7W28

Crystal Structure of SETD3-SAH in complex with betaA-4PyrAla73 peptide

Summary for 7W28

• Entry DOI: 10.2210/pdb7w28/pdb
• Descriptor: Histone-lysine N-methyltransferase setd3, Actin, cytoplasmic 1, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
• Functional Keywords: set domain, structural protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 59712.65

Authors

Li, H.,Ma, H. (deposition date: 2021-11-22, release date: 2022-10-05, Last modification date: 2023-11-29)

• Primary citation: Hintzen, J.C.J.,Ma, H.,Deng, H.,Witecka, A.,Andersen, S.B.,Drozak, J.,Guo, H.,Qian, P.,Li, H.,Mecinovic, J.; Histidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin.; Protein Sci., 31:e4305-e4305, 2022; PubMed: 35481649; DOI: 10.1002/pro.4305

Experimental method

X-RAY DIFFRACTION (1.79 Å)