6MBK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mbk by Molmil](/molmil-images/mine/6mbk) | SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, First P212121 Crystal Form | Descriptor: | 1,2-ETHANEDIOL, Actin peptide, GLYCEROL, ... | Authors: | Horton, J.R, Dai, S, Cheng, X. | Deposit date: | 2018-08-30 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | SETD3 is an actin histidine methyltransferase that prevents primary dystocia. Nature, 565, 2019
|
|
6OX0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ox0 by Molmil](/molmil-images/mine/6ox0) | SETD3 in Complex with an Actin Peptide with Sinefungin Replacing SAH as Cofactor | Descriptor: | 1,2-ETHANEDIOL, Actin Peptide, Histone-lysine N-methyltransferase setd3, ... | Authors: | Horton, J.R, Dai, S, Cheng, X. | Deposit date: | 2019-05-13 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.755 Å) | Cite: | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
|
|
6MBJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mbj by Molmil](/molmil-images/mine/6mbj) | SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, P21 Crystal Form | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ... | Authors: | Horton, J.R, Dai, S, Cheng, X. | Deposit date: | 2018-08-30 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | SETD3 is an actin histidine methyltransferase that prevents primary dystocia. Nature, 565, 2019
|
|
6OX3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ox3 by Molmil](/molmil-images/mine/6ox3) | SETD3 in Complex with an Actin Peptide with His73 Replaced with Lysine | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ... | Authors: | Horton, J.R, Dai, S, Cheng, X. | Deposit date: | 2019-05-13 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.785 Å) | Cite: | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
|
|
7W28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w28 by Molmil](/molmil-images/mine/7w28) | |
6OX1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ox1 by Molmil](/molmil-images/mine/6ox1) | SETD3 in Complex with an Actin Peptide with Target Histidine Partially Methylated | Descriptor: | 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ... | Authors: | Horton, J.R, Dai, S, Cheng, X. | Deposit date: | 2019-05-13 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.949 Å) | Cite: | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
|
|
6ICT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ict by Molmil](/molmil-images/mine/6ict) | Structure of SETD3 bound to SAH and methylated actin | Descriptor: | Actin, cytoplasmic 1, Histone-lysine N-methyltransferase setd3, ... | Authors: | Guo, Q, Liao, S, Xu, C, Structural Genomics Consortium (SGC) | Deposit date: | 2018-09-07 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.952 Å) | Cite: | Structural insights into SETD3-mediated histidine methylation on beta-actin. Elife, 8, 2019
|
|
6V63
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v63 by Molmil](/molmil-images/mine/6v63) | SETD3 WT in Complex with an Actin Peptide with His73 Replaced with Glutamine | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Actin, ... | Authors: | Dai, S, Horton, J.R, Cheng, X. | Deposit date: | 2019-12-04 | Release date: | 2020-01-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation. J.Biol.Chem., 295, 2020
|
|
6OX2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ox2 by Molmil](/molmil-images/mine/6ox2) | SETD3in Complex with an Actin Peptide with the Target Histidine Fully Methylated | Descriptor: | 1,2-ETHANEDIOL, Actin Peptide, GLYCEROL, ... | Authors: | Horton, J.R, Dai, S, Cheng, X. | Deposit date: | 2019-05-13 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.089 Å) | Cite: | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
|
|
6OX5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ox5 by Molmil](/molmil-images/mine/6ox5) | A SETD3 Mutant (N255A) in Complex with an Actin Peptide with His73 Replaced with Lysine | Descriptor: | 1,2-ETHANEDIOL, Actin Peptide, Actin-histidine N-methyltransferase, ... | Authors: | Horton, J.R, Dai, S, Cheng, X. | Deposit date: | 2019-05-13 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.098 Å) | Cite: | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
|
|
6ICV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6icv by Molmil](/molmil-images/mine/6icv) | Structure of SETD3 bound to SAH and unmodified actin | Descriptor: | Actin, cytoplasmic 1, Histone-lysine N-methyltransferase setd3, ... | Authors: | Guo, Q, Liao, S, Xu, C, Structural Genomics Consortium (SGC) | Deposit date: | 2018-09-07 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural insights into SETD3-mediated histidine methylation on beta-actin. Elife, 8, 2019
|
|
6MBL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mbl by Molmil](/molmil-images/mine/6mbl) | SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, Second P212121 Crystal Form | Descriptor: | 1,2-ETHANEDIOL, Actin Peptide, Histone-lysine N-methyltransferase setd3, ... | Authors: | Horton, J.R, Dai, S, Cheng, X. | Deposit date: | 2018-08-30 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.197 Å) | Cite: | SETD3 is an actin histidine methyltransferase that prevents primary dystocia. Nature, 565, 2019
|
|
3D2U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d2u by Molmil](/molmil-images/mine/3d2u) | Structure of UL18, a Peptide-Binding Viral MHC Mimic, Bound to a Host Inhibitory Receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Actin, Beta-2-microglobulin, ... | Authors: | Yang, Z, Bjorkman, P.J. | Deposit date: | 2008-05-08 | Release date: | 2008-07-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptor Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
8OI8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8oi8 by Molmil](/molmil-images/mine/8oi8) | Cryo-EM structure of ADP-bound, filamentous beta-actin harboring the R183W mutation | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Oosterheert, W, Blanc, F.E.C, Roy, A, Belyy, A, Hofnagel, O, Hummer, G, Bieling, P, Raunser, S. | Deposit date: | 2023-03-22 | Release date: | 2023-08-16 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (2.28 Å) | Cite: | Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments. Nat.Struct.Mol.Biol., 30, 2023
|
|
6OX4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ox4 by Molmil](/molmil-images/mine/6ox4) | A SETD3 Mutant (N255A) in Complex with an Actin Peptide | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ... | Authors: | Horton, J.R, Dai, S, Cheng, X. | Deposit date: | 2019-05-13 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.294 Å) | Cite: | Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
|
|
8OID
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8oid by Molmil](/molmil-images/mine/8oid) | Cryo-EM structure of ADP-bound, filamentous beta-actin harboring the N111S mutation | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Oosterheert, W, Blanc, F.E.C, Roy, A, Belyy, A, Hofnagel, O, Hummer, G, Bieling, P, Raunser, S. | Deposit date: | 2023-03-22 | Release date: | 2023-08-09 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments. Nat.Struct.Mol.Biol., 30, 2023
|
|
6V62
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v62 by Molmil](/molmil-images/mine/6v62) | SETD3 double mutant (N255F/W273A) in Complex with an Actin Peptide with His73 Replaced with Lysine | Descriptor: | 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ... | Authors: | Dai, S, Horton, J.R, Cheng, X. | Deposit date: | 2019-12-04 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation. J.Biol.Chem., 295, 2020
|
|
8QR1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qr1 by Molmil](/molmil-images/mine/8qr1) | Cryo-EM structure of the human Tip60 complex | Descriptor: | Actin, cytoplasmic 1, N-terminally processed, ... | Authors: | Li, C, Smirnova, E, Schnitzler, C, Crucifix, C, Concordet, J.P, Brion, A, Poterszman, A, Schultz, P, Papai, G, Ben-Shem, A. | Deposit date: | 2023-10-06 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structure of human TIP60-C histone exchange and acetyltransferase complex Nature, 2024
|
|
6NBW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nbw by Molmil](/molmil-images/mine/6nbw) | Ternary Complex of Beta/Gamma-Actin with Profilin and AnCoA-NAA80 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Rebowski, G, Boczkowska, M, Dominguez, R. | Deposit date: | 2018-12-10 | Release date: | 2020-01-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanism of actin N-terminal acetylation. Sci Adv, 6, 2020
|
|
9C57
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9c57 by Molmil](/molmil-images/mine/9c57) | Reconstituted P400 Subcomplex of the human TIP60 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E. | Deposit date: | 2024-06-05 | Release date: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex. Science, 2024
|
|
7W29
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w29 by Molmil](/molmil-images/mine/7w29) | |
8DNH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dnh by Molmil](/molmil-images/mine/8dnh) | Cryo-EM structure of nonmuscle beta-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | Deposit date: | 2022-07-11 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Structural insights into actin isoforms. Elife, 12, 2023
|
|
8X1C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8x1c by Molmil](/molmil-images/mine/8x1c) | Structure of nucleosome-bound SRCAP-C in the ADP-bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y. | Deposit date: | 2023-11-06 | Release date: | 2024-03-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insights into histone exchange by human SRCAP complex. Cell Discov, 10, 2024
|
|
8X15
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8x15 by Molmil](/molmil-images/mine/8x15) | Structure of nucleosome-bound SRCAP-C in the apo state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y. | Deposit date: | 2023-11-06 | Release date: | 2024-03-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insights into histone exchange by human SRCAP complex. Cell Discov, 10, 2024
|
|
8X19
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8x19 by Molmil](/molmil-images/mine/8x19) | Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y. | Deposit date: | 2023-11-06 | Release date: | 2024-03-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insights into histone exchange by human SRCAP complex. Cell Discov, 10, 2024
|
|