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PDB: 8 results
1WWW
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BU of 1www by Molmil
NGF IN COMPLEX WITH DOMAIN 5 OF THE TRKA RECEPTOR
Descriptor: PROTEIN (NERVE GROWTH FACTOR), PROTEIN (TRKA RECEPTOR)
Authors:Wiesmann, C, Ultsch, M.H, De Vos, A.M.
Deposit date:1999-03-12
Release date:1999-09-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor.
Nature, 401, 1999
1SG1
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BU of 1sg1 by Molmil
Crystal Structure of the Receptor-Ligand Complex between Nerve Growth Factor and the Common Neurotrophin Receptor p75
Descriptor: Beta-nerve growth factor, CHLORIDE ION, Tumor necrosis factor receptor superfamily member 16
Authors:He, X.L, Garcia, K.C.
Deposit date:2004-02-22
Release date:2004-06-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of nerve growth factor complexed with the shared neurotrophin receptor p75
Science, 304, 2004
4ZBN
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Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-nerve growth factor, DNA (28-MER)
Authors:Davies, D.R, Edwards, T.E.
Deposit date:2015-04-15
Release date:2015-06-10
Last modified:2015-07-15
Method:X-RAY DIFFRACTION (2.447 Å)
Cite:Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.
Structure, 23, 2015
4EDW
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Nerve Growth Factor in Complex with Fab from humanized version of mouse mAb 911 (tanezumab)
Descriptor: Beta-nerve growth factor, GLYCEROL, tanezumab Fab heavy chain, ...
Authors:Eigenbrot, C, Ultsch, M.
Deposit date:2012-03-27
Release date:2014-04-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
MAbs, 6
4EDX
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Nerve Growth Factor in Complex with Fab from mouse mAb 911
Descriptor: Beta-nerve growth factor, heavy chain of Fab of murine anti-NGF, light chain of FAB of murine anti-NGF
Authors:Eigenbrot, C, Ultsch, M.
Deposit date:2012-03-27
Release date:2014-04-02
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
MAbs, 6
5JZ7
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NGF IN COMPLEX WITH MEDI578 scFv
Descriptor: Beta-nerve growth factor, MEDI578 scFv, heavy chain, ...
Authors:Olsson, L.-L, Aagaard, A.
Deposit date:2016-05-16
Release date:2017-01-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.
Sci Rep, 6, 2016
2IFG
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Structure of the extracellular segment of human TRKA in complex with nerve growth factor
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-nerve growth factor, High affinity nerve growth factor receptor, ...
Authors:He, X, Garcia, K.C.
Deposit date:2006-09-20
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors.
Neuron, 53, 2007
6YW8
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NMR solution structure of unbound recombinant human Nerve Growth Factor (rhNGF)
Descriptor: Beta-nerve growth factor
Authors:Golic Grdadolnik, S, Paoletti, F.
Deposit date:2020-04-29
Release date:2021-05-12
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:Endogenous modulators of neurotrophin signaling: Landscape of the transient ATP-NGF interactions.
Comput Struct Biotechnol J, 19, 2021

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