmil
Collided ribosome in a disome unit from S. cerevisiae
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
Deposit date:2022-05-13
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
6T4Q
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BU of 6t4q by Molmil
Structure of yeast 80S ribosome stalled on the CGA-CCG inhibitory codon combination.
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R.
Deposit date:2019-10-14
Release date:2019-12-25
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
5L6J
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BU of 5l6j by Molmil
Uba1 in complex with Ub-MLN7243 covalent adduct
Descriptor: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
Authors:Misra, M, Schindelin, H.
Deposit date:2016-05-30
Release date:2017-06-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme.
Structure, 25, 2017
7MPJ
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BU of 7mpj by Molmil
Stm1 bound vacant 80S structure isolated from wild-type
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Rai, J, Zhao, Y, Li, H.
Deposit date:2021-05-04
Release date:2022-05-11
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.
Structure, 30, 2022
8CDL
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BU of 8cdl by Molmil
80S S. cerevisiae ribosome with ligands in hybrid-2 pre-translocation (PRE-H2) complex
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-01-31
Release date:2023-09-20
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
5L6I
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BU of 5l6i by Molmil
Uba1 in complex with Ub-MLN4924 covalent adduct
Descriptor: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
Authors:Misra, M, Schindelin, H.
Deposit date:2016-05-30
Release date:2017-06-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme.
Structure, 25, 2017
3L0W
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BU of 3l0w by Molmil
Structure of split monoubiquitinated PCNA with ubiquitin in position two
Descriptor: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
Deposit date:2009-12-10
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
3L10
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BU of 3l10 by Molmil
Structure of split monoubiquitinated PCNA with ubiquitin in position one
Descriptor: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
Deposit date:2009-12-10
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
6TB3
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BU of 6tb3 by Molmil
yeast 80S ribosome in complex with the Not5 subunit of the CCR4-NOT complex
Descriptor: 25S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Buschauer, R, Cheng, J, Berninghausen, O, Tesina, P, Becker, T, Beckmann, R.
Deposit date:2019-10-31
Release date:2020-04-22
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Science, 368, 2020
6SNT
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BU of 6snt by Molmil
Yeast 80S ribosome stalled on SDD1 mRNA.
Descriptor: 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, 40S ribosomal protein S10-A, ...
Authors:Tesina, P, Buschauer, R, Cheng, J, Becker, T, Beckmann, R.
Deposit date:2019-08-27
Release date:2020-03-04
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.
Nat.Struct.Mol.Biol., 27, 2020
4U4R
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BU of 4u4r by Molmil
Crystal structure of Lactimidomycin bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione, ...
Authors:Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U3U
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BU of 4u3u by Molmil
Crystal structure of Cycloheximide bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
Deposit date:2014-07-22
Release date:2014-10-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
6WOO
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BU of 6woo by Molmil
CryoEM structure of yeast 80S ribosome with Met-tRNAiMet, eIF5B, and GDP
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal rRNA, ...
Authors:Wang, J, Wang, J, Puglisi, J, Fernandez, I.S.
Deposit date:2020-04-25
Release date:2020-09-23
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:An active role of the eukaryotic large ribosomal subunit in translation initiation fidelity.
To Be Published
4V88
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BU of 4v88 by Molmil
The structure of the eukaryotic ribosome at 3.0 A resolution.
Descriptor: 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ...
Authors:Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M.
Deposit date:2011-10-11
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the eukaryotic ribosome at 3.0 angstrom resolution.
Science, 334, 2011
7A1G
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BU of 7a1g by Molmil
Structure of a crosslinked yeast ABCE1-bound 43S pre-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Mackens-Kiani, T, Kratzat, H, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-08-13
Release date:2020-10-14
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
8C83
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BU of 8c83 by Molmil
Cryo-EM structure of in vitro reconstituted Otu2-bound Ub-40S complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-18
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8CAH
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BU of 8cah by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-24
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
4U52
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BU of 4u52 by Molmil
Crystal structure of Nagilactone C bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U3M
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BU of 4u3m by Molmil
Crystal structure of Anisomycin bound to the yeast 80S ribosome
Descriptor: 18S rRNA, 25s rRNA, 40S ribosomal protein S0-A, ...
Authors:Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
Deposit date:2014-07-22
Release date:2014-10-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014

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