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7W28

Crystal Structure of SETD3-SAH in complex with betaA-4PyrAla73 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Histone-lysine N-methyltransferase setd3polymer49957223.01UniProt (Q86TU7)
Pfam (PF00856)
Pfam (PF09273)
Homo sapiens (Human)SET domain-containing protein 3
2B
(P)
Actin, cytoplasmic 1polymer161913.11UniProt (P60709)Homo sapiensBeta-actin
3C
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
4D, E
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
5F, G
(A, P)
waterwater18.0514Chemie (HOH)
Sequence modifications
A: 0 - 497 (UniProt: Q86TU7)
PDBExternal DatabaseDetails
Ser -1-expression tag
P: 66 - 81 (UniProt: P60709)
PDBExternal DatabaseDetails
N9p 73His 73conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59136.1
Non-Polymers*Number of molecules3
Total formula weight576.5
All*Total formula weight59712.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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