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PDB: 37 results

1P7K
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Crystal structure of an anti-ssDNA antigen-binding fragment (Fab) bound to 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid (HEPES)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Schuermann, J.P, Henzl, M.T, Deutscher, S.L, Tanner, J.J.
Deposit date:2003-05-02
Release date:2004-05-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of an anti-DNA fab complexed with a non-DNA ligand provides insights into cross-reactivity and molecular mimicry.
Proteins, 57, 2004
1SEQ
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Fab MNAC13
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ISOPROPYL ALCOHOL, Monoclonal Antibody MNAC13, ...
Authors:Covaceuszach, S, Cattaneo, A, Lamba, D.
Deposit date:2004-02-18
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Neutralization of NGF-TrkA Receptor Interaction by the Novel Antagonistic anti-TrkA Monoclonal Antibody MNAC13: a Structural Insight
Proteins, 58, 2005
1T2Q
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The Crystal Structure of an NNA7 Fab that recognizes an N-type blood group antigen
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Fab NNA7 Heavy Chain, Fab NNA7 Light Chain, ...
Authors:Xie, K, Song, S.C, Spitalnik, S.L, Wedekind, J.E.
Deposit date:2004-04-22
Release date:2005-06-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal Structure and Mutational Analysis of an Antibody that Recognizes an N-type Blood Group Antigen
To be Published
1R3J
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potassium channel KcsA-Fab complex in high concentration of Tl+
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ...
Authors:Zhou, Y, MacKinnon, R.
Deposit date:2003-10-02
Release date:2003-11-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
1KEL
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CATALYTIC ANTIBODY 28B4 FAB FRAGMENT COMPLEXED WITH HAPTEN (1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO] METHYLPHOSPHONIC ACID)
Descriptor: 1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID, 28B4 FAB
Authors:Hsieh-Wilson, L.C, Schultz, P.G, Stevens, R.C.
Deposit date:1996-04-16
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution.
Proc.Natl.Acad.Sci.USA, 93, 1996
1GPO
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CRYSTAL STRUCTURE OF THE RATIONALLY DESIGNED ANTIBODY M41 AS A FAB FRAGMENT
Descriptor: ANTIBODY M41, SULFATE ION
Authors:Schiweck, W, Skerra, A.
Deposit date:1997-03-27
Release date:1998-04-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The rational construction of an antibody against cystatin: lessons from the crystal structure of an artificial Fab fragment.
J.Mol.Biol., 268, 1997
1BM3
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IMMUNOGLOBULIN OPG2 FAB-PEPTIDE COMPLEX
Descriptor: IMMUNOGLOBULIN OPG2 FAB, CONSTANT DOMAIN, VARIABLE DOMAIN
Authors:Kodandapani, R, Veerapandian, L, Ni, C.Z, Chiou, C.-K, Whital, R, Kunicki, T.J, Ely, K.R.
Deposit date:1999-04-15
Release date:1999-04-20
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational change in an anti-integrin antibody: structure of OPG2 Fab bound to a beta 3 peptide.
Biochem.Biophys.Res.Commun., 251, 1998
1FNS
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CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR (VWF) A1 DOMAIN I546V MUTANT IN COMPLEX WITH THE FUNCTION BLOCKING FAB NMC4
Descriptor: IMMUNOGLOBULIN NMC-4 IGG1, VON WILLEBRAND FACTOR
Authors:Varughese, K.I.
Deposit date:2000-08-23
Release date:2000-10-18
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:von Willebrand factor conformation and adhesive function is modulated by an internalized water molecule.
Nat.Struct.Biol., 7, 2000
1OPG
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OPG2 FAB FRAGMENT
Descriptor: OPG2 FAB (HEAVY CHAIN), OPG2 FAB (LIGHT CHAIN)
Authors:Kodandapani, R, Veerapandian, B, Ely, K.R.
Deposit date:1995-04-28
Release date:1995-07-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the OPG2 Fab. An antireceptor antibody that mimics an RGD cell adhesion site.
J.Biol.Chem., 270, 1995
1P2C
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crystal structure analysis of an anti-lysozyme antibody
Descriptor: Lysozyme C, heavy chain VH+CH1 anti-lysozyme antibody F10.6.6, light chain anti-lysozyme antibody F10.6.6
Authors:Cauerhff, A, Goldbaum, F.A, Braden, B.C.
Deposit date:2003-04-15
Release date:2004-02-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural mechanism for affinity maturation of an anti-lysozyme antibody.
Proc.Natl.Acad.Sci.USA, 101, 2004
1CLO
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ANTI-CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY A5B7
Descriptor: A5B7 MONOCLONAL ANTIBODY
Authors:Banfield, M.J, King, D.J, Mountain, A, Brady, R.L.
Deposit date:1996-05-01
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs.
Proteins, 29, 1997
1KEM
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CATALYTIC ANTIBODY 28B4 FAB FRAGMENT
Descriptor: 28B4 FAB
Authors:Hsieh-Wilson, L.C, Schultz, P.G, Stevens, R.C.
Deposit date:1996-04-16
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution.
Proc.Natl.Acad.Sci.USA, 93, 1996
1CT8
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CATALYTIC ANTIBODY 7C8 COMPLEX
Descriptor: 7C8 FAB FRAGMENT; LONG CHAIN, 7C8 FAB FRAGMENT; SHORT CHAIN, SULFATE ION, ...
Authors:Gigant, B, Tsumuraya, T, Fujii, I, Knossow, M.
Deposit date:1999-08-20
Release date:1999-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Diverse structural solutions to catalysis in a family of antibodies.
Structure Fold.Des., 7, 1999
1OAK
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CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR (VWF) A1 DOMAIN IN COMPLEX WITH THE FUNCTION BLOCKING NMC-4 FAB
Descriptor: NMC-4 IGG1, VON WILLEBRAND FACTOR
Authors:Celikel, R, Varughese, K.I.
Deposit date:1997-12-18
Release date:1998-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the von Willebrand factor A1 domain in complex with the function blocking NMC-4 Fab.
Nat.Struct.Biol., 5, 1998
1EMT
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FAB ANTIBODY FRAGMENT OF AN C60 ANTIFULLERENE ANTIBODY
Descriptor: IGG ANTIBODY (HEAVY CHAIN), IGG ANTIBODY (LIGHT CHAIN)
Authors:Braden, B.C, Goldbaum, F.A, Chen, B.-X, Erlanger, B.F, Kirschner, A.N, Wilson, S.R.
Deposit date:2000-03-17
Release date:2000-11-01
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:X-ray crystal structure of an anti-Buckminsterfullerene antibody fab fragment: biomolecular recognition of C(60).
Proc.Natl.Acad.Sci.USA, 97, 2000
1K4D
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Potassium Channel KcsA-Fab complex in low concentration of K+
Descriptor: DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ...
Authors:Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R.
Deposit date:2001-10-07
Release date:2001-11-14
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution.
Nature, 414, 2001
1R3I
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potassium channel KcsA-Fab complex in Rb+
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ...
Authors:Zhou, Y, MacKinnon, R.
Deposit date:2003-10-02
Release date:2003-11-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
1R3L
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potassium channel KcsA-Fab complex in Cs+
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, CESIUM ION, ...
Authors:Zhou, Y, MacKinnon, R.
Deposit date:2003-10-02
Release date:2003-11-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
1MLC
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MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME COMPLEXED WITH LYSOZYME
Descriptor: HEN EGG WHITE LYSOZYME, IGG1-KAPPA D44.1 FAB (HEAVY CHAIN), IGG1-KAPPA D44.1 FAB (LIGHT CHAIN)
Authors:Braden, B.C, Souchon, H, Eisele, J.-L, Bentley, G.A, Bhat, T.N, Navaza, J, Poljak, R.J.
Deposit date:1995-03-10
Release date:1995-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1.
J.Mol.Biol., 243, 1994
1RIH
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Crystal Structure of Fab 14F7, a unique anti-tumor antibody specific for N-glycolyl GM3
Descriptor: heavy chain of antibody 14F7, light chain of antibody 14F7
Authors:Krengel, U, Olsson, L.-L, Martinez, C, Talavera, A, Rojas, G, Mier, E, Angstrom, J, Moreno, E.
Deposit date:2003-11-17
Release date:2004-01-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and Molecular Interactions of a Unique Antitumor Antibody Specific for N-Glycolyl GM3.
J.Biol.Chem., 279, 2004
1FDL
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CRYSTALLOGRAPHIC REFINEMENT OF THE THREE-DIMENSIONAL STRUCTURE OF THE FAB D1.3-LYSOZYME COMPLEX AT 2.5-ANGSTROMS RESOLUTION
Descriptor: HEN EGG WHITE LYSOZYME, IGG1-KAPPA D1.3 FAB (HEAVY CHAIN), IGG1-KAPPA D1.3 FAB (LIGHT CHAIN)
Authors:Fischmann, T.O, Poljak, R.J.
Deposit date:1990-08-27
Release date:1991-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5-A resolution.
J.Biol.Chem., 266, 1991
1MF2
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ANTI HIV1 PROTEASE FAB COMPLEX
Descriptor: MONOCLONAL ANTIBODY F11.2.32
Authors:Lescar, J, Bentley, G.A.
Deposit date:1996-12-27
Release date:1997-12-31
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three-dimensional structure of an Fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody.
J.Mol.Biol., 267, 1997
1DBJ
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MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY
Descriptor: AETIOCHOLANOLONE, IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN)
Authors:Arevalo, J.H, Wilson, I.A.
Deposit date:1993-08-24
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of crossreactivity and the limits of antibody-antigen complementarity.
Nature, 365, 1993
1DBB
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THREE-DIMENSIONAL STRUCTURE OF AN ANTI-STEROID FAB' AND PROGESTERONE-FAB' COMPLEX
Descriptor: IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN), PROGESTERONE
Authors:Arevalo, J.H, Wilson, I.A.
Deposit date:1992-11-11
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex.
J.Mol.Biol., 231, 1993
1DBM
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MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY
Descriptor: IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN), PROGESTERONE-11-ALPHA-OL-HEMISUCCINATE
Authors:Arevalo, J.H, Wilson, I.A.
Deposit date:1993-08-24
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of crossreactivity and the limits of antibody-antigen complementarity.
Nature, 365, 1993

 

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