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PDB: 382 results

3GIV
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BU of 3giv by Molmil
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Descriptor: Beta-2-microglobulin, HIV-1 peptide, HLA class I histocompatibility antigen, ...
Authors:Stewart-Jones, G, Iversen, A.K.N, Jones, E.Y.
Deposit date:2009-03-06
Release date:2009-06-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Nat.Immunol., 10, 2009
4K7F
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BU of 4k7f by Molmil
Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201
Descriptor: Beta-2-microglobulin, Core protein, HLA class I histocompatibility antigen, ...
Authors:Meng, S.D, Zhang, Y, Wu, Y, Qi, J.X.
Deposit date:2013-04-17
Release date:2013-06-05
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:The L60V variation in hepatitis B virus core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication.
J.Virol., 87, 2013
3HPJ
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BU of 3hpj by Molmil
Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2009-06-04
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics.
Mol.Immunol., 47, 2010
2CLR
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BU of 2clr by Molmil
THREE DIMENSIONAL STRUCTURE OF A PEPTIDE EXTENDING OUT ONE END OF A CLASS I MHC BINDING SITE
Descriptor: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) (ALPHA CHAIN), DECAMERIC PEPTIDE FROM CALRETICULIN
Authors:Collins, E.J, Garboczi, D.N, Wiley, D.C.
Deposit date:1994-08-01
Release date:1995-03-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of a peptide extending from one end of a class I MHC binding site.
Nature, 371, 1994
3V5D
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BU of 3v5d by Molmil
HLA-A2.1 KVAELVHFL
Descriptor: Beta-2-microglobulin, HIV peptide KVAELVHFL, HLA class I histocompatibility antigen, ...
Authors:Collins, E.J, Lee, H.Y.
Deposit date:2011-12-16
Release date:2012-12-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Prediction of conformation and immunogenicity of peptides bound to MHC molecules
To be Published
5SWQ
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BU of 5swq by Molmil
Crystal Structure of HLA-A*0201 in complex with NA231, an influenza epitope
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Josephs, T.M, Rossjohn, J, Gras, S.
Deposit date:2016-08-08
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Lack of Heterologous Cross-reactivity toward HLA-A*02:01 Restricted Viral Epitopes Is Underpinned by Distinct alpha beta T Cell Receptor Signatures.
J.Biol.Chem., 291, 2016
3H9H
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Human Class I MHC HLA-A2(A150P) in complex with the Tel1p peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2009-04-30
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
4NQX
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BU of 4nqx by Molmil
Crystal Structure of HLA A*0101 in complex with NP44-S7N, an 9-mer influenza epitope
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-1 alpha chain, ...
Authors:Rossjohn, J, Gras, S.
Deposit date:2013-11-26
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities.
Proc.Natl.Acad.Sci.USA, 111, 2014
3RL1
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BU of 3rl1 by Molmil
HIV RT derived peptide complexed to HLA-A*0301
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-3 alpha chain, ...
Authors:Zhang, S, Liu, J, Cheng, H, Tan, S, Qi, J, Yan, J, Gao, G.F.
Deposit date:2011-04-19
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
4NO2
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BU of 4no2 by Molmil
Crystal structure of RQA_V phosphopeptide bound to HLA-A2
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Mohammed, F, Stones, D.H, Willcox, B.E.
Deposit date:2013-11-19
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
1T1Y
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BU of 1t1y by Molmil
Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-5V
Descriptor: Beta-2-microglobulin, GAG PEPTIDE, HLA class I histocompatibility antigen, ...
Authors:Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y.
Deposit date:2004-04-19
Release date:2005-09-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes.
J.Biol.Chem., 281, 2006
5EU6
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BU of 5eu6 by Molmil
HLA Class I antigen
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
Deposit date:2015-11-18
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5C0B
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BU of 5c0b by Molmil
1E6 TCR in complex with HLA-A02 carrying RQFGPDFPTI
Descriptor: 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ...
Authors:Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5HHN
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BU of 5hhn by Molmil
Crystal Structure of HLA-A*0201 in complex with M1-F5L
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Gras, S, Josephs, T.M, Rossjohn, J.
Deposit date:2016-01-11
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.
Proc.Natl.Acad.Sci.USA, 113, 2016
5YXN
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BU of 5yxn by Molmil
A T cell receptor in complex with HLA-A0201 restricted Hepatitis C virus NS3 peptide (KLVALGINAV)
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Hui, F.
Deposit date:2017-12-06
Release date:2018-12-12
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Capturing HCV immune escape by targeting structural based mechanism
To Be Published
7L1B
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BU of 7l1b by Molmil
Crystal structure of HLA-A*03:01 in complex with a wild-type PIK3CA peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2020-12-14
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
2AV7
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BU of 2av7 by Molmil
Crystal structure of HTLV-1 TAX peptide Bound to Human Class I MHC HLA-A2 with the K66A mutation in the heavy chain.
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2005-08-29
Release date:2005-10-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants.
J.Mol.Biol., 353, 2005
8RYO
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BU of 8ryo by Molmil
Structure of S2-198 TCR in complex with HLA-A*03:01 bound to ELFSYLIEK peptide
Descriptor: 1,2-ETHANEDIOL, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, Beta-2-microglobulin, ...
Authors:Karuppiah, V.
Deposit date:2024-02-09
Release date:2024-09-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of S2-198 TCR in complex with HLA-A*03:01 bound to ELFSYLIEK peptide
To Be Published
5ISZ
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BU of 5isz by Molmil
Crystal structure of LS01-TCR/M1-HLA-A*02 complex
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Stern, L.J, Selin, L.K, Song, I.
Deposit date:2016-03-15
Release date:2017-03-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8(+) T cell epitope.
Nat. Struct. Mol. Biol., 24, 2017
5HGD
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BU of 5hgd by Molmil
HLA*A2402 complexed with HIV nef138 Y2F mutant 10mer epitope
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
Authors:Shi, Y, Qi, J, Gao, G.F.
Deposit date:2016-01-08
Release date:2016-06-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Effects of a Single Escape Mutation on T Cell and HIV-1 Co-adaptation.
Cell Rep, 15, 2016
5D2N
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BU of 5d2n by Molmil
Crystal structure of C25-NLV-HLA-A2 complex
Descriptor: ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, C25 alpha, ...
Authors:Mariuzza, R.A, Yang, X.
Deposit date:2015-08-05
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.
J.Biol.Chem., 290, 2015
5EOT
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BU of 5eot by Molmil
Structure of HLA-A2:01 with peptide G13E
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Zajonc, D.M, Remesh, S.G.
Deposit date:2015-11-10
Release date:2016-12-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
2X4U
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BU of 2x4u by Molmil
Crystal structure of MHC CLass I HLA-A2.1 bound to HIV-1 Peptide RT468-476
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ...
Authors:Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M.
Deposit date:2010-02-02
Release date:2010-03-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals.
J.Am.Chem.Soc., 131, 2009
5EUO
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BU of 5euo by Molmil
PF6-M1-HLA-A2
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Yang, X.
Deposit date:2015-11-18
Release date:2016-11-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of PF6-M1-HLA-A2 complex
To Be Published
3GSX
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BU of 3gsx by Molmil
Crystal structure of the binary complex between HLA-A2 and HCMV NLV-T8V peptide variant
Descriptor: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant T8V (NLVPMVAVV), ...
Authors:Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D.
Deposit date:2009-03-27
Release date:2009-08-04
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope.
J.Immunol., 183, 2009

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